A5101509995- Signaling Pathways in Disease
- Cancer, Lipids, and Metabolism
- PI3K/AKT/mTOR signaling in cancer
- IoT and Edge/Fog Computing
- Epilepsy research and treatment
- Enzyme Production and Characterization
- Genetics and Neurodevelopmental Disorders
- Lipoproteins and Cardiovascular Health
- Privacy-Preserving Technologies in Data
- Protease and Inhibitor Mechanisms
- Industrial Vision Systems and Defect Detection
- Polyamine Metabolism and Applications
- Genetics, Aging, and Longevity in Model Organisms
- Cholesterol and Lipid Metabolism
- Glycosylation and Glycoproteins Research
- Protein Kinase Regulation and GTPase Signaling
- Biofuel production and bioconversion
- Lipid metabolism and biosynthesis
- Metabolism and Genetic Disorders
- Galectins and Cancer Biology
- Pancreatic function and diabetes
- Cloud Computing and Resource Management
- Polysaccharides and Plant Cell Walls
- Connective tissue disorders research
- Toxin Mechanisms and Immunotoxins
Tianjin University
2024
Tianjin Children's Hospital
2024
Tianma Microelectronics (China)
2023
Inner Mongolia University
2018-2021
Jiangsu University
2019
Shanxi Medical University
2015
Ollscoil na Gaillimhe – University of Galway
2011
University College Dublin
2011
DEPDC5 emerges to play a vital role in focal epilepsy. However, genotype-phenotype correlation DEPDC5-related epilepsies is challenging and controversial. In this study, we aim investigate the genotypic phenotypic features DEPDC5-affected patients.
In the enzymatic conversion of biomass, it becomes an important issue to efficiently and cost-effectively degrade cellulose into fermentable glucose. β-Glucosidase (Bgluc), essential member cellulases, plays a critical role in cellulosic biomass degradation. The difficulty improving stability Bgluc has been bottleneck enzyme-dependent traditional method protein purification, however, leads higher production cost decrease activity. To simplify purify with modified special properties,...
The mechanistic target of rapamycin complex 2 (mTORC2) primarily functions as an effector insulin/PI3K signaling to regulate cell proliferation and is associated with metabolism. However, the function mTORC2 in lipid metabolism not well understood. In present study, was inactivated by ATP-competitive mTOR inhibitor AZD8055 or shRNA targeting RICTOR primary bovine mammary epithelial cells (pBMECs). MTT assay performed examine effect on proliferation. ELISA GC-MS analysis were used determine...
This study investigated the effects of Na2SO3 on fat metabolism in human normal diploid HL-7702 (referred as L-02) hepatocytes. After 24 h and 48 h, treatment with different concentrations Na2SO3, intra extra-hepatocellular triglyceride (TG) contents L-02 were determined using chemical-enzymatic method. The very low-density lipoprotein (VLDL) apolipoprotein B100 (apoB100) culture supernatants enzyme-linked immunosorbent assay (ELISA). Western blot was applied to detect expressions fatty acid...
An extracellular signal-regulated kinase (ERK) is a mitogen-activated protein (MAPK) in mammalian cells that interact with the mechanistic target of rapamycin (mTOR) signalling pathway. ERK integrates signals from growth factors, nutrients, and mitogens to regulate cell proliferation, differentiation, cycle. The purpose this study was examine inhibitory effects U0126, specific MEK/ERK inhibitor, on mTOR signalling, Lipin 1 level, PPARγ activation, triglyceride (TAG) palmitic acid (PA)...
With an inbuilt structure of using the inorganic film passivation layer instead organic layers in Liquid Crystal Display with 7mask technology, sealing force is deteriorated. This paper devoted to find mechanism deterioration and developed a way improve.
SQSTM1 (sequestosome 1, also known as p62) is a multifunctional scaffold protein implicated in diverse cell physiology processes, such autophagy, signalling, and turnover. FKBP38 (FK506-binding 38) member of FKBPs family plays key role various cellular including signalling transduction, embryonic development apoptosis. In order to explore the SQSTM1/p62 gene cell-cycle progression proliferation goat foetal fibroblast (GFbs), was cloned characterized. Furthermore, yeast two-hybrid screening...