Abstract The carbon nanofibers and molybdenum disulfide (CNF-MoS 2 ) nanohybrid material was fabricated incorporated into epoxy resin to form the nanocomposite coating. Firstly, microstructure observation shows that each CNF uniformly wrapped up with MoS nanosheets, nanohybrids were well dispersed in Then, nanoindentation experiments carried out explore effect of CNF-MoS on mechanical properties results demonstrate elastic modulus, hardness creep deformation resistance coating are greatly...

We report an experimental investigation of the spontaneous motion liquid droplets on soft gels with a cross-linking gradient. By systematically adjusting spatial difference in density, we observed that millimeter-sized moved along elastic modulus gradient and even climbed inclined slopes against gravity. Unlike wetting dynamics micro-droplets, which are governed by elastocapillary effects, demonstrated movements were driven surface energy resulting from variations density. Using situ...

Abstract Background Circular RNAs (circRNAs) play an important role in osteoarthritis (OA). However, the of circRNA OA is still unclear. Here, we explored and mechanism circ_0044235 OA. Methods CHON-001 cells were treated with IL-1β to establish model vitro. The levels circ_0044235, miR-375 phosphoinositide 3-kinase (PI3K) regulatory subunit 3 (PIK3R3) detected by quantitative real-time PCR. Cell count kit-8 assay flow cytometry used detect cell viability apoptosis. concentrations...

Japanese encephalitis virus (JEV) is a highly fatal pathogen to human beings. Toll-like receptor 7 (TLR7) plays role as the first host defense against most single-stranded RNA flaviviruses. This study aims investigate of TLR7 in inducing adaptive immune response mice JEV. In vitro and vivo studies were conducted examine expression toll-like receptors (TLRs) mice. After JEV infection, physical parameters (survival rate body weight) evaluated, organs or cells collected for further analysis....

Liquid droplets on soft solids, such as polymeric gels, can induce substantial surface deformations, leading to the formation of wetting ridges at contact points. While these have been shown govern rich mechanics compliant substrates, inherently divergent characteristics points and multiphase nature reticulated gels pose great challenges for continuum mechanical theories in modeling phenomena. In this study, we report experimental characterizations emergence growth dynamics wetting-induced...

Osteoporosis is a severe bone disease characterized by decrease in the density and structure of bones, with high risks fractures. Pilose antler peptide (PAP), extracted purified from deer antlers, can promote regeneration fracture healing, strengthen sinews bone. To determine whether PAP osteoblast development to elucidate molecular mechanisms underlying its functions, present study investigated effects on proliferation, differentiation mineralization, role insulin signaling pathway using...

This paper presents a comprehensive study on determining the interface adhesive strength of polymer coating/substrate system to improve its durability. Interfacial stress intensity factors based crack tip opening displacement (CTOD) method were theoretically analysed and verified by finite element simulation. Thereafter, an experimental setup was established with micro-scale digital image correlation (DIC) measure CTODs designed loading fixture for multi-angle loading. The apparent specimen...

Due to its rich nutritional value, yak milk is an important food source in the alpine pastoral areas. However, yaks have a low yield. The Hippo pathway participates cell proliferation and organ development. We aimed determine regulatory mechanism of this mammary cells. A greater understanding how expression essential genes influence reproductive cycle could lead improvements lactation performance. levels key MST1, LATS1, YAP1, TEAD1 were detected by quantitative real-time PCR, Western...

This paper designs an embedded displacement measuring device based on error separating technique of multi-circle overlapping three-probe method. Considering the requirement high precision and speed modern CNC machine, accuracy CCD laser sensor is used in system to measure rotating spindle, then send result PC for further analysis by software. According experiment, roundness errors separated such method are totally similar, rotation increase as accelerated a certain speed. All these realistic.

To reduce the influence of geometric error on machining precision CNC machine, a new method based multi-body system theory and laser sequential step diagonal vector measurement to distinguish errors machine tool was presented. Firstly modeling established. Then introduced. Finally comparison experiments directly traditional were done, besides, compensation experiment done. The results show that combined is feasible after accuracy improved by 63%.

Composite multipoint thermometric system of CNC machine tools includes 64 digital temperature sensors 16 thermocouples and 8 thermal resistances. Its accuracy can reach ± 0.5°C its special function contains saving data drawing picture after measuring. The works stably reliably during the test measuring satisfy requirements mathematical modeling.

Digital image correlation (DIC) combined with an optical microscope has been used to realize the micro scale deformation measurement; micro-scale speckle pattern film was fabricated by spinning epoxy resin and powder, transferred surface of a test specimen. Generally, measurement accuracy 2D DIC will be affected small out-of-plane displacement However, telecentric lens is not convenient in digital minimize error. Thus, error due geometrical aberration, or distortion, should corrected...

Objective: To investigate the clinical efficacy of PHILOS plates in treatment Vancouver B1 periprosthetic femoral fracture (PFF) and to validate its biomechanical reliability via finite element analysis mechanical testing on Synbone models. Methods: Ten males eight females with PFF who underwent plate fixation between September 2017 January 2022 were selected. The average age was 72.61 ± 8.19 years, a range 57-86 years old. X-ray films taken assess healing situation around prosthesis as well...

Liquid droplets on soft solids, such as polymeric gels, can induce substantial surface deformations, leading to the formation of wetting ridges at contact points. While these have been shown govern rich mechanics compliant substrates, inherently divergent characteristics points and multiphase nature reticulated gels pose great challenges for continuum mechanical theories in modeling phenomena. In this study, we report in-situ experimental characterizations emergence growth dynamics...

Ionic polymer–metal composite (IPMC) cantilever actuator demonstrates significant bending deformation upon application of excitation voltage across electrodes without external load. In the present work, non-contact digital image correlation (DIC) and a microscope were used to investigate micro-scale displacement strain distributions on cross section under voltages, according low mass film properties IPMC material. The target surface fabricated sample with Pt was roughened fine sandpapers...

In the process of metal welding, residual stress will inevitably be introduced. real service environment, also undergo further evolution and development, which directly affect properties materials or components, then threaten safety life property. Therefore, it is great practical value to study rapid accurate measurement method stress. Traditional test methods have their limitations, thus, someone proposed that magnitude direction can characterized based on morphology after unloading...