Acinetobacter baumannii has emerged as a main nosocomial pathogen exhibiting high rates of resistance to clinically relevant antibiotics. Six pandrug-resistant A. (PDR-A. baumannii) were recovered from three patients in Tunisian Intensive Care Unit (ICU) between 10th and 16th May 2018 resulting one fatal case raising the possibility an outbreak. On 18th environmental screening ICU surfaces was carried out. 22nd fourth patient infected with PDR-A. died. A second investigation out for isolated...

Antimicrobial-resistant Escherichia coli isolates have emerged in various ecologic compartments and evolved to spread globally. We sought (1.) investigate the occurrence of ESBL-producing E. (ESBL-Ec) feces from free-range chickens a rural region (2.) characterize genetic background antimicrobial resistance relatedness collected isolates. Ninety-five swabs associated with two households (House 1/House 2) northern Tunisia were collected. Samples screened recover ESBL-Ec, characterized for...

Abstract Aims Carbapenem-resistant Acinetobacter baumannii (CR-Ab) is an important cause of infections in burn patients. This study aimed to characterize the antimicrobial susceptibility pattern CR-Ab isolated from burns Burn Intensive Care Unit (BICU) Trauma and Centre Ben Arous, determine prevalence β-lactamase-encoding genes search eventual genetic relatedness strains. Methods Results From 15 December 2016 2 April 2017, all nonduplicated patients BICU were screened by simplex Polymerase...

Background Pneumococcal disease, a major cause of morbidity and mortality globally, has higher incidence among young children, the elderly immunocompromised all ages. In Tunisia, pneumococcal conjugate vaccines (PCVs) are not included in national immunization program. Also, few studies have described epidemiology S. pneumoniae this country and, particular, no molecular typing been performed. The aim study was to evaluate serotype distribution, antimicrobial resistance clonality Streptococcus...

Worldwide, studies regarding antimicrobial resistance in rabbits are scarce. In addition, it seems that rearing conditions have important impact on emergence and spread of antimicrobial-resistant bacteria. Thus, the authors sought to (1) assess role residing across diverse ecosystems as potential reservoirs enterococci (2) investigate genetic background detected resistances.Faecal samples from 60 healthy farmed (one farm), 35 laboratory 31 wild were analysed. Overall, 97 isolates...

Abstract Pseudomonas aeruginosa is one of the major infectious agents in burn patients. Globally, high rates antimicrobial resistance P. have been reported, which a cause concern. The objective this study was to determine rate carbapenems isolates recovered from patients Tunisia, search genes encoding for carbapenemases and their epidemiological markers (serotypes). A retrospective conducted Burn Intensive Care Unit (BICU) Trauma Centre Ben Arous, collected patients, January December 2018...

ABSTRACT Little is known about the role of forestland and non-fertilized agriculture soils as reservoirs extended-spectrum beta-lactamase (ESBL) plasmid-borne AmpC (pAmpC)-producing Escherichia coli isolates. Thus, in present study, 210 soil samples from various origins (forest Oued Zen (Ain Drahem), non-agriculture different park gardens Tunis City, cereal culture home gardens) were investigated to characterize cefotaxime-resistant E. A total 22 ESBL/pAmpC-producing collected, all harbored...

Abstract Extensively drug resistant Acinetobacter baumannii (XDR- Ab ), has emerged as an important pathogen in several outbreaks. The aim of our study was to investigate the eventual genetic relatedness XDR- strains recovered from burn patients and environment sites largest Tunisian Burn Intensive Care Unit (BICU) characterize β-lactamase encoding genes these strains. Between March 04th, 2019 April 22nd, outbreak suspected. Environmental screening done. All isolates were screened by simplex...

We aimed to study the antibiotic susceptibility and possible occurrence of extended-spectrum beta-lactamases (ESBL)/carbapenemase-producing Escherichia coli isolates collected from rabbits in Tunisia. In all, 35 faecal samples healthy were one farm E. isolated three media: antibiotic-free TBX agar, TBX+2 mg l−1 cefotaxime TBX+1 imipenem. total, 39 recovered; majority showed resistance at least none was ESBL producer. Carbapenem detected 16 either selective or un-selective media. Phenotypic...

Carbapenem resistant Enterobacteriaceae (CRE) are major human pathogens because, these cause high number of difficult-to-treat infections. Allogeneic hematopoietic stem cell transplant (AHSCT) recipients highly exposed to type bacteria. The aim our study was investigate prevalence CRE colonization in AHSCT patients and determine genes encoding carbapenem resistance. A retrospective conducted between January 2015 December 2019, involved 55 colonized with strains. We determined the rate...

<abstract> <p>Low-dose ionizing radiation can trigger a phenomenon known as hormesis in microorganisms, which exposure to mild stressors like results beneficial adaptive responses. This study investigated the impact of low-dose X-rays on <italic>Escherichia coli</italic>'s viability and their potential influence antibiotic susceptibility. The irradiated samples displayed increased bacterial compared non-irradiated controls, with significant increase observed at 5 10...

In Tunisia, limited research has focused on characterizing clinical vancomycin-resistant Enterococcus faecium (VREfm). This study aimed to bridge this knowledge gap by molecular characterization of antimicrobial resistance, determining the genetic elements mediating vancomycin-resistance, and whole-genome sequencing one representative VREfm isolate. Over 6 years (2011-2016), a total eighty isolates responsible for infection or colonization were identified from hospitalized patients, with...

This study aimed to screen and characterize colistin-resistant strains isolated from different livestock species in Algeria, including sheep, goats, dromedaries.

Vancomycin-resistant enterococci (VRE) are a public health concern as they lead to therapeutic impasses and play pivotal role in the dissemination of vancomycin resistance genes. As recent evidence suggests that wildlife can bacterial resistomes, this study explored potential Algerian wild birds reservoir VRE. A total 222 cloacal fecal samples were collected from various bird species screened for VRE using selective medium. Of 47 isolated strains, 22 identified Enterococcus casseliflavus...

This study aimed to characterize the first vancomycin-resistant