- Infrared Thermography in Medicine
- Thermoregulation and physiological responses
- Thermography and Photoacoustic Techniques
- Thermal Regulation in Medicine
- Diabetic Foot Ulcer Assessment and Management
- Spondyloarthritis Studies and Treatments
- Rheumatoid Arthritis Research and Therapies
- Bone and Joint Diseases
- History and Developments in Astronomy
- Calibration and Measurement Techniques
- Bone health and osteoporosis research
- Infrared Target Detection Methodologies
- Exercise and Physiological Responses
- thermodynamics and calorimetric analyses
- Birth, Development, and Health
- History of Science and Medicine
- Advanced Malware Detection Techniques
- Silymarin and Mushroom Poisoning
- Advanced Image Fusion Techniques
- Otitis Media and Relapsing Polychondritis
- Musculoskeletal synovial abnormalities and treatments
- Osteomyelitis and Bone Disorders Research
- Wound Healing and Treatments
- Optical Imaging and Spectroscopy Techniques
- Gas Dynamics and Kinetic Theory
Ionis Pharmaceuticals (United States)
2020-2023
University of South Wales
2005-2019
Royal National Hospital for Rheumatic Diseases
1974-2002
Bath Institute for Rheumatic Diseases
2002
Center for Rheumatology
1994
Southampton General Hospital
1994
Universitätszahnklinik Wien
1979
Medical University of Vienna
1978
University of Bath
1976
Peak bone mass is an important determinant of the risk osteoporotic fracture, and preventive strategies against osteoporosis require a clear understanding factors influencing gain in early life. We report longitudinal study aiming to identify relationships between childhood growth, lifestyle, peak women. One hundred fifty-three women born British city during 1968-1969 were traced studied 1990. Data on their growth was obtained from linked birth school health records; current mineral...
Early identification of areas inflammation may aid prevention diabetic foot ulcers. A new bespoke thermal camera system has been developed to thermally image feet at risk. Hotspots (areas least 2.2 °C hotter than the contralateral site) indicate prior any apparent visual signs. This article describes pattern and symmetry 103 healthy pairs feet. 68% participants were symmetric 33 sites measured. 32% had one hotspot, but hotspots overall only accounted for 5% measurements made. Refinements...
Abstract Background Thermal imaging is a useful modality for identifying preulcerative lesions (“hot spots”) in diabetic foot patients. Despite its recognised potential, at present, there no readily available instrument routine podiatric assessment of patients risk. To address this need, novel thermal system was recently developed. This paper reports the reliability device temperature healthy feet. Methods Plantar skin temperatures were measured with (Diabetic Foot Ulcer Prevention System...
The measurement of temperature particularly with reference to medicine, had a slow beginning the primitive thermometers sixteenth century. Dr Carl Wunderlich, great pioneer in clinical thermometry showed real significance use measurements for both diagnoses fever and also monitoring course relation medical condition his patients. radiometric determination human body is however more modern. Remote sensing infrared radiation became practical value 1940s has continued develop steadily since...
Abstract Aim To assess the usefulness of monthly thermography and standard foot care to reduce diabetic ulcer recurrence. Methods People with diabetes ( n = 110), neuropathy history ≥ 1 participated in a single‐blind multicentre clinical trial. Feet were imaged novel thermal imaging device (Diabetic Foot Ulcer Prevention System). Participants randomized intervention (active + care) or control (blinded followed up until recurrence for 12 months. thermograms participants from group assessed...
There are several sites in which the human body core temperature can be estimated and used to identify febrile states a threat of pandemic situations at high-populational-traffic places (e.g. airports, ports, universities, schools, public buildings). In these locations, fast method is required for screening masses. The most common methods axillar tympanic thermometers. However, addition, measurement inner canthi (IC) eye with infrared thermal (IRT) imaging has been suggested as mass tool....
In this paper a description is given of the development, characterisation and first results thermal imaging device aimed at significantly reducing incidence diabetic foot ulceration (DFU). These devices will be used in three clinical centres two preliminary trials. The on healthy volunteers to set robust baseline for overall research aims second >100 patients high risk DFU. phase project objective demonstrate significant reduction DFU through comparison standard care feet with plus imaging.
A risk-based approach for routine identity testing of therapeutic oligonucleotide drug substances and products is described. Risk analysis solid-phase synthesis indicates that intact mass measurement a powerful technique confirming the intended oligonucleotide. Further risk assessment suggests addition second, sequence-sensitive test, which relies on comparison some property sample to reference standard proven identity, results in sufficient test most products. Alternative strategies product...
The discovery of infrared radiation by William Herschel in 1800 led to John Herschel’s study solar that he imaged evaporography. This termed a thermogram. measurement temperature medicine advanced with Dr Carl Wunderlich, who showed the significance use measurements for diagnosis fever and monitoring course relation disease. It was has ultimately opened up many applications thermal imaging. Radiometric determination human body (skin) is now achievable. Remote sensing first developed 1940s...
Objective: People with diabetic neuropathy who have previously ulcerated are at high risk of re-ulceration. They should regularly attend podiatry clinics for surveillance and routine protective podiatric treatment. It has been suggested that inflammation prior to skin breakdown shows up as a hotspot on thermal image even in the absence clinical signs. The aim this study is quantify inter-patient intra-patient variations presented by feet ulceration. Approach: Whole foot spot temperatures...
In digital imaging, poor contrast between the target and its background can affect extraction of object interest increase time used in analysis. Medical thermal imaging requires correct interpretation values obtained from region interest. this investigation, a subjective objective comparison currently available outlining techniques is performed to determine optimal method. Results indicate that probability-based operators produce best outcome especially after pre-processing with noise...
In recent years there has been a resurgence of interest in the application infrared thermal imaging medicine. Yet fairly little effort spent towards standardisation field and common communication exchange format for images. Most other medical areas where digital is employed have subscribed to DICOM (Digital Imaging Communication Medicine) as standard storing retrieving imagery. this paper we investigate how its current form can be adopted store communicate images
OBJECTIVES--To determine whether significant reduction in bone mass is detectable early disease patients with rheumatoid arthritis (RA) and to examine the possible influences of activity physical disability on mineral density (BMD) lumbar spine (LS) femoral neck (FN). METHODS--LS FN BMD values were measured Z scores determined a cross-sectional study 104 RA less than five years duration. also compared between subgroup 64 normal control group matched for age, sex, menopausal status body mass....