A5103270342- Molecular Sensors and Ion Detection
- Synthesis and Biological Evaluation
- Luminescence and Fluorescent Materials
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Artificial Intelligence in Law
- Nuclear Receptors and Signaling
- Intelligent Tutoring Systems and Adaptive Learning
- Online Learning and Analytics
- Catalytic C–H Functionalization Methods
- Sulfur Compounds in Biology
- Innovative Teaching and Learning Methods
- Apelin-related biomedical research
- Oxidative Organic Chemistry Reactions
- Genetics, Aging, and Longevity in Model Organisms
- Analytical Chemistry and Sensors
Wenzhou University
2025
Southeast University
2019-2021
China Pharmaceutical University
2020
Southeast University
2020
Chengdu Medical College
2019
Large language models (LLMs) have demonstrated remarkable proficiency in mainstream academic disciplines such as mathematics, physics, and computer science. However, human knowledge encompasses over 200 specialized disciplines, far exceeding the scope of existing benchmarks. The capabilities LLMs many these fields-particularly light industry, agriculture, service-oriented disciplines-remain inadequately evaluated. To address this gap, we present SuperGPQA, a comprehensive benchmark that...
A method for the synthesis of novel fused four-ring quinoxaline skeleton has been described by an I2 promoted sp3 C-H functionalization between 1,2,3,3-tetramethyl-3H-indolium iodides and 1,2-diamines. This transformation proceeds smoothly under metal- peroxide-free conditions through a sequential iodination, oxidation, annulation rearrangement. Moreover, 8,9-dichloro-5,12,12-trimethyl-2-(trifluoromethyl)-5,12-dihydroquinolino[2,3-b]quinoxaline showed good photophysical properties was used...
An “off–on” fluorescent probe was designed to detect palladium of all the typical oxidation states (0, +2, +4) without additional additives.
The G protein-coupled receptor APJ/Aplnr has been widely reported to be involved in heart and vascular development disease, but whether it contributes organ left-right patterning is largely unknown.Here, we show that zebrafish, aplnra/b coordinates LR an apela/apln ligand-dependent manner using distinct mechanisms at different stages.During gastrulation early somitogenesis, loss of function results liver asymmetry defects, accompanied by disturbed KV/cilia morphogenesis disrupted left-sided...
过氧化氢(H2O2)以分子信号的形式在各种生理和病理过程中都起着重要作用,因此快速、高效、灵敏地检测活细胞或生物体中的H2O2具有重要意义.本研究设计了一种新型的H2O2比率型荧光探针HDP-1,其对H2O2表现出比率荧光响应.探针HDP-1在H2O2检测方面具有选择性好、灵敏度高、细胞毒性低和反应速率快等优点,同时,该探针在检测活细胞中外源性和内源性H2O2都表现出了优异的性能.