A5054431826- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Skin Protection and Aging
- Pancreatic and Hepatic Oncology Research
- Global Cancer Incidence and Screening
- AI in cancer detection
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Surgical Treatments
- Cancer and Skin Lesions
- Hedgehog Signaling Pathway Studies
- Melanoma and MAPK Pathways
- Breast Cancer Treatment Studies
- Pancreatitis Pathology and Treatment
- Vitamin D Research Studies
- Infectious Diseases and Mycology
- Nail Diseases and Treatments
- Gastric Cancer Management and Outcomes
- Metabolism, Diabetes, and Cancer
- Plant Pathogens and Fungal Diseases
- Cutaneous lymphoproliferative disorders research
- Allergic Rhinitis and Sensitization
- Medieval Literature and History
- Dietary Effects on Health
- Historical, Religious, and Philosophical Studies
- Bone health and osteoporosis research
QIMR Berghofer Medical Research Institute
2015-2024
Hudson Institute
2019
Academy of Nutrition and Dietetics
2016
The University of Queensland
2011-2013
Queensland Health
2009-2012
Improvement Service
2011-2012
Cancer Council Queensland
2007-2009
Princess Alexandra Hospital
2006
Abstract Objective To investigate whether supplementing older adults with monthly doses of vitamin D alters the incidence major cardiovascular events. Design Randomised, double blind, placebo controlled trial (the D-Health Trial). Computer generated permuted block randomisation was used to allocate treatments. Setting Australia from 2014 2020. Participants 21 315 participants aged 60-84 years at enrolment. Exclusion criteria were self-reported hypercalcaemia, hyperparathyroidism, kidney...
Keratinocyte cancers (KCs), including basal cell carcinoma (BCC) and squamous (SCC), are the most common among fair-skinned populations worldwide. Although studies have indicated that anatomical distribution of BCC SCC differ, few compared them directly in well-defined population samples.To describe compare a population-based sample Queensland, Australia.This study was nested within QSkin Sun Health Study Australia. Of 37 103 participants linked to national medical insurance records, 3398...
Cutaneous melanomas are common cancers in white-skinned populations, and early detection is promoted as a means of reducing morbidity mortality. There concern that increased skin screening leading to overdiagnosis indolent with low risk lethality. The extent melanoma associated unknown.To estimate possible by comparing subsequent incidence biopsy rates among people subjected those who were not.We recruited 43 762 residents Queensland, Australia, aged 40-69 years, no prior history melanoma,...
The goal of surgeons treating soft tissue sarcoma is to gain local control, avoid risk recurrence and compromise the patient's potential survival. aim investigation was assess significance extent surgical margin on chance death, metastasis recurrence.Two hundred seventy-nine patients who presented with without metastatic disease were analysed.The not clinically or statistically significant in development disease. presence a contaminated led significantly higher rate (as did narrow less than...
Sunlight is the principal environmental risk factor for keratinocyte cancers, but other carcinogens have also been implicated, including tobacco smoke. Findings conflicting, however. We investigated associations between cigarette smoking and incidence of basal cell carcinoma (BCC) or squamous (SCC) in QSkin, a prospective study skin cancer (N = 43,794). Smoking history was self-reported at baseline; newly diagnosed BCCs SCCs were ascertained through data linkage verified by histopathology...
Risk stratification can improve the efficacy and cost-efficiency of screening programs for early detection cancer. We sought to derive a risk tool melanoma that was suitable general population using only self-reported information. used factor information collected at baseline from QSKIN, prospective cohort study Queensland adults age 40 69 years recruitment (n = 41 954). examined two separate outcomes: 1) invasive melanomas 2) all (invasive + in situ) obtained through data linkage cancer...
Sun exposure carries both harms and benefits. Exposing the skin to sun is main modifiable cause of cancers, which exert a considerable health economic burden in Australia. The most well-established benefit ultraviolet (UV) radiation vitamin D production. Australia has highest incidence cancer world but, despite high ambient UV radiation, approximately one quarter population estimated be deficient. Balancing risks benefits challenging requires effective communication. We sought provide...
Objective: To examine the trends in uptake of laparoscopic resection for colorectal cancer. Design and setting: Retrospective analysis Australia-wide data on elective resections cancer over 8 financial years 2000–01 to 2007–08, obtained from National Hospital Morbidity Database. Main outcome measures: annual percentage that were conducted laparoscopically each year, stratified by hospitals conducting a high volume (40 or more/year) versus low volume, public private hospitals. Results: For...
IMPORTANCE Primary prevention and early detection are integral strategies to reduce the burden of skin cancer.OBJECTIVES To describe prevalence sun protection examination practices in a population exposed high levels ambient solar radiation identify associated factors.DESIGN, SETTING, AND PARTICIPANTS Cross-sectional analyses baseline data from prospective cohort 40 172 adults aged through 69 years Queensland, Australia, recruited 2011.We obtained on all melanoma diagnoses 2009 via record...
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been postulated as chemopreventive agents for basal cell carcinoma (BCC) and squamous (SCC), but findings from observational studies inconsistent, clinical trial data are scant.To examine the association between aspirin NSAID (nonaspirin) use risk of BCC SCC in a large cohort specifically designed skin cancer outcomes.We used QSkin Study, prospective 43 764 residents Queensland, Australia (34 630 were included this study 23 581 our primary...
Background: Previous studies suggest that smokers have lower risks of cutaneous melanoma than nonsmokers, but data from population-based prospective are scarce. We investigated associations between smoking and in a cohort study purpose-designed to investigate skin cancer outcomes.Methods: Participants with no prior history (n = 38,697) completed risk factor survey at baseline (2011). Patients were followed through linkage the registry. estimated hazard ratios (HRs) 95% confidence intervals...
Background Melanoma develops as the result of complex interactions between sun exposure and genetic factors. However, data on these from prospective studies are scant. Objectives To quantify association ambient personal ultraviolet incident melanoma in a large population-based study men women residing setting high radiation, to examine potential gene–environment interactions. Methods Data were obtained QSkin Sun Health Study, cohort aged 40–69 years, randomly sampled Queensland population...
To describe the clinical settings in which keratinocyte cancers are excised Queensland and types of practitioners who excise them; to examine costs; identify predictors hospital admission.We used linked data for participants from QSkin study (n = 43 794), including Medicare claims admissions relating treatment episodes incident July 2011 June 2015. We multinomial logistic regression measure associations between demographic characteristics setting. The median costs (AU$) were...
Keratoacanthoma (KA) is a common and generally benign keratinocyte skin tumor. Reports of the incidence rates KA are scant. In addition, risk factors for not well understood, although associations with UV radiation exposure older age have been described.To investigate rate developing KA.The study included data from 40 438 193 344 randomly selected residents Queensland, Australia, who participated in QSkin Sun Health (QSkin) prospective population-based cohort study. All participants...
Not all cancer patients receive state-of-the-art care and providing regular feedback to clinicians might reduce this problem. The purpose of study was assess the utility various data sources in on quality care. Published clinical practice guidelines were used obtain a list processes-of-care interest clinicians. These assigned one four categories according their availability marginal cost using them for feedback. Only 8 (3%) 243 could be measured population-based registry or administrative...