Lin Zhu

ORCID: 0000-0003-0322-9321
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Endometriosis Research and Treatment
  • Reproductive System and Pregnancy
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Medical Imaging Techniques and Applications
  • Ovarian function and disorders
  • Lung Cancer Treatments and Mutations
  • Atomic and Subatomic Physics Research
  • Neonatal Respiratory Health Research
  • Effects of Radiation Exposure
  • Family and Disability Support Research
  • HIV-related health complications and treatments
  • Ultrasound and Hyperthermia Applications
  • Occupational and environmental lung diseases
  • bioluminescence and chemiluminescence research
  • Esophageal Cancer Research and Treatment
  • Trace Elements in Health
  • Colorectal Cancer Treatments and Studies
  • Photodynamic Therapy Research Studies
  • Advanced X-ray and CT Imaging
  • Cardiac Imaging and Diagnostics
  • Ectopic Pregnancy Diagnosis and Management
  • Congenital Anomalies and Fetal Surgery
  • Porphyrin and Phthalocyanine Chemistry
  • Radiomics and Machine Learning in Medical Imaging

Shanghai Chest Hospital
2022-2025

Shanghai Jiao Tong University
2022-2025

Heidelberg University
2022-2025

University Hospital Heidelberg
2022-2025

German Center for Lung Research
2022-2025

China International Science and Technology Cooperation
2023

Chongqing Medical University
2023

Children's Hospital of Chongqing Medical University
2023

Shanghai Medical College of Fudan University
2023

Shanghai University of Traditional Chinese Medicine
2022

Does uterine peristalsis influence the chance of clinical pregnancy in an embryo transfer cycle? The peristaltic wave frequency before is inversely related to rates fresh and frozen-thawed cycles. Uterine participates regulating fluid migration after mock transfer, but whether it could potentially outcomes had remained unclear. This prospective cohort study included a total 292 infertile women was conducted between March 2013 August 2013. Patients underwent stimulation cycle with long...

10.1093/humrep/deu058 article EN Human Reproduction 2014-03-23

Is there a difference in the characteristics of uterine peristalsis natural and controlled ovarian hyperstimulation (COH) cycles?COH significantly changed peristaltic pattern.In menstrual cycles, periodic changes are closely related to reproductive process.This is prospective cohort study with total 64 subjects involved. The was performed between May 2011 August 2011.Sixty-four infertile women regular, ovulatory cycles underwent follicular tracking one cycle after stimulation (GnRH-agonist...

10.1093/humrep/des257 article EN Human Reproduction 2012-07-14

What is the effect of uterine peristalsis on fluid migration after mock embryo transfer?Uterine peristaltic wave frequency was positively correlated with distance that moved it deposited in cavity.Embryos have been found outside cavity transfer. It has suggested contractions expelled these embryos.A prospective cohort study a total 112 infertile women conducted between March 2013 and May 2013.Uterine activity assessed before transfer, which 20 µl ultrasound contrast agent placed lumen 3 days...

10.1093/humrep/det429 article EN Human Reproduction 2013-11-25

This multicenter trial was conducted to evaluate MRI for the longitudinal management of incidental pulmonary nodules in heavy smokers. 239 participants (63.9 ± 8.4 years, 43-82 years) at risk or with COPD GOLDI-IV from 16 centers prospectively underwent two rounds same-day low-dose computed tomography (LDCT1&2) and MRI1&2 an interval three years nationwide COSYCONET trial. All exams were independently assessed a standardized fashion by blinded readers, incl. axis measurements Lung-RADS...

10.1007/s00330-025-11567-4 article EN cc-by European Radiology 2025-04-13

Bone marrow mesenchymal stem cell (BM-MSC) transplantation has been suggested to be a promising method for the treatment of pulmonary arterial hypertension (PAH), fatal disease currently without effective preventive/therapeutic strategies. However, detailed mechanisms underlying BM-MSC therapy are largely unknown. We designed present study test hypothesis that circulating platelets facilitate homing lung vasculature in rat model PAH induced by monocrotalin (MCT). A single subcutaneous...

10.3727/096368912x640529 article EN Cell Transplantation 2012-04-24

To investigate morphofunctional chest MRI for the detection and management of incidental pulmonary nodules in participants with chronic obstructive disease (COPD).In this prospective study, 567 (mean age, 66 years ± 9 [SD]; 340 men) underwent same-day contrast-enhanced nonenhanced low-dose CT (LDCT) a nationwide multicenter trial (clinicaltrials.gov: NCT01245933). Nodule dimensions, morphologic features, Lung Imaging Reporting Data System (Lung-RADS) category were assessed at by two blinded...

10.1148/ryct.220176 article EN Radiology Cardiothoracic Imaging 2023-04-01

Abstract Background Interstitial lung diseases (ILDs) can be induced and even exacerbated by radiotherapy in thoracic cancer patients. The roles of immune responses underlying the development these severe injuries are still obscure need to investigated. Methods A damage murine model was established delivering 16 Gy X-rays chest mice that had been pre-treated with bleomycin (BLM) thus hold ILDs. Bioinformatic analyses were performed on GEO datasets radiation-induced injury (RILI) BLM-induced...

10.1186/s12967-023-04177-5 article EN cc-by Journal of Translational Medicine 2023-05-09

Early detection of lung cancer in computed tomography (CT) can significantly improve the survival rate patients. A part early appeared form ground glass nodule (GGN), and its requires help a computer-aided algorithm. This study aimed to explore CT features GGN based on fuzzy C-means (FCM) clustering algorithm predicting invasion pulmonary adenocarcinoma. In this study, parenchyma from 65 patients with was segmented improved FCM cluster The region segmentation removed useless area, critical...

10.1016/j.jrras.2022.01.015 article EN cc-by-nc-nd Journal of Radiation Research and Applied Sciences 2022-03-01

The aim of this study was to develop a nomogram by combining chest computed tomography (CT) images and clinicopathological predictors assess the survival outcomes patients with primary pulmonary lymphoepithelial carcinoma (PLEC).

10.1186/s12931-024-02767-5 article EN cc-by Respiratory Research 2024-03-29

Muco-obstructive lung diseases are characterized by airway obstruction and hyperinflation, which can be quantified imaging. Our aim was to evaluate µCT for longitudinal quantification of muco-obstructive disease in β-epithelial Na+ channel overexpressing (Scnn1b-TG) mice the effects neutrophil elastase (NE) knockout on its progression. Lungs from wild-type (WT), NE-/-, Scnn1b-TG, Scnn1b-TG/NE-/- were scanned with 9-µm resolution at 0, 5, 14, 60 days age, parenchymal quantified. Mucus...

10.1152/ajplung.00341.2021 article EN AJP Lung Cellular and Molecular Physiology 2022-01-26

Chiari 0 malformation (CM-0) with syringomyelia syringobulbia and syrinx cavity in pons simultaneously is rare. We present a case of 31-year-old man, review the available literature, discuss experience therapy from neurosurgical perspective.

10.1016/j.inat.2016.06.005 article EN cc-by-nc-nd Interdisciplinary Neurosurgery 2016-06-17

This study aims to analyze the research hotspots, evolution, and developing trends in pediatric bronchiectasis over past 20 years using bibliometric analysis visualization tools identify potential new directions. Publications related children were retrieved from Web of Science Core Collection (WoSCC) database 2003 2022. Knowledge maps performed through VOSviewer1.6.18 CiteSpace6.1 R2. A total 2,133 publications searched, while only 1,351 original articles written English between 2022...

10.3389/fped.2023.1095452 article EN cc-by Frontiers in Pediatrics 2023-02-03

Objective To study the pulmonary toxicity to rats induced by different sized SiO2 particles. Methods One hundred and five male SD were divided into seven groups randomly according their weight. Experimental exposed 20, 50, 80, 140, 280 800 nm particles at dose of 400 mg/m3 inhalation for 2 hours respectively. The control group was without At 24 th, 48 72 th hour after exposure, sacrificed each time point total cellular scores , protein, lactate dehydrogenase(LDH) in BALF histopathological...

10.3760/cma.j.issn.1001-9391.2010.07.008 article EN 2010-07-01

Amifostine is a cytoprotective agent against ionizing radiation-induced hematopoietic damages although the intravenous injection of amifostine unique way and administration time strictly restricted. Here we developed an amifostine-loaded dissolving armored microneedle (AAMN) patch with long-term prevention injury. Amifostine-loaded hyaluronic acid microneedles (AMNs) were fabricated, dipped in N-vinyl-2-pyrrolidone (NVP) solutions then UV irradiated to obtain AAMNs. The nail-shaped AAMNs had...

10.2139/ssrn.3539215 article EN SSRN Electronic Journal 2020-01-01

Objective To compare the egicacy and security of intracoronary administration tirofiban combined high-dose adenosine during percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (STEMI).Methods Eighty-eight cases STEMI were randomly divided into observation group(44 cases) who accepted 2 times adenosine(2 mg,10 ml 0.9% NaCl),and control afforded only 10 NaCl by prospective,double-blind,and random study.The two groups received10 g/kg after aspiration catheter...

10.3760/cma.j.issn.1008-6315.2014.12.012 article EN 中国综合临床 2014-12-01

Lung adenocarcinoma (LUAD) is a complex disease with unclear molecular characteristics. In this study, comprehensive computer analysis of genomic data was used to investigate the characteristics LUAD subtypes based on angiogenic genes. Non-negative matrix factorization (NMF) clustering performed using 1297 genes related angiogenesis. Two (C1 and C2) were found different survival times in-depth analysis. The novel classification shows that proportion immune cells CD247 expression higher in C1...

10.22541/au.169199837.76119671/v1 preprint EN cc-by Authorea (Authorea) 2023-08-14
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