Alper Akçalı

ORCID: 0000-0003-0325-886X
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About
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Research Areas
  • Food Safety and Hygiene
  • Herpesvirus Infections and Treatments
  • Antibiotic Resistance in Bacteria
  • Viral gastroenteritis research and epidemiology
  • Essential Oils and Antimicrobial Activity
  • Viral Infections and Vectors
  • Hepatitis Viruses Studies and Epidemiology
  • Listeria monocytogenes in Food Safety
  • Bacterial biofilms and quorum sensing
  • Sinusitis and nasal conditions
  • Ocular Infections and Treatments
  • Antibiotics Pharmacokinetics and Efficacy
  • Antimicrobial Peptides and Activities
  • Hepatitis B Virus Studies
  • Infections and bacterial resistance
  • Protein Hydrolysis and Bioactive Peptides
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Nasolacrimal Duct Obstruction Treatments
  • Mosquito-borne diseases and control
  • Animal Virus Infections Studies
  • COVID-19 diagnosis using AI
  • Vector-borne infectious diseases
  • COVID-19 Clinical Research Studies
  • Salmonella and Campylobacter epidemiology
  • Toxoplasma gondii Research Studies

Çanakkale Onsekiz Mart Üniversitesi
2012-2024

State Hospital
2024

Gaziantep University
2016

Canakkale Onsekiz Mart Universitesi Tip Fakultesi Hastanesi
2014

In this study, the sera collected from a variety of mammalian species (ass-mules, cat, cattle, dog, horse, human and sheep) in 10 representative provinces Turkey, were surveyed for presence neutralizing antibodies to West Nile virus (WNV). Overall, 1 40 (2.5%) ass-mules, 4 100 (4%) 43 114 (37.7%) dogs, 35 259 (13.5%) horses, 18 88 (20.4%) humans (1%) sheep, tested positive WNV-neutralizing antibodies. The results indicate that wide range mammals are exposed Nile-related could contribute...

10.1017/s0950268805005492 article EN Epidemiology and Infection 2005-11-29

Carbapenem-resistant Acinetobacter baumannii is an important cause of nosocomial infections, particularly in patients the intensive care units. As chronic infections are difficult to treat, attempts have been made discover new antimicrobials. Ceragenins, designed mimic activities antimicrobial peptides, a class agents. In this study, vitro CSA-13 either alone or combination with colistin (sulphate), tobramycin, and ciprofloxacin were investigated using 60 carbapenem-resistant A. strains...

10.1155/2014/710273 article EN BioMed Research International 2014-01-01

ABSTRACT Halloysite nanotube (HNT), a natural clay, was modified with branched polyethyleneimine (PEI) to form PEI‐HNT using epichlorohydrin (ECH) as coupling agent, then protonated HCl obtain H‐PEI‐HNTs providing [NH 3 ] + [Cl] − functionality for potential antimicrobial properties. Upon PEI modification, zeta value of HNTs increased +37.3 mV from −34.5 and +41.1 H‐PEI‐HNTs. Only 1.87 wt % H‐element in HNT 3.03 upon modification along newly generated elements N C at 2.99 9.93 %,...

10.1002/app.48352 article EN Journal of Applied Polymer Science 2019-08-05

Aim: The coronavirus disease (COVID-19) has led to over 200,000,000 confirmed cases and 4,250,000 deaths worldwide. present study aimed explore the links between epidemiological, clinical, biochemical, microbiological, radiological data treatment responses of inpatients with COVID-19 pneumonia. 
 Material Method: included 131 patients hospitalized for Laboratory values ​​such as complete blood count, coagulation profile, AST, LDH, sedimentation, CRP, BUN, creatinine, D-dimer were...

10.32322/jhsm.1035790 article EN cc-by-nc-nd Journal of Health Sciences and Medicine 2022-03-15

Purpose. The aim of the study was isolation adenoviruses by cell culture and identification using polymerase chain reaction (PCR) phylogenetic analyses in patients clinically diagnosed with viral conjunctivitis Ankara, Turkey. Methods. Conjunctival swabs from 34 acute were tested PCR for adenovirus detection. PCR-positive samples sequenced typed. Results. positive results 26.5% (9 34) method 20.6% isolation. Nine at identified as human 8 (HAdV-8) (4 9), HAdV-3 (3 HAdV-4 (1 HAdV-B 9)....

10.1177/112067211002000404 article EN European Journal of Ophthalmology 2010-07-01

There are insufficient data in the literature on presence of Helicobacter pylori tonsil and adenoid tissue patients with only airway obstruction. This study examined H. surgical cases obstruction or recurrent infection.To investigate relationship between adenotonsillar colonisation frequency adenotonsillitis to compare paediatric adult according tonsillar colonisation.Prospective clinical trial.PATIENTS SCHEDULED FOR ADENOIDECTOMY OR TONSILLECTOMY WERE CLASSIFIED INTO THREE GROUPS BASED ON...

10.5152/balkanmedj.2013.8585 article EN cc-by-nc-nd Balkan Medical Journal 2013-09-10

Urotensin-II (U-II) is a peptide recognized by its potent vasoconstrictor activity in many vascular events, however the role of urotensin-II migraine has not been considered yet. The molecular mechanisms and genetics have fully clarified yet, but it well-known that changes considerably contribute pathophysiology also complications. aim this study was to analyze plasma U-II levels along with genotype distributions allele frequencies for UTS2 Thr21Met Ser89Asn polymorphisms among patients...

10.1186/s10194-016-0623-z article EN cc-by The Journal of Headache and Pain 2016-04-18

Introduction. Colistin is a last-resort antibiotic used against carbapenem-resistant Acinetobacter baumannii (AB); however, colistin resistance has been reported recently. Methylene blue (MB) in microbiology for staining, and medicine as an antidote drug.Aim. We aimed to investigate the antimicrobial effects of MB eosin methylene (EMB) agar colistin-resistant AB strains.Methodology. Firstly, standard strain clinical isolate were included study. After determining MICs, two strains transformed...

10.1099/jmm.0.001078 article EN Journal of Medical Microbiology 2019-09-24

Aspergillus species have been implicated in a wide variety of primary ocular conditions, characterized by either slow and asymptomatic infection, or rapid, uncontrollable progression sometimes death. The study design is case series including chronic dacryocystitis, dacryocystitis with dacryoliths endogenous endophthalmitis. Due to this variable clinical presentation aspergillosis high level suspicion must be maintained as fulminant may lead rapidly progressive infection which result

10.1016/j.mmcr.2012.06.002 article EN cc-by-nc-nd Medical Mycology Case Reports 2012-01-01

Objectives. We examined IgG antibody seroprevalence and risk factors for anti-Toxoplasma gondii anti-Borrelia sp. in schizophrenic patients. Methods. This case–control study included 30 patients 60 healthy individuals. Serological analyses were identified by using ELISA technique. Results. In the case group Toxoplasma seropositivity was 33.3% Borrelia 13.3%, while control positivity 21.7% 15.0%. There no significant difference with regard to between groups (P = 0.232; P 0.832, respectively)....

10.3109/15622975.2015.1012224 article EN The World Journal of Biological Psychiatry 2015-03-16

A 40-year-old woman with a history of recurrent attacks dacryocystitis for 2 years developed lacrimal sac abscess. β-Lactam antibiotics, considered the first-line treatment dacryocystitis, were ineffective. She underwent dacryocystorhinostomy. Cultures from demonstrated presence Stenotrophomonas maltophilia and methicillin-sensitive Staphylococcus aureus , both which are sensitive to trimethoprim-sulfamethoxazole. This rare antibiotic-resistant bacterial species should be in atypical cases...

10.1136/bcr-2014-203642 article EN BMJ Case Reports 2014-06-20

Staphylococcal food poisoning (SFP) occurs by ingestion of containing enterotoxins produced enterotoxigenic staphylococci strains mainly Staphylococcus aureus.It is one the important intoxications and common all over world.When protein rich cooked foods will be contaminated with S. aureus, bacteria can grown rapidly in appropriate environmental conditions.Staphylococcal

10.5505/turkhijyen.2015.21704 article EN Turkish Bulletin of Hygiene and Experimental Biology 2015-01-01

We report the first case, in Medline-based literature, of conjunctivitis caused by gram negative diplococcus, Neisseria sicca. Although it is not widely accepted as such, isolation from cultures repeated eye swab samples suggests that N. sicca may be a pathogen conjunctival infections. Positive culture for this organism should readily dismissed. Such responded favorably to treatment with netilmicin drops.

10.4103/0301-4738.98894 article EN cc-by-nc-sa Indian Journal of Ophthalmology 2014-01-01

We investigated whether the maxillary sinus plays a stimulatory role in nasal nitric oxide (NO) synthesis. Research on sinusitis and polyps has found low NO levels exhaled air linked this to obstruction of ostium. However, major source is thought be mucosa. In study, Streptococcus pneumoniae was applied investigate changes synthesis mucosa.An experimental study performed with New Zealand white rabbits. Three groups, pneumococcus, control sham, were created. The pneumococcal group exposed...

10.4193/rhino12.081 article EN Rhinology Journal 2012-12-01
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