Although depression is highly comorbid with substance use disorders, little known about the clinical course and outcomes of methamphetamine (MA) users depressive symptoms syndromes. In this study MA-dependent individuals entering psychosocial treatment, we predicted that (1) would decline during an effect vary as a function MA (2) diagnoses post-treatment be associated poorer outcomes. Participants (N = 526) were assessed for depression, use, at baseline, treatment discharge, 3-year...

Abstract Introduction and Aims. Although psychiatric symptoms are frequently observed in methamphetamine (MA) users, little is known about the prevalence of disorders MA‐dependent individuals. This first study to examine association with substance use psychosocial functioning a large sample MA users 3 years after treatment. We predicted that diagnoses severity would be associated poorer overall over year post‐treatment course. Design Methods. Participants ( N = 526) received treatment for...

In a randomized trial, this study compared the longitudinal outcome patterns of veterans (N = 66) with substance use disorders and major depressive disorder receiving standard pharmacotherapy either 12-Step Facilitation Therapy (TSF) or disorder-specific Integrated Cognitive Behavioral Treatment (ICBT). Depression were assessed at intake, during after treatment using Hamilton Rating Scale Time Line Follow Back. Reductions in depression comparable between two groups; however, their...

Although anxiety is one of the most prominent psychiatric complaints methamphetamine (MA) users, little known about association between disorders and treatment outcomes in this population. Using data from 526 adults largest psychosocial clinical trial MA users conducted to date, study examined psychiatric, substance use, functional with concomitant 3 years after treatment. Anxiety were associated poorer alcohol drug use outcomes, increased health service utilization, higher levels...

<sec> <title>UNSTRUCTURED</title> There are a myriad of obstacles faced by individuals who take medication for opioid use disorder (MOUD), including high out-of-pocket costs, stigma, logistical challenges associated with traveling to treatment facilities, and negative experiences providers. The proliferation illicit fentanyl overdose risk underscores the urgent need broaden access lifesaving pharmacotherapy disorder. This case report describes safe effective induction 32-year-old male onto...

The purpose of this study was to identify risk factors for suicide attempts (SA) in methamphetamine (MA)‐dependent patients. MA‐dependent adults (N = 526) who participated the Methamphetamine Treatment Project were interviewed before and three years after treatment. Baseline psychiatric, medical, demographic, substance use characteristics assessed using Addiction Severity Index Beck Depression Inventory (BDI). Lifetime history SA at follow‐up. Risk included gender, intravenous MA use, BDI...

The association between alcohol use and sleep problems is well established clinically meaningful, particularly as predictors of relapse. This study aims to elucidate the relationship disturbances in a non-treatment-seeking community sample using an alcoholism problem severity factor. Participants were drinkers (N = 295) from Los Angeles who had breath content (BrAC) 0.00 g/dl when they completed in-person assessment battery comprised measures quality, anxiety depression, cigarette smoking,...

Objective: In a population of veterans with co-occurring substance use disorders and concomitant major depressive disorder, the current study compared mechanisms change therapeutic effects relevant to both between integrated, dual disorder-specific cognitive behavioral therapy (ICBT) twelve-step facilitation (TSF). Method: Veterans (N = 148) were given standard pharmacotherapy for depression randomly assigned receive 24 weeks either TSF or ICBT. Process measures selected quantify (1) changes...

Little is known about risk factors for depression in methamphetamine users. Using data from 526 adults the largest psychosocial clinical trial of users conducted to date, this study examined clinical, demographic, and substance use characteristics that predict presence a diagnosis major depressive disorder (MDD) three years after treatment dependence. The results indicate two MDD: Beck Depression Inventory total score greater than 20, one or more prior suicide attempts. These identify who...

Although weight loss is among the most commonly cited reasons for using methamphetamine (MA), little known about association between eating disorders and treatment outcomes in this population. This study examined psychiatric, substance use, functional of MA users (N = 526) with bulimia nervosa 3 years after dependence. Bulimia was observed 2.4% 13) participants associated poorer use outcomes, increased health service utilization, higher levels impairment. Addressing adults may be helpful as...

Methamphetamine (MA) users often have substantial psychiatric comorbidities, with nearly a third reporting lifetime mood disorders and over quarter anxiety disorders. Female MA are more likely to endorse depression symptoms compared men. Craving has been related mood/anxiety in users. To extend the literature on sex differences use disorder, present study examines role of as moderator relationship between craving.Participants (N = 203) were nontreatment-seeking, current users, recruited from...

Although trauma is a well-established risk factor for substance use disorders, little known about the association between posttraumatic stress disorder (PTSD) and treatment outcomes among methamphetamine users. In present study, we examine relationship PTSD post-treatment outcomes, hospitalizations, overall psychiatric impairment.Using data from 526 adults in largest psychosocial clinical trial of users conducted to date, this study examined: (1) with concomitant three years after...

: Medical conditions in methamphetamine (MA) users have not been well characterized. Using both self-report and physical examination data, the aims of this study were to (1) describe frequency medical a sample MA 3 years posttreatment; (2) evaluate association between use frequency; (3) examine relationship route administration with outcomes.: MA-dependent adults (N = 301) who participated Methamphetamine Treatment Project interviewed examined after treatment. Medical, demographic, substance...

Background: Evidence-based psychosocial interventions for addictions and related conditions such as cognitive behavioral therapy (CBT) are underutilized. Obstacles to implementation of CBT in clinical settings include limited availability quality training, supervision, certification clinicians; high rates clinician turnover caseloads; qualifications the workforce facilitate expertise. Objective: Mobile phone–based delivery CBT, if demonstrated be feasible effective, could transformative...

Substance abuse continues to be a major source of morbidity and mortality around the world. Preclinical research on substance focus determining neurobiological substrates underlying this disorder using information develop new more efficacious treatment strategies. Studying drug self-administration in laboratory animals is powerful approach with clear-cut dynamic links between preclinical findings humans. It has been will continue valuable procedure for developing pharmacological...