- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Viral gastroenteritis research and epidemiology
- Obesity and Health Practices
- Child and Adolescent Health
- Erythrocyte Function and Pathophysiology
- Obesity, Physical Activity, Diet
- Infectious Diseases and Tuberculosis
- Bone and Joint Diseases
- Sarcoma Diagnosis and Treatment
- Sexual Differentiation and Disorders
- Hepatitis Viruses Studies and Epidemiology
- Testicular diseases and treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Viral Infections and Immunology Research
- Healthcare cost, quality, practices
- Congenital Anomalies and Fetal Surgery
- Trace Elements in Health
- Cerebral Palsy and Movement Disorders
- Parasitic Diseases Research and Treatment
- Infectious Diseases and Mycology
- Medical Imaging and Pathology Studies
- Spondyloarthritis Studies and Treatments
- Pericarditis and Cardiac Tamponade
Azienda Ospedaliera S.Giuseppe Moscati
2017-2024
Ospedale Antonio Cardarelli
2016
Azienda Ospedaliera G.Rummo
2015
University of Ferrara
2009-2014
Clínica Santa María
2010
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
2008
Background It has been repeatedly reported that female patients with thalassemia major survive longer than males and the difference is due to a lower rate of cardiac disease in females.Design Methods We compared iron load as measured by T2* magnetic resonance imaging 776 (370 males) examined at National Research Council part an Italian cooperative study. also established normal left ventricular ejection fraction values for our population.Results The prevalence was higher females (105 versus...
The severity of thalassemia intermedia depends on the degree imbalance between alpha and non-alpha chains as well other genetic environmental factors that modify natural history disease. By definition, patients spontaneously maintain hemoglobin at or above 7 g/dL, sometimes price intense hyperplasia bone marrow is in turn responsible for deformities, osteoporosis, extramedullary erythropoietic masses often characterize intermedia. Transfusion may become necessary with advancing age, during...
Sickle cell disease is the commonest haemoglobinopathy in Africa, Middle East and India. In recent years, its incidence has increased dramatically also Europe North America because of high rate migration people from endemic areas. From January 2009 to 2010 number foreign residents province Ferrara (Italy) by 12.2%: most immigrants were countries at risk sickle disease. Since neonatal screening prophylactic penicillin early childhood could reduce mortality 10 years age less than 2%, aim this...
Abstract Classical Poland Syndrome (PS) is characterized by unilateral, partial or complete absence of the sternocostal head major pectoral muscle and brachysyndactyly fingers on same side. We report case a newborn infant with dextrocardia PS located left This association very rare: to date only 19 cases have been described in scientific literature. In all reported cases, as present, defect involved side was associated rib defects, whereas most are right few defects. supports view that...
Non-transfusion-dependent thalassemia includes a variety of phenotypes and genotypes that rarely require regular transfusions. However, these patients can experience wide range complications. The objective this retrospective study was to verify whether there is significant difference in non-transfusion-dependent thalassemia-related complications treatment among males females.We performed re-analysis samples evaluated previously published cross-sectional study, regarding 96 followed at the...
Abstract: The increased survival and lifespan of thalassemia patients, in the setting better iron overload monitoring chelation, have also however incidence diseases complications, which were less likely to develop. Among these, one most worrying recent years is hepatocellular carcinoma (HCC). Due blood transfusions, many patients with are or been infected hepatitis C virus (HCV) B (HBV), especially those born before 1990s countries universal HBV vaccination safe programs still not...
Abstract Childhood obesity has spread worldwide, it is on the rise, starts earlier and more severe, despite all treatment attempts. According to recent studies, weight stigma a factor that can hinder success of therapies. Healthcare workers, mainly paediatricians, need feel urgency anti-stigma training. The use non-stigmatizing terminologies images in various areas (school, sports clubs, healthcare, media, society general) improve disease management.
Two premature twins (33 weeks gestation) were born to a woman who had used paroxetine during pregnancy for an anxiety-depression disorder. They admitted the NICU, where they showed prolonged RDS, cardiovascular malformations, and facial dysmorphisms. Soon after birth, also presented abnormal neurobehavioral motor signs, which partially disappeared following weeks, although alterations of tone persisted even at discharge. Selective serotonin reuptake inhibitor (SSRI) antidepressants are...
Transfusion dependency determines iron overload in thalassaemia major, with devastating complications. Significant liver has been observed from early childhood and we aimed to evaluate factors that could predict at the first magnetic resonance imaging (MRI).All transfusion-dependent children who underwent MRI assess were retrospectively studied. Age, weight, height, blood requirement, chelation drug dosage, serum ferritin enzymes evaluated three specific steps: start of transfusion regimen,...