Ryo Okubo

ORCID: 0000-0003-0334-9745
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Cerebrovascular and Carotid Artery Diseases
  • Acute Myocardial Infarction Research
  • Maternal Mental Health During Pregnancy and Postpartum
  • Peripheral Artery Disease Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Disease and Adiposity
  • Child and Adolescent Psychosocial and Emotional Development
  • Attachment and Relationship Dynamics
  • Advanced X-ray and CT Imaging
  • Cardiovascular Function and Risk Factors
  • Cardiac Valve Diseases and Treatments
  • Child Abuse and Trauma
  • Fatty Acid Research and Health
  • Homicide, Infanticide, and Child Abuse
  • Heart Rate Variability and Autonomic Control
  • Venous Thromboembolism Diagnosis and Management
  • Suicide and Self-Harm Studies
  • Family Support in Illness
  • Heart rate and cardiovascular health
  • Complementary and Alternative Medicine Studies
  • Esophageal Cancer Research and Treatment
  • Health disparities and outcomes

National Hospital Organization
2023-2024

Obihiro National Hospital
2022-2024

Toho University
2015-2024

Toho University Omori Medical Center
2023-2024

Akita University
2024

National Center of Neurology and Psychiatry
2022

Hokkaido University
2022

Abstract This study aimed to verify whether an eHealth-based self-management program can reduce irritable bowel syndrome (IBS) symptom severity. An open-label simple randomized controlled trial was conducted that compared intervention group (n = 21) participating in eHealth program, which involved studying IBS-related information from established self-help guide followed by in-built quizzes, with a treatment-as-usual 19) that, except for pharmacotherapy, had no treatment restrictions....

10.1038/s41598-023-50293-z article EN cc-by Scientific Reports 2024-01-03

Omega-3 polyunsaturated fatty acids (PUFAs) are essential nutrients demonstrated to have health benefits, such as decreasing the risk of coronary heart disease, improving parameters associated with metabolic syndrome, and anxiety symptoms depression risk. Previous intervention studies indicated association between blood or tissue PUFA levels gut microbiota; however, details remain incompletely elucidated. We conducted a cross-sectional study examine PUFAs microbiota among breast cancer...

10.3920/bm2019.0034 article EN Beneficial Microbes 2019-09-16

Artificial intelligence quantitative CT (AI-QCT) determines coronary plaque morphology with high efficiency and accuracy. Yet, its performance to quantify lipid-rich remains unclear. This study investigated the of AI-QCT for detection low-density noncalcified (LD-NCP) using near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS).The INVICTUS Registry is a multi-center registry enrolling patients undergoing clinically indicated angiography IVUS, NIRS-IVUS, or optical coherence...

10.1016/j.atherosclerosis.2023.117363 article EN cc-by-nc-nd Atherosclerosis 2023-10-29

It has been reported that coronary vasa vasorum is associated with plaque vulnerability, and low-echoic structures in grayscale intravascular ultrasound (IVUS) are consistent pathologically vasorum. However, the association of composition no-reflow phenomenon during percutaneous intervention (PCI) unclear. We investigated virtual histology IVUS (VH-IVUS) PCI structures.A total 106 lesions being treated by VH-IVUS before were included this study. Low-echoic structure was defined as a small...

10.1536/ihj.15-373 article EN International Heart Journal 2016-01-01

Objectives We assessed the relation between coronary plaque composition and angiographic calcification by using virtual histology intravascular ultrasound (VH‐IVUS). Background The vulnerability according to is unclear. Methods Subjects were 140 consecutive patients (145 lesions) undergoing VH‐IVUS before percutaneous intervention. divided into 4 groups: no group (n = 27), spotty 65) that had calcium deposits under 90° in grayscale IVUS, intermediate 37) with or more 180°, extensive 16) 180°...

10.1111/joic.12189 article EN Journal of Interventional Cardiology 2015-04-01

Abstract Background Health literacy (HL) has gained increasing attention as a factor related to health behaviors and outcomes. This study aimed investigate geographic differences in HL levels effect modification by area on their relationship with self-rated the Japanese population using nationwide sample. Methods Data for this were derived from nationally representative cross-sectional survey information access consumers Japan mailed self-administered questionnaire 2020 (INFORM Study 2020)....

10.1186/s12889-023-15897-0 article EN cc-by BMC Public Health 2023-05-25

The progression of renal dysfunction reduces serum albumin and deteriorates the binding capacity protein-bound uremic toxins. We evaluated prognostic implications indoxyl sulfate (IS) levels in patients with cardiovascular disease.We prospectively enrolled 351 consecutive undergoing percutaneous revascularization for coronary artery disease or peripheral disease. primary endpoint was all-cause mortality. Patients were assigned to four groups according median IS (0.1 mg/dL) (3.9 g/dL).During...

10.1536/ihj.18-116 article EN International Heart Journal 2018-11-19

Since gastric cancers (GCs) detected after Helicobacter pylori (HP) eradication present with different morphological characteristics from conventional HP-positive GCs, delayed detection of early-stage GCs may be observed. This study aimed to investigate the clinical impact HP on diagnosing GC during screening endoscopy. Eleven health checkup institutions in Japan participated study. All cases newly diagnosed by endoscopy between January 2016 and December 2020 were included. After propensity...

10.3390/cancers16040733 article EN Cancers 2024-02-09
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