A5022302441- Gut microbiota and health
- Diet and metabolism studies
- Tryptophan and brain disorders
- Infant Health and Development
- Intensive Care Unit Cognitive Disorders
- Viral gastroenteritis research and epidemiology
- Fatty Acid Research and Health
- Animal Virus Infections Studies
- Gastrointestinal motility and disorders
- Neuroendocrine regulation and behavior
- Probiotics and Fermented Foods
- Colorectal Cancer Screening and Detection
- Microbial Metabolites in Food Biotechnology
- Food Safety and Hygiene
- Digestive system and related health
- Neurological Disease Mechanisms and Treatments
- Metabolism and Genetic Disorders
- Infant Nutrition and Health
- Viral Infections and Immunology Research
- Menstrual Health and Disorders
- Nutritional Studies and Diet
- Clostridium difficile and Clostridium perfringens research
- Helicobacter pylori-related gastroenterology studies
- Pediatric health and respiratory diseases
- Contact Dermatitis and Allergies
Morinaga (Japan)
2007-2022
Juntendo University
2022
Megmilk Snow Brand (Japan)
2018-2022
National Institute of Infectious Diseases
2021
Niigata University
2021
Ihara Chemical Industry (Japan)
2019
Probiotics use has been associated with modulation of inflammation and considered as a possible intervention for CNS diseases such mild cognitive impairment (MCI) dementia.We aimed to test the effect probiotic strain, Bifidobacterium breve A1 (MCC1274), restore cognition in physically healthy, suspected MCI population.In this randomized, double-blind, placebo-controlled trial, 80 healthy older adults suffering from were divided into two even groups receive once daily either (B. A1, 2×1010...
Background: Probiotics have been reported to ameliorate cognitive impairment. Objective: We investigated the effect of probiotic strain Bifidobacterium breve MCC1274 (A1) in enhancing cognition and preventing brain atrophy older patients with mild impairment (MCI). Methods: In this RCT, 130 aged from 65 88 years old suspected MCI received once daily either (B. MCC1274, 2×1010 CFU) or placebo for 24 weeks. Cognitive functions were assessed by ADAS-Jcog MMSE tests. Participants underwent MRI...
INTRODUCTION: Few reports exist regarding the therapeutic effects of probiotics on chronic constipation in elderly individuals. This study evaluated Bifidobacterium longum BB536 individuals with constipation. METHODS: was a randomized, double-blind placebo-controlled, parallel-group superiority trial Japan (UMIN 000033031). Eighty older adults diagnosed were randomly assigned (1:1) to receive either ( B. BB536, 5 × 10 colony-forming unit, n = 39) or placebo (n 41) once daily for up 4 weeks....
Omega-3 polyunsaturated fatty acids (PUFAs) are essential nutrients demonstrated to have health benefits, such as decreasing the risk of coronary heart disease, improving parameters associated with metabolic syndrome, and anxiety symptoms depression risk. Previous intervention studies indicated association between blood or tissue PUFA levels gut microbiota; however, details remain incompletely elucidated. We conducted a cross-sectional study examine PUFAs microbiota among breast cancer...
A recent meta-analysis found that probiotics have moderate-to-large beneficial effects on depressive symptoms in patients with psychiatric disorders. However, it remains unclear how the baseline gut microbiota before probiotic administration influences host’s response to probiotics. Therefore, we aimed determine whether predicted functional profile of effectiveness treatment schizophrenia. total 29 schizophrenia consumed Bifidobacterium breve A-1 (synonym B. MCC1274) for 4 weeks. We...
Bifidobacteria are one of the most abundant bacterial groups in infant gut microbiota and closely associated with health can potentially affect later life. However, details regarding source bifidobacteria have yet to be completely elucidated. This study aimed assess neonatal oral fluid (OF) as a transmission route for during delivery. Neonatal OF feces (IF) were collected immediately month after birth from 15 healthy vaginally delivered newborns. Bifidobacterium strains isolated IF samples,...
Research questionDo gut microbiota associate with the ovulatory cycle in women showing normogonadotrophic anovulation? In humans, affects diverse physiological functions and dysbiosis (microbial imbalance) may lead to pathological syndromes. However, there is comparatively little information on relevance of reproductive women. Here, a group idiopathic chronic anovulation were examined, who do not exhibit any apparent endocrinological disorder, as they are suitable for investigating...
Abstract Background Recently, the gut‐brain axis has received a lot of attention as some probiotics have been reported to beneficial effect on CNS diseases. Our previous studies show that probiotic strain, Bifidobacterium breve MCC1274 (synonym B. A1), improves memory scores in Alzheimer’s disease model and human subjects with self‐reported complaints. Furthermore, trial healthy adults MCI (Mild Cognitive Impairment), we found significantly improved cognitive function [1]. In present study,...
Dysfunctional processing of fear memory may be involved in the pathophysiology cancer recurrence (FCR), which is cited as major unmet psychological need survivors. Emerging evidence has shown that microbiota-gut-brain (MGB) axis affects psychiatric disorders, including depressive and anxiety are associated with (PMID: 29628046). We therefore hypothesized gut microbiota FCR survivors This cross-sectional study enrolled women diagnosed invasive breast who were not currently undergoing...
Background: Bifidobacteria are one of the most abundant bacterial groups in infant gut microbiota and closely associated with health as well potentially affecting later life. The establishment bifidobacteria occurs from birth is influenced by factors such mode, type feeding, antibiotic use. However, details regarding source have yet to be completely elucidated. This study aimed assess neonatal oral fluid (OF) a transmission route for during delivery. Methods: Neonatal OF fecal (IF) samples...
Noroviruses (NoVs) are the leading cause of acute epidemic gastroenteritis in worldwide.Because extensive damages health and economics, development effective vaccines is strongly desired.Virus-like particles (VLPs) which self-assembled recombinantly expressed norovirus VP1 protein made as first generation vaccine candidate against norovirus.Since noroviruses known to infect through mucosal surface, induction IgA Abs by vaccination thought be beneficial provide more immunity.In this study, we...