A5011765223- Fatty Acid Research and Health
- Diet and metabolism studies
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Eicosanoids and Hypertension Pharmacology
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Air Quality and Health Impacts
- Breastfeeding Practices and Influences
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Anesthesia and Neurotoxicity Research
- Child Nutrition and Feeding Issues
- Posttraumatic Stress Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Pancreatic and Hepatic Oncology Research
- Stress Responses and Cortisol
- Alcoholism and Thiamine Deficiency
- Metabolomics and Mass Spectrometry Studies
- Cancer, Lipids, and Metabolism
- Climate Change and Health Impacts
- Liver Disease and Transplantation
- Vitamin D Research Studies
- Peroxisome Proliferator-Activated Receptors
- Cholangiocarcinoma and Gallbladder Cancer Studies
University of Toyama
2015-2024
Gunma University
2021-2024
Faculty of Public Health
2021
Japan Science and Technology Agency
2010-2016
RIKEN Center for Brain Science
2010-2016
National Center of Neurology and Psychiatry
2014-2015
National Institutes of Health
2009-2013
National Institute on Alcohol Abuse and Alcoholism
2009-2010
Toho University
2008
Toho University Ohashi Medical Center
2008
Matrix-assisted laser desorption ionization/ionization imaging mass spectrometry (MALDI IMS) with a time-of-flight analyzer was used to characterize the distribution of lipid molecular species in brain rats two injury models. Ischemia/reperfusion rat after bilateral occlusion carotid artery altered appearance phospholipids present hippocampal region, specifically CA1 region. These regions also had large increase ion abundance at m/z 548.5 and collisional activation supported identification...
Abstract Background Lower socioeconomic status is often thought to be associated with an elevated risk of postpartum depression; however, this relationship exhibits noticeable heterogeneity between studies. The present study examined in Japan. Methods Data were obtained from 90,194 mothers ongoing birth cohort the Japan Environment and Children’s Study. Socioeconomic was assessed based on mothers’ highest education level during pregnancy. Postpartum depression identified at 1 6 months...
Systematic review of observational studies has revealed that fish consumption and levels n-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) docosahexaenoic are associated with a reduced risk depression. A reverse J-shaped effect PUFAs was suggested. However, there is limited evidence from populations high no have used standard psychiatrist-based diagnosis major depressive disorder (MDD). Therefore, this population-based, prospective study investigated the association...
Abstract The risk of schizophrenia is increased in offspring whose mothers experience malnutrition during pregnancy. Polyunsaturated fatty acids (PUFAs) are dietary components that crucial for the structural and functional integrity neural cells, PUFA deficiency has been shown to be a factor schizophrenia. Here, we show gestational early postnatal deprivation two PUFAs—arachidonic acid (AA) docosahexaenoic (DHA)—elicited schizophrenia-like phenotypes mouse at adulthood. In PUFA-deprived...
Postpartum depression is a major mental health issue. It not only adversely affects the mother's quality of life, but also mother-infant bonding. However, relationship between postpartum (at multiple points after childbirth) and bonding failure one year birth well understood. This study investigates at 1-month 6-month 1 with large cohort.Data from 83 109 mothers Japan Environment Children's Study were analyzed. Mother-infant 1-year delivery was assessed using Mother-to-Infant Bonding Scale...
This research aimed to examine the efficacy of early initiation breastfeeding within 1 h birth, skin-to-skin contact, and rooming-in for continuation exclusive until 6 months postpartum. The used data from Japan Environment Children's Study (JECS), a nationwide government-funded birth cohort study. A total 80,491 mothers in between January 2011 March 2014 who succeeded or failed exclusively breastfeed were surveyed JECS. Multiple logistic regression model was analyse data. percentage is...
Background The Great East Japan Earthquake of March 11, 2001 left around 20,000 dead or missing. Previous studies showed that rescue workers, as well survivors, disasters are at high risk for posttraumatic stress disorder (PTSD). This study examined the predictive usefulness Peritraumatic Distress Inventory (PDI) among workers Disaster Medical Assistance Teams (DMATs) deployed during acute disaster phase Earthquake. Methodology/Principal Findings In this prospective observational study, DMAT...
On March 11, 2011, the Great East Japan Earthquake and tsunami that followed caused severe damage along Japan’s northeastern coastline to Fukushima Daiichi nuclear power plant. To date, there are few reports specifically examining psychological distress in rescue workers Japan. Moreover, it is unclear what extent concern over radiation exposure has such deployed disaster area. One month after disaster, 424 of 1816 (24%) medical assistance team area were assessed. Concern was evaluated by a...
Background The aim of this study was to examine how physical activity (PA) before and during pregnancy influences outcomes, particularly preterm delivery mode delivery. Methods This based on the Japan Environment Children's Study. A total 92,796 pregnant women who gave birth live singleton babies were included. Information mean PA per week extracted from responses questionnaires completed by second third trimesters pregnancy. obtained answered recall at participation. level stratified into...
Docosahexaenoic acid (DHA) might help prevent or attenuate posttraumatic stress disorder (PTSD) symptoms. We examined the efficacy and safety of DHA for preventing PTSD (DSM-IV) after severe accidental injury.From December 2008 to August 2013, we conducted a randomized, double-blind, placebo-controlled trial 110 accident-injured patients consecutively admitted an intensive care unit National Disaster Medical Center in Tokyo, Japan. All were taught about their psychological reactions injury...
The results of several epidemiological studies have shown a moderate association between postpartum depression (PPD) and mother-infant bonding (MIB); however, associations changes that longitudinally considered parity were not reported. We investigated the possible PPD MIB at one month after birth, in addition, these indices by parity. From dataset comprising 103,099 maternal registrations Japan Environment Children's Study, present study analyzed complete data on questionnaires for 76,363...
Omega-3 polyunsaturated fatty acids (PUFAs) are essential nutrients demonstrated to have health benefits, such as decreasing the risk of coronary heart disease, improving parameters associated with metabolic syndrome, and anxiety symptoms depression risk. Previous intervention studies indicated association between blood or tissue PUFA levels gut microbiota; however, details remain incompletely elucidated. We conducted a cross-sectional study examine PUFAs microbiota among breast cancer...
Background As a consequence of indoor occupations and reduced exposure to sunlight, concerns have been raised that vitamin D deficiency is widespread in developed countries. Vitamin known be associated with increased risks morbidity mortality various diseases. Objective To investigate the serum status its relation life-style factors pregnant Japanese women. Methods Among cohort for 3,327 women who participated an adjunct study Japan Environment Children's Study during 2011–2013, which data...