Kathrine Kronberg Jakobsen

ORCID: 0000-0003-0336-5411
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About
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Research Areas
  • Head and Neck Cancer Studies
  • Cervical Cancer and HPV Research
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Treatments and Mutations
  • Molecular Biology Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Oral Health Pathology and Treatment
  • SARS-CoV-2 detection and testing
  • Salivary Gland Disorders and Functions
  • Head and Neck Surgical Oncology
  • Oral health in cancer treatment
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer-related molecular mechanisms research
  • Lung Cancer Diagnosis and Treatment
  • Tumors and Oncological Cases
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Diagnosis and Treatment
  • Biosensors and Analytical Detection
  • Ear and Head Tumors
  • Lung Cancer Research Studies
  • Mesenchymal stem cell research
  • Thyroid Cancer Diagnosis and Treatment
  • COVID-19 diagnosis using AI
  • Colorectal and Anal Carcinomas

Rigshospitalet
2017-2025

Copenhagen University Hospital
2020-2025

University of Copenhagen
2017-2024

Frederiksberg Hospital
2024

Capital Region of Denmark
2017

Praxis
2010

Hvidovre Hospital
1986

Oral squamous cell carcinoma (OSCC) is responsible for high morbidity and mortality worldwide. Although the oral cavity encompasses different anatomical subsites, it unclear whether subsite localization of influences outcome. This retrospective cohort study examined overall survival (OS), recurrence-free (RFS) local (L-RFS) at subsites by Kaplan-Meier curves. Cox proportional hazards regression analysis was performed to investigate impact on death, locoregional recurrence, recurrence. The...

10.1016/j.oraloncology.2024.106684 article EN cc-by Oral Oncology 2024-01-10

The purpose of the study was to determine trends in age-adjusted incidence rates (AAIR) and survival probability head neck cancers (HNCs) Danish population from 1980 2014.All patients registered with HNC nationwide Cancer Registry 2014 were included. We evaluated AAIR per 100,000 average annual percent change (AAPC). relative at 5 years calculated relation gender, anatomical location histology, we constructed age-period-cohort models incidence.About 34,606 included (64.7% men). increased 9.1...

10.1080/0284186x.2018.1438657 article EN Acta Oncologica 2018-02-15

Background: The purpose of this registry study was to evaluate trends in incidence and survival laryngeal cancer the Danish population from 1980 2014. Methods: This includes all patients with registered Cancer Registry (DCR) period 1980-2014. age-adjusted rate (AAIR) per 100,000 average annual percent change (AAPC) were calculated. We evaluated relative at five years relation gender, anatomical location, year diagnosis, histological type. Further, an age-period-cohort (APC) model...

10.1080/0284186x.2019.1572923 article EN Acta Oncologica 2019-03-01

To evaluate the accuracy of cell-free human papillomavirus-DNA (cfHPV-DNA) measurements in liquid biopsies predicting disease patients with HPV-positive/p16-positive (HPV+/p16+) oropharyngeal squamous cell carcinoma (OPSCC).This was a prospective cohort study. Plasma samples were collected before treatment, serially after curative intended therapy at follow-up visits 2 weeks, and 6, 9, 12, 18, 24, 30 months treatment. A droplet digital PCR assay comprising eight HPV genotypes used. found...

10.1158/1078-0432.ccr-23-1064 article EN Clinical Cancer Research 2023-07-21

Importance Self- or health care worker (HCW)–collected nasal swab specimens are the preferred sampling method to perform rapid antigen testing for COVID-19, but it is debated whether throat can improve test sensitivity. Objective To compare diagnostic accuracy of self- and HCW-collected vs COVID-19 testing. Design, Setting, Participants This per-protocol multicenter randomized clinical trial was conducted from February 15 through March 25, 2022. The participants, individuals aged 16 years...

10.1001/jamanetworkopen.2023.44295 article EN cc-by-nc-nd JAMA Network Open 2023-12-06

Denmark, alongside other Scandinavian countries, the United States, Canada, and Kingdom, has high prevalence of human papillomavirus (HPV). Our oropharyngeal squamous cell carcinoma (OPSCC) database includes all diagnosed cases in Eastern Denmark during a period more than two decades. We investigated incidence, survival, recurrence patients with OPSCC combined p16- HPV testing covering consecutive 21-year period. Age-adjusted incidence rate (AAIR) per 100,000, survival models, Cox...

10.1002/ijc.35099 article EN cc-by International Journal of Cancer 2024-07-17

Sinonasal cancers are rare and comprise <1% of all malignancies. This study describes incidence survival in sinonasal carcinomas Denmark from 1980 to 2014.All patients registered the Danish Cancer Registry period were included. Age-adjusted rate, average annual percentage change, relative calculated. Age-period-cohort models constructed.1,720 with carcinoma (median age 67 years, 63% males) identified. There was no significant change age-adjusted incidence; 0.70 0.43 per 100,000 2014 (p >...

10.1080/0284186x.2018.1454603 article EN Acta Oncologica 2018-03-26

&lt;div&gt;AbstractPurpose:&lt;p&gt;The long-term effect of adipose-derived mesenchymal stromal cells (ASC) on restoring radiation-induced salivary gland hypofunction in patients with previous head and neck cancer has not been validated larger settings.&lt;/p&gt;Patients Methods:&lt;p&gt;The study was a 12-month follow-up randomized trial, including hyposalivation. Patients were to receive allogeneic ASC or placebo the submandibular glands. The primary endpoint unstimulated whole saliva...

10.1158/1078-0432.c.7700604 preprint EN 2025-03-03

Abstract Background Rapid and accurate detection of SARS-CoV-2 infection is essential in limiting the spread during ongoing COVID-19 pandemic. The aim this study was to determine accuracy STANDARD Q Ag test (SD BIOSENSOR) by comparison with RT-PCR a public setting. Method Individuals aged 18 years or older who had booked an appointment for on December 26-31, 2020 at center Copenhagen, Denmark, were invited participate. An oropharyngeal swab collected analysis, immediately followed...

10.1101/2021.01.22.21250042 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-01-25
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