A5100451520- Global Maternal and Child Health
- Pregnancy and preeclampsia studies
- Esophageal Cancer Research and Treatment
- Birth, Development, and Health
- Gastrointestinal Tumor Research and Treatment
- Child Nutrition and Water Access
- Maternal and Perinatal Health Interventions
- Reproductive Biology and Fertility
- Maternal and fetal healthcare
- Folate and B Vitamins Research
- Assisted Reproductive Technology and Twin Pregnancy
- Cancer-related gene regulation
- Ovarian function and disorders
- Congenital Heart Disease Studies
- Global Health Care Issues
- Healthcare Systems and Reforms
- Health disparities and outcomes
- Esophageal and GI Pathology
- Plant Molecular Biology Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Prenatal Screening and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Neuroinflammation and Neurodegeneration Mechanisms
- Acupuncture Treatment Research Studies
Sichuan University
2016-2025
West China Second University Hospital of Sichuan University
2016-2025
Beijing Anding Hospital
2018-2025
Capital Medical University
2014-2025
Fudan University
2015-2025
Zhongshan Hospital
2024-2025
Eli Lilly (United States)
2021-2025
Anhui Normal University
2012-2025
Anhui Agricultural University
2025
Shenzhen Second People's Hospital
2025
BackgroundPublic health is a priority for the Chinese Government. Evidence-based decision making at province level in China, which home to fifth of global population, paramount importance. This analysis uses data from Global Burden Diseases, Injuries, and Risk Factors Study (GBD) 2017 help inform monitor progress on level.MethodsWe used methods GBD analyse patterns 34 province-level administrative units China 1990 2017. We estimated all-cause cause-specific mortality, years life lost (YLLs),...
Previous estimates have highlighted a large global burden of stillbirths, with an absence reliable data from regions where most stillbirths occur. The Every Newborn Action Plan (ENAP) targets national stillbirth rates (SBRs) 12 or fewer per 1000 births by 2030. We estimate SBRs and numbers for 195 countries, including trends 2000 to 2015.
The mammalian vomeronasal organ detects social information about gender, status, and individuality. molecular cues carrying this remain largely unknown. Here, we show that small peptides serve as ligands for major histocompatibility complex (MHC) class I molecules function also sensory stimuli a subset of neurons located in the basal Gao- V2R receptor–expressing zone epithelium. In behaving mice, same individuality signals underlying mate recognition context pregnancy block. MHC constitute...
<h3>Abstract</h3> <h3>Objective</h3> To examine how the relaxation of one child policy and policies to reduce caesarean section rates might have affected trends over time in perinatal pregnancy related mortality China. <h3>Design</h3> Observational study. <h3>Setting</h3> China’s National Maternal Near Miss Surveillance System (NMNMSS). <h3>Participants</h3> 6 838 582 births at 28 completed weeks or more gestation birth weight ≥1000 g 438 hospitals NMNMSS between 2012 2016. <h3>Main outcome...
China has achieved Millennium Development Goal 4 to reduce under-5 mortality rate by two-thirds between 1990 and 2015. In this study, we estimated the national subnational levels causes of child in annually from 1996 2015 draw implications for achievement SDGs other low-income middle-income countries.
BackgroundPreterm birth rates have increased significantly worldwide over the past decade. Few epidemiological studies on incidence of preterm and temporal trends are available in China. This study used national monitoring data from China's National Maternal Near Miss Surveillance System (NMNMSS) to estimate rate between 2012 2018 China assess risk factors associated with birth.MethodsIn this observational study, were sourced NMNMSS Jan 1, 2012, Dec 31, 2018. Pregnancies at least one...
Vast amounts of plastic materials are produced in the modern world and despite recycling efforts, large disposed water systems landfills. Under these storage conditions, physical weathering photochemical processes break down into smaller particles micro- nano-scale. In addition, ecosystems can be contaminated with which manufactured size ranges for commercial purposes. Independent source, microplastics abundant environment have found their way supplies food cycle where human exposure is...
Genes of the major histocompatibility complex (MHC), which play a critical role in immune recognition, influence mating preference and other social behaviors fish, mice, humans via chemical signals. The cellular molecular mechanisms by this occurs nature these chemosignals remain unclear. In contrast to widely held view that olfactory sensory neurons (OSNs) main epithelium (MOE) are stimulated volatile only, we show here nonvolatile system molecules function as cues mammalian MOE. Using mice...
Software vulnerabilities pose significant security risks to the host computing system. Faced with continuous disclosure of software vulnerabilities, system administrators must prioritize their efforts, triaging most critical address first. Many vulnerability scoring systems have been proposed, but they all require expert knowledge determine intricate metrics. In this paper, we propose a deep learning approach predict multi-class severity level using only description. Compared metrics,...
On 12 May, 2008, a devastating earthquake registering 8.0 on the Richter scale occurred in Sichuan Province, China, taking tens of thousands lives and destroying homes millions people. Many deceased were children, particular children less than five years old who more vulnerable to such huge disaster adult. In order obtain information specifically relevant further researches future preventive measures, potential risk factors associated with earthquake-related child mortality need be...
Recent studies have suggested that the etiology of autism spectrum disorder (ASD) may be caused by immunological factors, particularly abnormalities in innate immune system. However, it is still unclear which specific cytokines most importance. The current study therefore investigated showed altered concentrations blood ASD compared with healthy control children and were also correlated symptom severity. Our sample included 32 diagnosed 28 age sex-matched typically developing children....
BackgroundAs one of only a handful countries that have achieved both Millennium Development Goals (MDGs) 4 and 5, China has substantially lowered maternal mortality in the past two decades. Little is known, however, about levels trends at county level China.MethodsUsing national registration system level, we estimated ratios for 2852 counties between 1996 2015. We used state-of-the-art Bayesian small-area estimation hierarchical model with latent Gaussian layers to account space time...
Very little is known about the burden and determinants of stillbirths in China. We used data from a national surveillance system for health facility births to compute stillbirth rate representative all China explore sociodemographic obstetric factors associated with variation rate.We China's National Maternal Near Miss Surveillance System between Jan 1, 2012, Dec 31, 2014, which covers 441 hospitals 326 urban districts rural counties. The aimed enumerate maternal deaths near misses...
Abstract Alzheimer's disease (AD) is the most prevalent type of dementia, characterized by presence amyloid‐β (Aβ) plaques. We previously reported that Klotho lowered Aβ levels in brain and protected against cognitive deficits amyloid precursor protein/presenilin 1(APP/PS1) mice. However, underlying mechanism remains unclear. In this study, we induced intracerebral overexpression 13‐month‐old APP/PS1 mice injecting lentivirus carried full‐length mouse cDNA lateral ventricle brain. examined...
Among patients with a transient ischemic attack or minor strokes, those ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the highest risk recurrent vascular events.