A5048150723- Autism Spectrum Disorder Research
- Helicobacter pylori-related gastroenterology studies
- Dementia and Cognitive Impairment Research
- Child Nutrition and Feeding Issues
- Gastroesophageal reflux and treatments
- Alzheimer's disease research and treatments
- Psychological Well-being and Life Satisfaction
- Gastrointestinal Bleeding Diagnosis and Treatment
- Eosinophilic Esophagitis
- EEG and Brain-Computer Interfaces
- Machine Learning in Healthcare
- Family and Disability Support Research
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Cardiac Health and Mental Health
- Gastrointestinal motility and disorders
- Nutritional Studies and Diet
- Functional Brain Connectivity Studies
- Psychosomatic Disorders and Their Treatments
- Gastrointestinal disorders and treatments
- Cardiovascular Health and Disease Prevention
- Diet and metabolism studies
- Blood Pressure and Hypertension Studies
- Artificial Intelligence in Healthcare
Villa Maria Hospital
2018-2024
Center for Rheumatology
2024
Belmont University
2024
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo
2024
Bracco (Italy)
2012-2023
University of Pisa
2001-2023
Faculty of Public Health
2023
Semeion Centro Ricerche di Scienze della Comunicazione
2011-2021
University of Milan
1960-2021
Centro Diagnostico Italiano
2006-2020
A high prevalence of a variety gastrointestinal (GI) symptoms is frequently reported in patients with Autism Spectrum Disorders (ASD). The GI disturbances ASD might be linked to gut dysbiosis representing the observable phenotype "gut-brain axis" disruption. exploitation strategies which can restore normal microbiota and reduce production absorption toxins, such as probiotics addition/supplementation diet, may represent non-pharmacological option treatment ASD. aim this randomized controlled...
The microbiota-gut-brain axis has been recently recognized as a key modulator of neuropsychiatric health. In this framework, probiotics (recently named "psychobiotics") may modulate brain activity and function, possibly improving the behavioral profiles children with Autism Spectrum Disorder (ASD). We evaluated effects on autism in double-blind randomized, placebo-controlled trial 85 preschoolers ASD (mean age, 4.2 years; 84% boys). Participants were randomly assigned to (De Simone...
The PGWBI is a 22-item health-related Quality of Life (HRQoL) questionnaire developed in US which produces self-perceived evaluation psychological well-being expressed by summary score. has been validated and used many countries on large samples the general population specific patient groups. Recently study was carried out Italy to reduce number items original questionnaire, yielding creation shorter version (PGWB-S). purpose present paper describe methods adopted report discuss relevance...
We sought (i) to validate a new prediction rule of mortality (Progetto Nazionale Emorragia Digestiva (PNED) score) on an independent population with non-variceal upper gastrointestinal bleeding (UGIB) and (ii) compare the accuracy Italian PNED score vs. Rockall in predicting risk death.We conducted prospective validation analysis consecutive patients UGIB at 21 hospitals from 2007 2008. Outcome measure was 30-day mortality. All variables used calculate as well those identified predictive...
<h3>Importance</h3> Music therapy may facilitate skills in areas affected by autism spectrum disorder (ASD), such as social interaction and communication. <h3>Objective</h3> To evaluate effects of improvisational music on generalized communication children with ASD. <h3>Design, Setting, Participants</h3> Assessor-blinded, randomized clinical trial, conducted 9 countries enrolling aged 4 to 7 years Children were recruited from November 2011 2015, follow-up between January 2012 2016....
Human milk is essential for the initial development of newborns, as it provides all nutrients and vitamins, such vitamin D, represents a great source commensal bacteria. Here we explore microbiota network colostrum mature Italian Burundian mothers using auto contractive map (AutoCM), new methodology based on artificial neural (ANN) architecture. We were able to demonstrate human be dynamic, complex, ecosystem with different bacterial networks among populations containing diverse microbial...
Objective— To investigate whether several different measures of carotid intima-media thickness (IMT) progression are associated with subsequent vascular events and such associations independent baseline atherosclerotic profile Framingham risk factors. Approach Results— A longitudinal cohort study (the Carotid Intima Media Thickness [IMT] IMT-Progression as Predictors Vascular Events in a High Risk European Population study) was performed 7 centers 5 countries (Finland, France, Italy, the...
Autism spectrum disorder is a neurodevelopmental condition that typically displays socio-communicative impairment as well restricted stereotyped interests and activities, in which gastrointestinal disturbances are commonly reported. We report the case of boy with Spectrum Disorder (ASD) diagnosis, severe cognitive disability celiac disease an unexpected improvement autistic core symptoms was observed after four months probiotic treatment.The study refers to 12 years old ASD attending Villa...
Breast milk is a rich nutrient with temporally dynamic nature. In particular, numerous alterations in the nutritional, immunological and microbiological content occur during transition from colostrum to mature milk. The objective of our study was evaluate potential impact delivery mode on microbiota colostrum, at both quantitative qualitative levels (bacterial abundance network).Twenty-nine Italian mothers (15 vaginal deliveries vs 14 Cesarean sections) were enrolled study. samples analyzed...
Regional intravenous guanethidine blocks and stellate ganglion have been compared in a randomized trial. Nineteen patients, randomly allocated to two groups of therapy exhibiting severe reflex sympathetic dystrophy following peripheral nerve lesions, treated. The performance the block is longer duration superior block, as regards some early pharmacological effects (skin temperatures amplitude plethysmographic waves recorded before blockade 15 min, 60 24 h, 48 h after institution block). In...
The 'IMPROVE study' was designed to investigate whether cross-sectional carotid artery intima–media thickness (IMT) and overall IMT progression are predictors of new vascular events in European individuals at high risk cardiovascular diseases. This paper reports the results baseline analyses aimed identifying major determinants increased (C-IMT). IMPROVE is a prospective, multicentre, longitudinal, observational study. A total 3711 subjects (age range 54–79 years) with least three factors...
Age-related changes in nutritional status can play an important role brain functioning. Specific nutrient deficiencies the elderly may exacerbate pathological processes brain. Consequently, potential of intervention to prevent or delay cognitive impairment and development dementia is topic. A randomized, double-blind, placebo-controlled trial has been performed 25 subjects (86 ± 6 years, 20 females, 5 males) with mild (MCI). These were randomly assigned supplement their diet either oily...
To investigate factors associated with bone mineral density (BMD) in type 1 diabetes by classic statistic and artificial neural networks.A total of 175 eugonadal diabetic patients (age 32.8 ± 8.4 years) 151 age- BMI-matched control subjects 32.6 4.5 were studied. In all subjects, BMI BMD (as Z score) at the lumbar spine (LS-BMD) femur (F-BMD) measured. Daily insulin dose (DID), age diagnosis, presence complications, creatinine clearance (ClCr), HbA(1c) determined.LS- F-BMD levels lower...
Motor disturbances have been widely observed in children with autism spectrum disorder (ASD), and motor problems are currently reported as associated features supporting the diagnosis of ASD current Diagnostic Statistical Manual Mental Disorders (DSM-5). Studies on this issue different domains, including both gross fine areas well coordination, postural control, standing balance. However, they failed to clearly state whether impairments related demographical developmental ASD. Both...