A5033197898- Adenosine and Purinergic Signaling
- Tryptophan and brain disorders
- Alkaloids: synthesis and pharmacology
- Sirtuins and Resveratrol in Medicine
- Berberine and alkaloids research
- Curcumin's Biomedical Applications
- Cholinesterase and Neurodegenerative Diseases
- Neurogenesis and neuroplasticity mechanisms
- Neuroscience of respiration and sleep
- Vitamin C and Antioxidants Research
- Toxoplasma gondii Research Studies
- Gestational Diabetes Research and Management
- Vagus Nerve Stimulation Research
- Organic Light-Emitting Diodes Research
- Beetle Biology and Toxicology Studies
- Cannabis and Cannabinoid Research
- RNA Interference and Gene Delivery
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Essential Oils and Antimicrobial Activity
- melanin and skin pigmentation
- Genetic Syndromes and Imprinting
- Aluminum toxicity and tolerance in plants and animals
- Prenatal Substance Exposure Effects
- Medicinal Plants and Neuroprotection
Universidade Federal de Santa Maria
2016-2025
Abstract Pain caused by the tumor or aromatase inhibitors (AIs) is a disabling symptom in breast cancer survivors. Their mechanisms are unclear, but pro-algesic and inflammatory mediators seem to be involved. Kinins endogenous algogenic associated with various painful conditions via B 1 2 receptor activation, including chemotherapy-induced pain proliferation. We investigate involvement of kinin receptors metastatic (4T1 cells)-caused (anastrozole letrozole) therapy-associated pain. A...
Aluminum (Al) is ubiquitously present in the environment and known to be a neurotoxin for humans. The trivalent free Al anion (Al3+) can cross blood-brain barrier (BBB), accumulate brain, elicit harmful effects central nervous system (CNS) cells. Thus, evidence has suggested that increases risk of developing neurodegenerative diseases, particularly Alzheimer’s disease (AD). Purinergic signaling been shown play role several neurological conditions as it modulate functioning cell types, such...
Abstract The purinergic system has an important role in the regulation of vascular functions. interference thyroid hormones this and cardiovascular events been studied recent years. However, mechanisms involved vascular, purinergic, oxidative changes disorders are not completely understood. Therefore, present study aimed to assess enzyme activity platelets from rats with hypothyroidism hyperthyroidism induced, respectively, by continuous exposure methimazole (MMI) at 20 mg/100 mL or...
This study examined the behavioral responses, purinergic receptor densities, ectonucleotidases (E-NTPDase), adenosine deaminase (ADA) activity, and nitric oxide (NO) levels along with parameters of oxidative stress–related to erectile function in cerebral cortex (CC) L-NAME-challenged rats pretreated tigernut (TN) walnut (WN) dietary supplementation. Wistar (male) 70 total animals (250–300 g) were used this research hence separated into seven groups (n = 10): Group I: normal control-fed...
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Cancer is an important cause of lethality, and melanoma associated with less than 10% survival. The traditional treatment includes the use vinblastine, it side effects. Curcumin extracted from Curcuma longa rhizomes, studied in many diseases, producing a variety We investigated role various cellular pathways concerning apoptosis, cell cycle enzymes line SK-MEL-28, after curcumin, or combination both, for 24 hours. After this, we performed cycle, wound healing assay, comet assay on cells,...