- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Cardiovascular Health and Risk Factors
- Urinary Bladder and Prostate Research
- Birth, Development, and Health
- COVID-19 Clinical Research Studies
- Chronic Disease Management Strategies
- Cardiovascular Disease and Adiposity
- Long-Term Effects of COVID-19
- Nutrition, Genetics, and Disease
- Genetic Associations and Epidemiology
- COVID-19 epidemiological studies
- Folate and B Vitamins Research
- Acute Ischemic Stroke Management
- Pneumonia and Respiratory Infections
- Covalent Organic Framework Applications
- Enhanced Recovery After Surgery
- Neurological Disorders and Treatments
- Apelin-related biomedical research
- Cardiac Health and Mental Health
- Sleep and related disorders
- Cancer, Lipids, and Metabolism
- Hormonal and reproductive studies
- Thermoregulation and physiological responses
- Cardiovascular Health and Disease Prevention
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Zhengzhou University
2021-2024
Background Water, coffee and tea are the primary sources of daily hydration. However, sex-specific relationship between these beverages cardiovascular disease (CVD) among remains unclear. Methods In total, 210,239 men 251,383 women from UK Biobank were included. The consumption water, self-reported. CVDs, including coronary heart (CHD), stroke failure (HF) followed till March 1st, 2023. Sex-specific Cox models utilized to evaluate hazard ratios (HRs) 95% confidence intervals (CIs) for...
Background and purpose: Acute ischemic stroke (AIS) is the most prevalent type of stroke, associated with a significant burden functional impairments. About 94.2% AIS patients present multiple comorbidities, but how they affect prognosis remains largely unknown. This study aims to comprehensively assess associations wide range AIS-related their patterns, impairments in patients. Method: utilized data from China National Stroke Registry 3 (CNSR3), prospective registry encompassing 201 Chinese...
Evidence from previous epidemiological studies on the effect of physical activity risk Alzheimer's disease (AD) is conflicting. We performed a two-sample Mendelian randomization analysis to verify whether causally associated with AD. This study used (MR) estimate association between (including overall activity, sedentary behavior, walking, and moderate-intensity activity) Genetic instruments for were obtained published genome-wide (GWAS) including 91,105 individuals UK Biobank. Summary-level...
A cross-sectional study was conducted to estimate the age-stratified normal levels and age-related changes in risk predictors of benign prostatic hyperplasia (BPH) progression. total 4706 male participants aged 40 years or older Zhengzhou (China) were enrolled. The values International Prostate Symptom Score (IPSS), prostate-specific antigen (PSA), prostate volume (PV), postvoid residual urine (PVR) significantly increased with age. Nonlinear relationships between age IPSS scores ≥8 (P for...
Multimorbidity is significantly associated with life quality decline, disability, and increased mortality risk. Additionally, it leads to greater consumption of healthcare resources, presenting substantial challenges systems globally. To better assess the burden multimorbidity, its impact on patient health outcomes services, explore underlying mechanisms in development, this paper summarizes existing methods used for measuring analyzing multimorbidity research practice, including disease...
Abstract Artificial neural network (ANN) is the main tool to dig data and was inspired by human brain nervous system. Several studies clarified its application in medicine. However, none has applied ANN predict efficacy of folic acid treatment Hyperhomocysteinemia (HHcy). The been proved associate with both genetic environmental factors while previous just focused on latter one. explained variance risk score (EV-GRS) had better power could represent effect architectures. Our aim add EV-GRS...
Objective: Little is known about the effect of age at first childbirth on lung function. We aimed to investigate association between and function in Chinese women further test whether this mediated by body mass index (BMI). Methods: This cross-sectional study a partial survey China Kadoorie Biobank (CKB) which was conducted Xinxiang City, Henan Province 2004 2008. A total 16,584 postmenopausal aged 30– 79 years were enrolled. Multiple linear logistic regression used overweight/obesity. The...