A5103075750- Autophagy in Disease and Therapy
- Entomopathogenic Microorganisms in Pest Control
- Viral Infectious Diseases and Gene Expression in Insects
- Insect Resistance and Genetics
- Endometrial and Cervical Cancer Treatments
- Rheumatoid Arthritis Research and Therapies
- MicroRNA in disease regulation
- Adenosine and Purinergic Signaling
- Lymphoma Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Cancer-related Molecular Pathways
- Cervical Cancer and HPV Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune Cell Function and Interaction
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- RNA modifications and cancer
- DNA Repair Mechanisms
- Colorectal and Anal Carcinomas
- Monoclonal and Polyclonal Antibodies Research
Hubei University of Arts and Science
2022-2024
Xiangyang Central Hospital
2023-2024
University of Chinese Academy of Sciences
2019-2022
Cancer Hospital of Chinese Academy of Medical Sciences
2022
Wuhan Institute of Virology
2019
Chinese Academy of Sciences
2019
Introduction Acute respiratory distress syndrome (ARDS) is a major cause of death among critically ill patients in intensive care settings, underscoring the need to identify biomarkers capable predicting ARDS patient clinical status and prognosis at an early time point. This study specifically sought explore utility relevance TM9SF1 as biomarker for prediction disease severity prognostic outcomes with ARDS. Methods enrolled 123 severe 116 non-severe whom follow-up information was available....
Transmembrane 9 superfamily member 1 (TM9SF1) is involved in inflammation. Since both inflammatory and autoimmune diseases are linked to immune cells regulation, this study investigated the association between TM9SF1 expression disease activity. As B cell differentiation autoantibody production exacerbate disease, signaling pathways these processes were explored.
Abstract Transmembrane 9 superfamily protein member 1 (TM9SF1) has abnormal overexpression in specific clinical diseases; however, its precise role disease progression remains poorly understood. The current study revealed the critical importance of maintaining appropriate TM9SF1 levels for proper distribution FEN1, a crucial DNA repair. interacted with FEN1 through N-terminal region spanning amino acids 1-236, which could translocate into nucleus, while C-terminal segment 237–606 was...
Rheumatoid arthritis (RA) often involves an altered T-cell subpopulation, higher levels of inflammatory cytokines, and auto-antibodies. This study investigated whether PDCD5 could be a biomarker to predict the incidence remission RA so as guide therapeutic management clinical RA.One hundred fifty-two patients (41 being in both active status stable status) who were newly diagnosed with 38 healthy controls enrolled. Basic data collected before using blood samples remaining clinic after routine...
Some evidence in the literature indicated an association between members of transmembrane 9 superfamily (TM9SF) and cancer, but role TM9SF1 has remained elusive. Here, we analysed expression a mouse model acute lung injury (ALI) induced by LPS found that was significantly increased 24 h after induction ALI. knockout (TM9SF1-/-) ALI revealed up-regulation LC3 II down-regulation P62 expression. improved ALI, as evidenced survival rate, decreased seen histopathology, pulmonary vascular...
Objective: To evaluate the survival, complications and prognostic factors in patients with stageⅠb2 Ⅱa2 cervical squamous cell carcinoma treated by primarily radical surgery or without postoperative adjuvant therapy. Methods: The clinical pathological data of Cancer Hospital University Chinese Academy Sciences from January 2015 to 2018 were retrospectively analyzed. All underwent Querleu-Morrow classification (Q-M classification) C2 surgery, including extensive hysterectomy+pelvic...