Abstract Variations in neural health along the cochlea can degrade spectral and temporal representation of sounds conveyed by cochlear implants (CIs). We evaluated compared one electrophysiological measure two behavioural measures that have been proposed as estimates patterns, order to explore extent which different provide converging consistent estimates. All were obtained from same 11 users Cochlear Corporation CI. The multipulse integration (MPI) polarity effect (PE), both measured on...

Objectives: Electrically evoked compound action-potentials (ECAPs) can be recorded using the electrodes in a cochlear implant (CI) and represent synchronous responses of electrically stimulated auditory nerve. ECAPs obtained forward-masking method that measures neural response to probe masker electrode separately combination. The panoramic ECAP (PECAP) analyses measured multiple combinations uses nonlinear optimization algorithm estimate current spread from each health along cochlea....

Hypothesis: Stimulation-Current-Induced Non-Stimulating Electrode Voltage Recordings (SCINSEVs) can help detect extracochlear electrodes for a variety of Cochlear Implant (CI) devices. Background: Extracochlear (EEs) occur in 9 to 13% cochlear implantations and commonly go unnoticed without imaging. Electrodes on the electrode array located extracochlearly are associated with non-auditory stimulation decrease speech outcomes. We have previously shown that SCINSEVs, hardware software from one...

Cochlear implants are a life-changing technology for those with severe sensorineural hearing loss, partially restoring through direct electrical stimulation of the auditory nerve. However, they known to elicit an immune response resulting in fibrotic tissue formation cochlea that is linked residual loss and suboptimal outcomes. Intracochlear fibrosis difficult track without postmortem histology, no specific marker exists. In this study, tissue-engineered model cochlear developed following...

Purpose: For some cochlear implants (CIs), it is possible to focus electrical stimulation by partially returning current from the active electrode adjacent, intra-cochlear electrodes (partial tripolar (pTP) stimulation). Another method achieves opposite: “blurring” stimulating multiple simultaneously. The Panoramic ECAP Method (PECAP) provides a platform investigate their effects in detail measuring Electrically-Evoked Compound Action-Potentials (ECAPs) and estimating spread neural...

For some cochlear implants (CIs), it is possible to focus electrical stimulation by partially returning current from the active electrode nearby, intra-cochlear electrodes (partial tripolar (pTP) stimulation). Another method achieves opposite: "blurring" stimulating multiple simultaneously. The Panoramic ECAP (PECAP) provides a platform investigate their effects in detail measuring electrically evoked compound action potentials and estimating spread neural responsiveness along length of CI...

Variations in neural health along the cochlea can degrade spectral and temporal representation of sounds conveyed by cochlear implants (CIs) . We evaluated compared several methods that have been proposed as estimates patterns, order to explore extent which different measures provide converging consistent estimates. All were obtained from same 11 users Cochlear Corporation CI. The two behavioural multipulse integration (MPI) polarity effect (PE), both measured on each seven electrodes per...

The knowledge of patient-specific neural excitation patterns from cochlear implants can provide important information for optimising efficacy and improving speech perception outcomes. Panoramic ECAP (or ‘PECAP’) method (Cosentino, et al., 2015) uses forward-masked electrically evoked compound action potentials (ECAPs) to estimate activation implant (CI) stimulation. algorithm requires ECAPs be measured loudness-balanced stimuli all combinations probe masker electrodes, takes advantage...

OBJECTIVES: Cochlear-implant companies manufacture devices with different electrode array types. Some arrays have a straight geometry designed for minimal neuronal trauma, while others are precurved and to position the electrodes closer cochlear neurons. Due their differing geometries, it’s possible that not only positioned differently inside cochlea, but also produce patterns of electrical spread excitation. The Panoramic ECAP method (PECAP) provides detailed estimates peripheral neural...

Finding objective measures of auditory perception when using cochlear implants (CIs) is important to provide clinical tools for diagnosis and device programming, as well scientific investigations into electrical hearing. Due the contamination electrophysiological recordings by CI stimulation artefacts, reciprocal constraints typically exist on type eliciting stimuli that can be used neural response measured, making it difficult disentangle effects stimulus properties. Here, we report three...

Purpose: Variations in neural survival along the cochlear implant electrode array leads to off-place listening, resulting poorer speech understanding outcomes for recipients. Therefore, it is important develop and compare clinically viable tests identify these patient-specific intra-cochlea differences. Methods: We derived health a group of experienced adult recipients using two methods: difference between psychophysical detection thresholds bipolar vs. monopolar mode Panoramic...

Objectives: Electrically-Evoked Compound Action-Potentials (ECAPs) can be recorded using the electrodes in a cochlear implant (CI) and represent synchronous responses of electrically-stimulated auditory-nerve. ECAPs obtained forward-masking method that measures neural response to probe masker electrode separately combination. The Panoramic ECAP (PECAP) multiple combinations uses nonlinear optimization algorithm estimate current spread from each health along cochlea. However, measurement is...