A5103268942- Nanoparticles: synthesis and applications
- Cancer Risks and Factors
- Monoclonal and Polyclonal Antibodies Research
- Enterobacteriaceae and Cronobacter Research
- Nanocomposite Films for Food Packaging
- Research on Leishmaniasis Studies
- Reproductive Biology and Fertility
- Phytochemical compounds biological activities
- Dielectric properties of ceramics
- Nanoparticle-Based Drug Delivery
- Insect and Pesticide Research
- Endodontics and Root Canal Treatments
- Cancer-related Molecular Pathways
- Fungal Infections and Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
Universidade de Brasília
2010-2021
This study reports on in vitro and vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising amphotericin B loaded onto surface pre-coated (with double-layer lauric acid) magnetite nanoparticles. The compared two drugs; i.e., this form free B. We found nanocomplex exhibited without cytotoxicity human urinary cells with low peritoneal macrophages. also evaluated efficacy experimental paracoccidioidomycosis. BALB/c mice were...
Metformin (dimethyl-biguanide) is an insulin-sensitizing agent that lowers fasting plasma-insulin concentration, wherefore it's wide use for patients with a variety of insulin-resistant and prediabetic states, including impaired glucose tolerance. During pregnancy it further resource reducing first-trimester loss in women the polycystic ovary syndrome. We tested metformin genotoxicity cells Chinese hamster ovary, CHO-K1 (chromosome aberrations; comet assays) mice (micronucleus assays)....
Background Photodynamic therapy (PDT) using chloroaluminium phthalocyanine (ClAlPc) and paromomycin sulfate (PM) can be effective against New World Leishmania species involved in cutaneous leishmaniasis (CL). The aim of this study is to assay the skin permeation antileishmanial effects a nanoemulsion (NE) containing both ClAlPc PM experimental CL by (Viannia) braziliensis. Material methods Cremophor ELP/castor oil-based NEs were prepared low-energy method characterized for their...
OBJECTIVE: Endodontic irrigants solutions with antibacterial activity Have Been used in treatment of teeth infected root canals; However, These Can irritate periapical tissues. The aim this study was to Evaluate the cytotoxity and genotoxicity different endodontic - sodium hypochlorite (1% 2%), calcium hydroxide (0.2%), HCT20 human KB cells. MATERIAL AND METHOD: Cells incubated Were is 2 24 hours. cell viability Assessed after trypan blue exclusion frequency death Mechanism (apoptotic or...