Ménière's disease is characterised by severe vertigo attacks and hearing loss. Intratympanic gentamicin, the standard treatment for refractory disease, reduces vertigo, but damages vestibular function can worsen hearing. We aimed to assess whether intratympanic administration of corticosteroid methylprednisolone compared with gentamicin.In this double-blind comparative effectiveness trial, patients aged 18-70 years unilateral were enrolled at Charing Cross Hospital (London, UK) Leicester...

Objective To measure the frequency dynamics of cervical and ocular vestibular evoked myogenic potentials in healthy subjects patients with Ménière’s disease. Study Design A prospective cohort study. Setting university teaching hospital. Subjects Eight volunteers (16 ears) 12 adult unilateral disease (8 definite 4 probable disease) by American Academy Otolaryngology – Head Neck Surgery diagnostic criteria. Interventions Cervical generated tone bursts at 250, 500, 750, 1,000, 1,500, 2,000,...

This study seeks to define the most appropriate guidelines for selection of patients magnetic resonance imaging (MRI) exclude a vestibular schwannoma. Improved may reduce patient anxiety and improve resource utilization. All MRIs internal auditory meatus, performed during year 2000, were reviewed. Audiograms symptoms collated all ’positive’ scans 100 negative scans. Information was analysed using seven published protocols other defined frequency specific criteria. A diagnosis schwannoma made...

Objective To identify distinct clinical subtypes of Ménière's disease by analyzing data acquired from a UK registry patients who have been diagnosed with disease. Study Design Observational study. Methods Patients were identified at secondary/tertiary care clinics. Cluster analysis was performed grouping participants sharing similar characteristics and risk factors into groups based on defined measure similarity. Results A total 411 recruited this Two main clusters identified: ear infections...

Congenital sinuses arising from the pyriform fossae are rare. They may present as neck cysts, recurrent abscesses, thyroiditis or neonatal stridor. Children typically undergo multiple surgical procedures before diagnosis is made. We our recent experience of five third-pouch and four fourth-pouch sinuses, including one bilateral case. The median age at presentation was years. mean number operations prior to six (range 0-13), with a delay made by barium swallow, ultrasound, pharyngoscopy open...

Abstract Objectives To explore the impact of COVID‐19 on management and outcomes acute paediatric mastoiditis across UK. Design National retrospective prospective audit. Setting 48 UK secondary care ENT departments. Participants Consecutive children aged 18 years or under, referred to with a clinical diagnosis mastoiditis. Main outcome measures Cases were divided into Period 1 (01/11/19‐15/03/20), before population instructed reduce social contact, 2 (16/03/20‐30/04/21), following this....

Abstract Objective/Hypothesis : The hypotheses of the study were that congenital hearing impairment in infants can result from isolated loss inner hair cells cochlea and this is shown by presence abnormal positive summating potentials on round window electrocochleography. objectives to establish proportion with affected, nature cochlear lesion, its etiology. And highlight important implications for otoacoustic emissions testing universal neonatal screening. Study Design A prospectively...

Introduction: The most common cause of barotitis is pressure changes induced during descent in aviation. incidence after air flight has been reported to vary from 8% 17%. Objectives: We conducted this study estimate the flight, evaluate whether can be reduced by nasal balloon inflation descent, and, finally, effect case negative middle ear landing. Study Design: Aircraft passengers were examined otoscopy and tympanometry before flying filled a questionnaire inquiring about problems. On half...

Hearing screening for newborn babies is an established protocol in many high-income countries. Implementing such has yielded significant socioeconomic advantages at both individual and societal level. This yet to permeate low/middle-income countries (LMIC). Here, we illustrate how hearing needs be contextually adapted effective utilisation implementation LMIC. Specifically, this advocates the use of auditory brainstem testing as first-line approach. We propose that adaptation serves maximise...

In this study, we examined whether vestibular migraine, as a source of increased perceptual uncertainty due to the associated dizziness, interferes with adaptive learning.

Ménière's disease is a disabling condition causing vertigo and hearing loss yet remains incompletely understood. Registry studies have the potential to answer important questions about phenotypes natural history of clinical conditions. The aim this study was explore feasibility patient-centered national registry. This an observational carried out at 4 state-funded hospitals independent clinics, within 3 distinct urban rural regions UK. Adults with were eligible participate. A range patient...

Community consultation is necessary to ensure the uptake and use of community-based screening intervention detect early childhood disabilities, as its absence can result in poor service acceptance usage. To document stakeholders' perspectives regarding planning a communication disorder (an impairment ability receive, send, process comprehend concepts or verbal, non-verbal graphic symbol systems) programmes for pre-schoolers.

Abstract Objective To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit. Methods A prospective study was conducted 40 consecutive referred our group age-matched controls were also included. All underwent real-time reverse transcriptase polymerase chain reaction testing for coronavirus-2. Symptoms fever, cough and anosmia noted group. Results The mean age 66.5 ± 22.4 years There 22 males...

Abstract Background Coronavirus disease 2019 and other factors have driven interest in conducting remote consultations, but there has been little research on this topic neuro-otology. With suitable preparation, neuro-otology patients with dizziness can assessments that include elements of neuro-otological physical examination, tailored management onward pathways arranged. Methods This paper reports experience consultation over 700 patient consultations suggests a systematic approach,...