- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Cerebral Venous Sinus Thrombosis
- Visual perception and processing mechanisms
- Migraine and Headache Studies
- Virtual Reality Applications and Impacts
- Transcranial Magnetic Stimulation Studies
- Multisensory perception and integration
- Hearing, Cochlea, Tinnitus, Genetics
- Spatial Neglect and Hemispheric Dysfunction
- Spatial Cognition and Navigation
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Facial Nerve Paralysis Treatment and Research
- EEG and Brain-Computer Interfaces
- Motor Control and Adaptation
- Balance, Gait, and Falls Prevention
- Neural dynamics and brain function
- Augmented Reality Applications
- Surgical Simulation and Training
- Optical measurement and interference techniques
- Cardiovascular Syncope and Autonomic Disorders
- Cerebrovascular and Carotid Artery Diseases
- Ocular Diseases and Behçet’s Syndrome
Johns Hopkins Medicine
2016-2025
Johns Hopkins University
2016-2025
Johns Hopkins Hospital
2014-2025
All India Institute of Medical Sciences
2021
World Health Organization
2021
NewYork–Presbyterian Hospital
2021
Institute of Liver and Biliary Sciences
2021
University of California, Berkeley
2020
Hebrew University of Jerusalem
2019
Neurology, Inc
2017
An intact cerebellum is a prerequisite for optimal ocular motor performance. The fine-tunes each of the subtypes eye movements so they work together to bring and maintain images objects interest on fovea. Here we review major aspects contribution control. approach will be based structural-functional correlation, combining effects lesions results from physiologic studies, with emphasis cerebellar regions known most closely related function: (1) flocculus/paraflocculus high-frequency (brief)...
This paper presents diagnostic criteria for vestibular migraine, jointly formulated by the Committee Classification of Vestibular Disorders Bárány Society and Migraine Subcommittee International Headache (IHS). It contains a literature update while original from 2012 were left unchanged. The classification defines migraine probable migraine. was included in appendix third edition (ICHD-3, 2013 2018) as first step new entities, accordance with usual IHS procedures. Probable may be later...
Although the pull of gravity, primarily detected by labyrinth, is fundamental input for our sense upright, vision and proprioception must also be integrated with vestibular information into a coherent perception spatial orientation. Here, we used transcranial magnetic stimulation (TMS) to probe role cortex at temporal parietal junction (TPJ) right cerebral hemisphere in upright. We measured perceived vertical orientation visual line; that is, subjective (SVV), after short period continuous...
The Segment Anything Model (SAM) is a new image segmentation tool trained with the largest available dataset. model has demonstrated that, prompts, it can create high-quality masks for general images. However, performance of on medical images requires further validation. To assist development, assessment, and application SAM images, we introduce Any Medical (SAMM), an extension 3D Slicer - processing visualization software extensively used by imaging community. This open-source to its...
The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, have found that SAM may limited performance images compared to state-of-the-art non-foundation models. Regardless, the community sees potential in extending, fine-tuning, modifying, and evaluating for analysis imaging. An increasing number works been published focusing mentioned four directions, where variants are proposed. To this...
Torsional eye movements are rotations of the around line sight. Measuring torsion is essential to understanding how brain controls position and it creates a veridical perception object orientation in three dimensions. Torsion also important for diagnosis many vestibular, neurological, ophthalmological disorders. Currently, there multiple devices methods that produce reliable measurements horizontal vertical movements. torsion, however, noninvasively reliably has been longstanding challenge,...
Patients with vestibular migraine (VM) often report dizziness changes in the head or body position. Such symptoms raise possibility of dysfunction neural mechanisms underlying spatial orientation these patients. Here we addressed this issue by investigating effects static tilt on errors perception upright a group 27 VM patients comparison healthy controls. Perception was measured dark room using subjective visual vertical (SVV) paradigm at three positions (upright, +/- 20º). were also...
Transcranial magnetic stimulation is a noninvasive medical procedure that can modulate brain activity, and it widely used in neuroscience, neurology research, clinical practice. Compared to manual operators, robots may improve the outcome due their superior accuracy repeatability. However, there has not been accepted standard protocol for performing robotic TMS using fine-segmented images, resulting arbitrary planned angles with respect true boundaries of modulated cortex. Given recent study...
Conclusion: vOCR can detect loss of otolith-ocular function without specifying the side vestibular loss. Since is measured with a simple head tilt maneuver, it be potentially used as bedside clinical test in combination video impulse test.Objective: Video-oculography (VOG) goggles are being integrated into assessment patients disorders. Lacking, however, method to evaluate otolith function. This study validated VOG for function.Methods: was measure ocular counter-roll (vOCR) 12 healthy...
Patients with acute vestibular disorders are often a diagnostic challenge for neurologists, especially when the evaluation must be conducted remotely. The clinical dilemma remains: Does patient have benign peripheral inner ear problem or worrisome central disorder, such as stroke? use of focused history and virtual HINTS (head impulse test, nystagmus evaluation, test skew) examination key steps towards correctly diagnosing triaging vertiginous patient. When looking signs vestibulo-ocular...
We maintain a stable perception of the visual world despite continuous movements our eyes, head and body. Perception upright is key aspect such orientation constancy. Here we investigated whether changes in during sustained tilt were related to simultaneous torsional position eyes. used subjective vertical (SVV) task, modified track over time, custom video method measure ocular torsion simultaneously. tested 12 subjects position, prolonged (~15 min) lateral tilts 20 degrees, also after...
Differentiating benign from dangerous causes of dizziness or vertigo presents a major diagnostic challenge for many clinicians. Bedside presentations peripheral vestibular disorders and posterior fossa strokes are often indistinguishable other than by few subtle eye movements. The most challenging these to interpret is the head impulse test (HIT) vestibulo-ocular reflex (VOR) function. There have been advances in portable video-oculography (VOG) quantification video HIT (vHIT), but...