Amlesh Seth

ORCID: 0000-0003-0387-3125
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About
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Research Areas
  • Bladder and Urothelial Cancer Treatments
  • Urological Disorders and Treatments
  • Renal cell carcinoma treatment
  • Urinary and Genital Oncology Studies
  • Kidney Stones and Urolithiasis Treatments
  • Prostate Cancer Treatment and Research
  • Pediatric Urology and Nephrology Studies
  • Renal and related cancers
  • Prostate Cancer Diagnosis and Treatment
  • Urologic and reproductive health conditions
  • Ureteral procedures and complications
  • Testicular diseases and treatments
  • Radiomics and Machine Learning in Medical Imaging
  • MRI in cancer diagnosis
  • Cancer Genomics and Diagnostics
  • Pelvic floor disorders treatments
  • Urinary Bladder and Prostate Research
  • Diverticular Disease and Complications
  • Genital Health and Disease
  • Sarcoma Diagnosis and Treatment
  • Medical Imaging and Pathology Studies
  • Hernia repair and management
  • Diagnosis and treatment of tuberculosis
  • Renal and Vascular Pathologies
  • Epigenetics and DNA Methylation

All India Institute of Medical Sciences
2016-2025

All India Institute of Medical Sciences Bhopal
2009-2024

All India Institute of Medical Sciences Raipur
2009-2024

National Institute of Medical Statistics
2024

Creative Commons
2023

Temple University Hospital
2021

All India Institute of Medical Sciences Rishikesh
2020

Christie's
2016

Voluntary Health Association Of India
2012

Gujarat Vidyapith
2010

No AccessJournal of UrologyAdult urology1 Mar 2007Laparoscopic Versus Open Radical Nephrectomy for Large Renal Tumors: A Long-Term Prospective Comparison A.K. Hemal, A. Kumar, R. P. Wadhwa, Seth, and N.P. Gupta HemalA.K. Hemal More articles by this author , KumarA. Kumar KumarR. WadhwaP. Wadhwa SethA. Seth GuptaN.P. View All Author Informationhttps://doi.org/10.1016/j.juro.2006.10.053AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...

10.1016/j.juro.2006.10.053 article EN The Journal of Urology 2007-02-11

OBJECTIVES To compare the safety and efficacy of two alternatives for surgically treating symptomatic benign prostatic hyperplasia (BPH), i.e. transurethral vapour resection prostate (TUVRP) holmium laser enucleation (HOLEP), with (TURP), standard surgical therapy, as large prostates is associated greater morbidity, to date there no simultaneous comparison these three methods. PATIENTS AND METHODS We prospectively randomized 150 patients (50 in each group) BPH glands >40 g undergo either...

10.1111/j.1464-410x.2006.05862.x article EN BJU International 2005-12-06

Rationale: Despite the success of several standards care treatment options in metastatic castration-resistant prostate cancer (mCRPC), a significant number patients attain therapeutic resistance and eventually develop disease progression. Managing these are currently challenging. Hence, there is an unmet need for further efficient that induce anti-tumor activity improve survival. The objective this study was to assess safety efficacy 225Ac-PSMA-617 targeted alpha therapy (TAT) mCRPC...

10.7150/thno.48107 article EN cc-by Theranostics 2020-01-01

Purpose The aim of this study was to evaluate the efficacy and safety 177 Lu-PSMA-617 radioligand therapy in metastatic castration-resistant prostate cancer (mCRPC). Methods In prospective, single-arm, single-institutional study, 90 mCRPC patients with progressive disease (PD) on second-line hormonal and/or docetaxel chemotherapy were recruited for study. All underwent diagnostic 68 Ga-PSMA-HBED-CC PET/CT, prior inclusion therapy. Included at 8- 12-weekly intervals. primary end point assess...

10.1097/rlu.0000000000002833 article EN Clinical Nuclear Medicine 2019-11-28

The purpose of the present paper was to study spectrum stone composition upper urinary tract calculi by X-ray diffraction crystallography technique, in patients managed at All India Institute Medical Sciences.Between 30 April 1998 and 31 March 2003, a total 1050 (900 renal, 150 ureteric) were analyzed. fragments collected after extracorporeal shock-wave lithotripsy, or retrieval endoscopic (percutaneous nephrolithotomy, ureterorenoscopy), laparoscopic various open surgical procedures....

10.1111/j.1442-2042.2004.00990.x article EN International Journal of Urology 2005-01-01

Background Though previous investigators have attempted to evaluate its utility in characterization of focal renal lesions, diffusion-weighted MR imaging (DW MRI) diseases is still an evolving field and role predicting the aggressiveness cell carcinoma (RCC) yet be established. Purpose To assess whether apparent diffusion coefficient (ADC) values can used determine nuclear grade histological subtype RCCs identify tumor attributes contributing variation ADC values. Material Methods The...

10.1258/ar.2011.110415 article EN Acta Radiologica 2012-04-01

Lu-DKFZ-PSMA-617, a urea-based compound, binds to the extracellular domain of prostate-specific membrane antigen, thus providing an effective target for treatment metastatic castration-resistant prostate cancer (mCRPC). Before its therapeutic use, it is necessary that radiation dosimetry this radiopharmaceutical be studied determine safe activity can administered in patients prevent haematological, renal and liver toxicity. The present study aimed assess pharmacokinetics Lu-DKFZ-PSMA-617...

10.1097/mnm.0000000000000606 article EN Nuclear Medicine Communications 2016-10-26

Recurrence of fistula is one the very common complications repair. The disease has immense psychosomatic effect on patients due to continuous leakage urine. Management recurrent vesico-vaginal (VVF) repair poses a challenge surgeons.Group I-12 with VVF, having robotic from August 2006 June 2008, were included in present study. Group II-20 matched all possible parameters VVF open surgical past taken as controls. Patients both groups evaluated by assessing relevant clinical details; performing...

10.1089/end.2010.0049 article EN Journal of Endourology 2010-08-02

Abstract Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current therapies for RCC patients are inefficient due lack diagnostic therapeutic markers. Our recent studies have suggested an association sperm-associated antigen 9 (SPAG9) with ovarian carcinomas. In present study, we investigated clinical relevance SPAG9 in patients. RT-PCR analysis showed expression transcript tissues lines. situ RNA hybridization immunohistochemistry analyses...

10.1158/0008-5472.can-08-1708 article EN Cancer Research 2008-10-15

We carried out this study to compare Glu-NH-CO-NH-Lys-(Ahx) [Ga(HBED-CC)] [Ga prostate-specific membrane antigen-11 (PSMA-11)] PET with multiparametric MRI (mpMRI) for the staging of high-risk prostate cancer.This was a prospective in which 36 patients cancer were included. The criteria inclusion biopsy-proven serum specific antigen at least 20 and/or Gleason's score 8. Each patient then underwent both gallium-68 (Ga)-PSMA PET/computed tomography (CT) and mpMRI including diffusion-weighted...

10.1097/mnm.0000000000000749 article EN Nuclear Medicine Communications 2017-09-29

To identify perioperative risk factors for postoperative systemic inflammatory response syndrome (SIRS) and suggest possible modifications to reduce morbidity.We prospectively analysed data such as history of pervious stone surgery, number configuration stones, presence stent or nephrostomy, any previous positive urine culture, intraoperative renal pelvic aspiration turbid on initial puncture, tracts required clearance operative time hypotension tachycardia all patients who underwent...

10.1159/000441954 article EN Urologia Internationalis 2016-01-01

Urine cytology is a highly specific modality for diagnosing high-grade urothelial carcinoma (HGUC), but plagued by low sensitivity and wide inter-observer variability mainly ascribed to the lack of an established template reporting. The Paris System (TPS) working group proposed such at 2013 International Congress Cytology, replete with objective criteria categorising specimens into one seven categories: non-diagnostic, negative HGUC, atypical cells, suspicious low-grade neoplasm others...

10.1111/cyt.12448 article EN Cytopathology 2017-08-22
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