A5100328670- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Mechanisms and Therapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Nerve injury and regeneration
- Pediatric health and respiratory diseases
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Asthma and respiratory diseases
- Lung Cancer Research Studies
- Lymphoma Diagnosis and Treatment
- Liver Disease and Transplantation
- Sinusitis and nasal conditions
- Scoliosis diagnosis and treatment
- Vascular Tumors and Angiosarcomas
- Nasal Surgery and Airway Studies
- Neurological and metabolic disorders
- Head and Neck Surgical Oncology
- Esophageal Cancer Research and Treatment
- Hereditary Neurological Disorders
- Cancer Immunotherapy and Biomarkers
- Orthopedic Surgery and Rehabilitation
Guangxi Medical University
2018-2025
University of South China
2017-2023
China Medical University
2005-2023
Chenzhou First People's Hospital
2017-2023
Xiangnan University
2023
Yueyang Hospital
2023
Shanghai University of Traditional Chinese Medicine
2023
Guangxi University of Chinese Medicine
2023
University of Macau
2022
Hunan Provincial People's Hospital
2019
A double-blinded study was conducted to evaluate the dose response of hemiparkinsonian rhesus monkeys intracerebroventricular (ICV) injections recombinant methionine human glial cell line-derived neurotrophic factor (GDNF). Thirty with stable features were divided into six treatment groups (vehicle, 10, 30, 100, 300 and 1000 microg GDNF; n = 5/group). Each animal received 4 ICV administrations spaced at four week intervals. In addition, animals followed for mo after last injection....
More effective treatment strategies need to be established for patients with Barcelona Clinic Liver Cancer (BCLC)-B stage hepatocellular carcinoma (HCC). The combination of transarterial chemoembolization (TACE) lenvatinib and immune checkpoint inhibitors (ICIs) has been shown have potential in the unresectable HCC. However, real-world data on use this combined therapy BCLC-B HCC are limited. Therefore, study aimed validate efficacy safety TACE plus ICIs a setting. A total 121 who were newly...
The aim of this study was to compare the treatment response, survival, liver function, and adverse event incidence drug-eluting bead transcatheter arterial chemoembolization using CalliSpheres microspheres with conventional in patients hepatocellular carcinoma. Seventy-three carcinoma who received (using microspheres) or were consecutively enrolled. Treatment response assessed by modified Response Evaluation Criteria Solid Tumors at month 1/month 3/month 6; posttreatment, function indexes,...
Historically, the incidence of malaria in Hainan Province, China has been high. However, since 2001 decreased due to large-scale, public educational, promotional campaigns and adoption preventative measures against following fast growth socio-economic development. The present study analysed correlation between prevention social economic development on from 2013.The data were collected various cities counties Province 2013 by grey analysis system.Seasonal preventive medication local fiscal...
Prospective study of the sagittal spino-pelvic parameters and deformity in low-grade isthmic spondylolisthesis preoperation postoperation.To better understand how surgery influences alignment spondylolisthesis.Over past decade, importance was recognized. However, postoperative change balance still unclear.Forty-nine patients (mean age, 53.2±7.2 y) with L5-S1 60 normal volunteers 44.5±8.4 were included study. Each subject had a radiograph that allowed measurement before after surgery. The...
The potential of dopaminergic treatments to improve upper limb motor movements was tested in 7 aged rhesus monkeys using L-3,4-dihydroxyphenylalanine (L-dopa) or the selective dopamine uptake inhibitor 1-2(bis[4-fluorophenyl] methoxy]ethyl)-4-(3-phenylpropyl) piperazine hydrochloride (GBR-12909). Six young were studied for comparison. L-Dopa GBR-12909 improved performance by up 40% animals. At this point their comparable that adults. Dopaminergic therapy could be useful elderly humans...
To determine the standard remnant liver volume (SRLV) threshold to avoid postoperative hepatic insufficiency inpatients in different stages of fibrosis who undergo right hemi-hepatectomy.Data for 85 patients at our single medical center were analysed prospectively examine whether following factors differed significantly between those experienced and did not: height, prothrombin time, volume, SRLV or stage.Logistic regression showed stage be independent risk insufficiency. The predicting was...
To explore the most appropriate treatment for patients with hepatocellular cancer (HCC)>10 cm by using Barcelona Clinic Liver Cancer (BCLC) classification.A total of 124 HCC undergoing surgery were selected. Disease-free survival (DFS), overall (OS) and prognostic factors respectively assessed.This study showed that cumulative 1-, 3-, 5-year rates 79.7%, 59.8% 41.6% in BCLC-A patients, 76.2%, 9.5% 0% BCLC-B 44.9%, BCLC-C respectively. The DFS 49%, 24.5% 9.1% 7.5%, No survived 1 year after...
Primary diffuse large B-cell tumor of the uterus is a rare clinical condition with similar presentation to gynecologic tumors and easily misdiagnosed. We report case postmenopausal woman who presented pelvic mass. Her ultrasound MRI examinations suggested enlargement uterus, leading us consider diagnosis lymphoma. The histological examination uterine mass confirmed patient received 6 cycles chemotherapy R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine prednisone) 2 consolidation...
Using in vivo multiphoton fluorescent dosimetry, we demonstrate that the clearance dynamics of Indocyanine Green (ICG) blood can quickly reveal liver function reserve. In normal rats, ICG retention rate was below 10% at 15-minute post-administration; While rat with severe hepatocellular carcinoma (HCC), is over 40% due to poor metabolism. With a 785 nm CW laser, fluorescence dosimeter evaluate reserve 1/10 clinical dosage without any sampling. future, this low-dosage dosimetry be applied for...
There have been three major global outbreaks of acute respiratory disease caused by coronavirus in the last two decades. The ongoing Coronavirus Disease 2019 (COVID-19) first emerged Wuhan, China, is most dangerous, which spread to 163 countries and 6 continents a public health emergency worldwide. outbreak Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) originated from bats, spreads rapidly human human. As 17 March 2020, there 179,112 confirmed cases 7426 deaths worldwide, with mortality...
At present, there are still disputes on the treatment of surgery for patients with stage B hepatocellular carcinoma (HCC). This study sought to investigate whether up-to-7 criterion could be used decide HCC in Barcelona Clinic Liver Cancer (BCLC-B).We analyzed 340 BCLC-B who treated hepatectomy or transcatheter arterial chemoembolization (TACE). Of 285 underwent hepatectomy, 108 met and 177 exceeded it. All 55 TACE group criterion. We obtained tumor status through inpatient medical records,...
4111 Background: uHCC still lacks effective treatments, combination of antiangiogenic targeted drugs and immune checkpoint inhibitors showed promising efficacy. TACE induces tumor necrosis antigen release, may synergize with immunotherapy. This study was to evaluate the efficacy safety in TIS LEN patients uHCC. Methods: a single-center, single-arm, open-label phase II exploratory clinical (NCT05131698). Eligible were BCLC C stage not candidates for surgical resection or liver...
Effective treatment for patients with advanced unresectable hepatocellular carcinoma (HCC) is severely lacking. The most common clinical treatments include a combination of immunotherapy, molecular targeted agents, and transarterial chemoembolization (TACE). combinations therapies likely to lead complete recovery are unclear. cases in this study were treated TACE therapy radiofrequency ablation followed by massive tumor antigen release as way enhance the effect immune therapy, programmed...
To study factors affecting the liver regeneration after hepatectomy.With 3D reconstitution technology, ability of 117 patients was analysed, and relative were studied.There no statistically difference between volume simulated resection actual resection. All livers had different degrees surgery. Age, gender blood indicators impact on regeneration, while surgery time, intraoperative loss, flow blocking time ways a significant regeneration; In addition, patients' own pathological status,...
Primary hepatic non-Hodgkin's lymphoma (NHL) is an extremely rare disease that commonly neglected as a possible diagnosis. The present study reports the case of middle-aged male with chronic hepatitis B in which primary NHL and rectal cancer occurred simultaneously. A large solitary tumor left lobe liver was incidentally detected on routine examination prior to laparoscopic resection cancer. Laparoscopic biopsy were performed pathology revealed adenocarcinoma. Systemic staging no evidence...