A5003104874- Heart Rate Variability and Autonomic Control
- Spatial Neglect and Hemispheric Dysfunction
- EEG and Brain-Computer Interfaces
- Vagus Nerve Stimulation Research
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Stress Responses and Cortisol
- Hemispheric Asymmetry in Neuroscience
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Physiological and biochemical adaptations
- Neurobiology and Insect Physiology Research
- Dementia and Cognitive Impairment Research
- Musculoskeletal pain and rehabilitation
- Diet and metabolism studies
- Cell Image Analysis Techniques
- Autism Spectrum Disorder Research
- Motor Control and Adaptation
- Advanced Memory and Neural Computing
- Cerebrovascular and Carotid Artery Diseases
- AI in cancer detection
- Animal Behavior and Reproduction
- Health, Environment, Cognitive Aging
University of Florida
2015-2024
Malcom Randall VA Medical Center
2015-2024
Gainesville Obstetrics & Gynecology
2024
Wan Fang Hospital
2024
The Robertson Trust
2024
Milton J. Rubenstein Museum of Science and Technology
2024
North Florida/South Georgia Veterans Health System
2017-2024
University of Florida Health
2017-2021
Cognitive Research (United States)
2017-2021
Allen Institute for Brain Science
2021
Few studies have examined whether familiarity of partner affects social responses in children with autism. This study investigated heart rate regulation (respiratory sinus arrhythmia [RSA]: The myelinated vagus nerve's rate) and temporal-parietal electroencephalogram (EEG) activity while nineteen 8- to 12-year-old autism 14 controls viewed videos a familiar an unfamiliar person reading story. Children had lower overall RSA levels exhibited decreased the person, versus control children. Both...
A core manifestation of post-traumatic stress disorder (PTSD) is a disconnection between physiological state and psychological or behavioral processes necessary to adequately respond environmental demands. Patients with PTSD experience abnormal oscillations in autonomic states supporting either fight flight behaviors withdrawal, immobilization, dissociation without an intervening "calm" that would provide opportunities for positive social interactions. This defensive disposition adaptive...
Posttraumatic stress disorder (PTSD) is a reaction to trauma that results in chronic perception of threat, precipitating mobilization the autonomic nervous system, and may be reflected by disinhibition limbic structures. A common injury preceding PTSD veterans mild traumatic brain (mTBI). This due vulnerability white matter these networks such damage affect treatment response. We evaluated transcutaneous vagal nerve stimulation (tVNS), non-invasive, low-risk approach alter functions...
Extracellular free water within cerebral white matter tissue has been shown to increase with age and pathology, yet the cognitive consequences of in typical aging prior development neurodegenerative disease remains unclear. Understanding contribution function older adults may provide important insight into neural mechanisms process. A diffusion-weighted MRI measure extracellular as well a commonly used diffusion metric (fractional anisotropy) along nine bilateral pathways were examined for...
Sleep problems are common among veterans with post-traumatic stress disorder and closely associated hyperarousal symptoms. Transcutaneous vagus nerve stimulation (tVNS) may have potential to improve sleep quality in PTSD through effects on brain systems relevant sleep-wake regulation. The current pilot study examines the effect of 1 h tVNS administered at "lights out" architecture, microstructure, autonomic activity. Thirteen completed two nights laboratory-based polysomnography during which...
Neurons can have widely differing intrinsic membrane properties, in particular the density of specific conductances, but how these contribute to characteristic neuronal activity or pattern formation is not well understood. To explore relationship between and they influence motor neurons characterized leech heartbeat system, we developed a new multi-compartmental Hodgkin-Huxley style heart neuron model. do so, evolved population model instances, which differed capable achieving output targets...
There is growing concern about the health impact of heavy alcohol use in people infected with human immunodeficiency virus (HIV+). Mixed findings past studies regarding cognitive HIV+ adults have been mixed, inconsistent evidence that consumption exacerbates HIV-associated brain dysfunction. This study examined contributions current drinking, lifetime disorder (AUD), and age to deficits adults, relative other clinical factors. Cognitive performance (n = 104) was assessed, comparisons were...
Objective: Identification of biomarkers cognitive recovery after traumatic brain injury (TBI) will inform care and improve outcomes. This study assessed the utility neurofilament (NF-L pNF-H), a marker neuronal injury, informing performance following moderate-to-severe TBI (msTBI). Setting: Level 1 trauma center outpatient via postdischarge follow-up. Participants: N = 94. Inclusion criteria : Glasgow Coma Scale score less than 13 or 13-15 with clinical evidence on imaging. Exclusion...
NestMC is a new multicompartment neural network simulator currently under development as collaboration between the Simulation Lab Neuroscience at Forschungszentrum Jülich, Barcelona Supercomputing Center and Swiss National Center.NestMC will enable scales classes of morphologically detailed neuronal simulations on current future supercomputing architectures.A number "many-core" architectures such GPU Intel Xeon Phi based systems are available.To optimally use these emerging architecture...
Proton magnetic resonance spectroscopy (1H-MRS) is a noninvasive imaging technique that measures the concentration of metabolites in defined areas human brain vivo. The underlying structure natural metabolism-emotion relationships unknown. Further, there wide range between-person differences metabolite healthy individuals, but significance this variation for understanding emotion humans unclear. Here we investigated relationship two emotional constructs, agency and flexibility, with...
White matter changes are one potential etiology of behavioral in cerebrovascular disease. Whole brain diffusion tensor imaging–fractional anisotropy (DTI-FA) as a measure apparent white integrity is related to cognitive function However, not uniform, nor their effects. We examine the relationship between regional differences DTI-FA and cognition mood an ischemic-stroke sample. Participants were 108 patients, 3–6 months post stroke. Working memory, basic attention, recall, language,...
In the study of neural circuits underlying behavior and autonomic functions, stereotyped accessible nervous system medicinal leeches, Hirudo sp., has been particularly informative. These leeches express well-defined behaviors movements which are amenable to investigation at circuit neuronal levels. this review, we discuss some best understood these underlie them, focusing on swimming, crawling heartbeat. We also rudiments decision-making: selection between generally mutually exclusive level.