A5068080913- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Neural and Behavioral Psychology Studies
- EEG and Brain-Computer Interfaces
- Dementia and Cognitive Impairment Research
- Advanced Neuroimaging Techniques and Applications
- Heart Rate Variability and Autonomic Control
- HIV Research and Treatment
- Vagus Nerve Stimulation Research
- HIV/AIDS Research and Interventions
- Memory and Neural Mechanisms
- Neuroendocrine regulation and behavior
- HIV-related health complications and treatments
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
- Stress Responses and Cortisol
- Optical Imaging and Spectroscopy Techniques
- Diet and metabolism studies
- Transcranial Magnetic Stimulation Studies
- Tryptophan and brain disorders
- Metabolomics and Mass Spectrometry Studies
- Cannabis and Cannabinoid Research
- Sleep and related disorders
- Evolutionary Psychology and Human Behavior
- Spatial Neglect and Hemispheric Dysfunction
University of Florida Health
2017-2025
University of Florida
2016-2025
Malcom Randall VA Medical Center
2015-2023
Cognitive Research (United States)
2017-2023
New York Academy of Sciences
2023
John Wiley & Sons (Germany)
2023
Moss Landing Marine Laboratories
2023
Hudson Institute
2023
Florida College
2017-2022
McKnight Brain Research Foundation
2020-2022
The hippocampus is one of the most well studied structures in human brain. While age-related decline hippocampal volume documented, our knowledge about structure-function relationships was discovered context neurological and neurodegenerative diseases. relationship between cognitive aging structure absence disease remains relatively understudied. Furthermore, few studies that have investigated role produced contradictory results. To address these issues, we assessed 93 older adults from...
AbstractRecent research indicates that the neuropeptide oxytocin and gene for receptor (OXTR) have been implicated in modulation of various social behaviors, including those related to empathy sensitivity others. In this study, we examine hypothesis genetic variation OXTR is associated with autonomic reactions when perceiving others distress. We also explore possibility individual disposition empathic concern would differ by genotype. To address these questions, 51 male participants (18–35...
Working memory is an executive process that allows transitional information to be held and manipulated temporarily in stores before being forgotten or encoded into long-term memory. necessary for everyday decision-making problem solving, making it a fundamental the daily lives of older adults. relies heavily on frontal lobe structures known decline with age. The current study aimed determine neural correlates decreased working performance lobes by comparing cortical thickness surface area...
A core manifestation of post-traumatic stress disorder (PTSD) is a disconnection between physiological state and psychological or behavioral processes necessary to adequately respond environmental demands. Patients with PTSD experience abnormal oscillations in autonomic states supporting either fight flight behaviors withdrawal, immobilization, dissociation without an intervening "calm" that would provide opportunities for positive social interactions. This defensive disposition adaptive...
Introduction Walking in the home and community often involves performance of complex walking tasks. Understanding control such tasks is crucial to preserving independence quality life older adults. However, very little research has been conducted this area. Here we assess extent which two measures central nervous system (CNS) activity are responsive challenges posed by preparation Prefrontal cortical was measured functional near infrared spectroscopy (fNIRS) sympathetic arousal skin...
Background The acute consumption of excessive quantities alcohol causes well‐recognized neurophysiological and cognitive alterations. As people reach advanced age, they are more prone to decline. To date, the interaction current heavy (ethanol [ EtOH ]) aging remains unclear. This study tested hypothesis that negative consequences on neurocognitive function worse with age. Further, we evaluated relations between lifetime history dependence Methods Sixty‐six participants underwent a...
Posttraumatic stress disorder (PTSD) is a reaction to trauma that results in chronic perception of threat, precipitating mobilization the autonomic nervous system, and may be reflected by disinhibition limbic structures. A common injury preceding PTSD veterans mild traumatic brain (mTBI). This due vulnerability white matter these networks such damage affect treatment response. We evaluated transcutaneous vagal nerve stimulation (tVNS), non-invasive, low-risk approach alter functions...
Abstract Chronic pain is associated with brain atrophy limited evidence on its impact in the older adult's brain. We aimed to determine associations between chronic and a aging biomarker persons aged 60 83 years old. Participants of Neuromodulatory Examination Pain Mobility Across Lifespan (NEPAL) study (N = 47) completed demographic, psychological, assessments followed by quantitative sensory testing battery T1-weighted magnetic resonance imaging. estimated brain-predicted age difference...
Working memory, a fundamental short-term cognitive process, is known to decline with advanced age even in healthy older adults. Normal age-related declines working memory can cause loss of independence and decreased quality life. Cognitive training has shown some potential at enhancing certain processes, although, enhancements are variable. Transcranial direct current stimulation (tDCS), form non-invasive brain stimulation, promise abilities, may further the benefits from interventions....
Aging is associated with disruptions in the resting-state functional architecture of brain. Previous studies have primarily focused on age-related declines default mode network (DMN) and its implications Alzheimer's disease. However, due to mixed findings, it unclear if changes connectivity are linked cognitive decline healthy older adults. In present study, we evaluated influence intra-network coherence for four higher-order networks a sensitive measure aging (i.e., NIH Toolbox Fluid...
Atypical amygdala function and connectivity have reliably been associated with psychopathy. However, the is not a unitary structure. To examine how psychopathic traits in nonforensic sample are linked to response violence, this study used probabilistic tractography classify subnuclei based on anatomical projections from group of 43 male participants. The segmentation identified basolateral complex (BLA; lateral, basal, accessory basal subnuclei) central subnucleus (CE), which were as seeds...
Working memory is an executive process essential for everyday decision-making and problem solving that declines with advanced age. Transcranial direct current stimulation (tDCS) a non-invasive form of brain has demonstrated potential improving working performance in older adults. However, the neural mechanisms underlying effects tDCS on are not well understood. This mechanistic study investigated acute after-effects bilateral frontal (F3/F4) at 2 mA 12-min functional connectivity network We...
Heating of gradient coils and passive shim components is a common cause instability in the B0 field, especially when intensive sequences are used. The aim study was to set benchmark for typical drift encountered during MR spectroscopy (MRS) assess need real-time field-frequency locking on MRI scanners by comparing field data from large number sites. A standardized protocol developed 80 participating sites using 99 3T 3 major vendors. Phantom water signals were acquired before after an EPI...