- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Bipolar Disorder and Treatment
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury Research
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Posttraumatic Stress Disorder Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Personality Disorders and Psychopathology
- Sleep and Wakefulness Research
- Diet and metabolism studies
- Sleep and related disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Attention Deficit Hyperactivity Disorder
- Schizophrenia research and treatment
- Stress Responses and Cortisol
- Child and Adolescent Psychosocial and Emotional Development
- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Dementia and Cognitive Impairment Research
- Treatment of Major Depression
- Biochemical Analysis and Sensing Techniques
- Obsessive-Compulsive Spectrum Disorders
- Suicide and Self-Harm Studies
Ewha Womans University
2016-2025
University of Utah
2010-2023
Huntsman Cancer Institute
2023
Allen Institute for Brain Science
2013-2021
Dongwha Pharm (South Korea)
2013-2021
Korea Institute of Brain Science
2015-2017
Seoul National University Hospital
2004-2013
Seoul National University
2004-2013
Seattle University
2012
Ewha Womans University Medical Center
2012
Abstract The objective of this study was to evaluate the relationship between attention deficit‐hyperactivity/impulsivity symptoms and Internet addiction. In total, 535 elementary school students (264 boys, 271 girls; mean age, 11.0 ± 1.0 years) were recruited. presence or severity addiction assessed by Young's Addiction test. Parents teachers children completed DuPaul's deficit hyperactivity disorder (ADHD) rating scale (ARS; Korean version, K‐ARS) Child Behavior Checklists. Children with...
Bipolar disorder (BD) has substantial morbidity and incompletely understood neurobiological underpinnings.To investigate brain chemistry in medication-free individuals with BD.Two-dimensional proton echo-planar spectroscopic imaging (PEPSI) (32 x 32, 1-cm(3) voxel matrix) acquired axially through the cingulate gyrus was used to quantify regional chemistry.The Center for Anxiety Depression at University of Washington Seattle Research Programs McLean Hospital Massachusetts General...
<i>Background:</i> The aim of the study was to evaluate relationship between depression and Internet addiction among adolescents. <i>Sampling Method:</i> A total 452 Korean adolescents were studied. First, they evaluated for their severity with consideration behavioral characteristics primary purpose computer use. Second, we investigated correlations depression, alcohol dependence obsessive-compulsive symptoms. Third, biogenetic temperament as assessed by Temperament...
The effects of type 1 diabetes and key metabolic variables on brain structure are not well understood. Sensitive methods assessing structure, such as voxel-based morphometry (VBM), have previously been used to investigate central nervous system changes in a diabetic population. Using VBM, we compared patients aged 25–40 years with disease duration 15–25 minimal complications an age-matched, nondiabetic control group. We investigated whether lower than expected gray matter densities were...
Objective: This study was conducted to explore differences in cortical thickness between subjects with bipolar disorder and healthy comparison using surface‐based analysis. Methods: Brain magnetic resonance images were acquired from 25 21 subjects. Cortical analysis the Freesurfer application. Group thickness, defined by distance gray/white boundary pial surface, assessed statistical difference maps. Results: Subjects exhibited significantly decreased left cingulate cortex, middle frontal...
Excessive internet video game play (EIGP) has emerged as a leading cause of behavioral and developmental problems in adolescents. Recent research implicated the role striatal dopaminergic system maladaptations associated with EIGP. This study investigates reward-dependence characteristics EIGP adolescents it potentially relates to genetic polymorphisms temperament. Seventy-nine male 75 age- gender-matched healthy comparison were recruited. Associations tested respect (RD) scale Cloninger's...
<h3>Context</h3> A multiwave longitudinal neuroimaging study in a cohort of direct survivors South Korean subway disaster, most whom recovered from posttraumatic stress disorder 5 years after trauma, provided unique opportunity to investigate the brain correlates recovery severe psychological trauma. <h3>Objectives</h3> To region-specific mobilization during successful by assessing cortical thickness multiple times early trauma recovery, and examine whether brain-derived neurotrophic factor...
Antidepressants often take several weeks to work, but depressed women who took the antidepressant escitalopram plus 5 g/day of creatine monohydrate, a supplement that increases cellular energy, had earlier and greater symptom decreases than placebo. The authors found difference by second week treatment, remission rate at 8 was twice as high for group (52%) placebo (26%). Most side effects were attributed escitalopram, not creatine, serum creatinine elevated in treatment group.
Disease susceptibility and drug response of individuals are presumed to be different depending on their personality traits. The Sasang typology, a traditional Korean medical explains the individual differences vulnerability pathology proposes guidelines for safe effective use herbs traits.The purpose present study was evaluate psychologic physical characteristics types from perspective theory.After determining type 79 college students based Questionnaire Constitution Classification, traits...
Authors explored grey-matter density in 29 methamphetamine abusers and 20 healthy comparison subjects using voxel-based morphometry. Grey-matter changes performances on the Wisconsin Card Sorting test (WCST) were also compared between 11 short-term (<6 months) 18 long-term (⩾6 abstinent abusers. Methamphetamine had lower right middle frontal cortex (corrected p<0.05) more total errors WCST (p<0.01) relative to subjects. decrease correlated with (r=−0.45). Long-term significantly less than...
Abstract The authors evaluated the trait/state issues of harm avoidance in depressive‐spectrum disorders and its predictive potential for antidepressant response. Subjects with Diagnostic Statistical Manual Mental Disorders (4th edn; DSM‐IV) major depressive disorder ( n = 39), dysthymic 37), personality healthy control subjects 40) were Temperament Character Inventory 17‐item Hamilton Depression Rating Scale (HDRS‐17) at baseline after a 12 week treatment period. Higher scores predicted...