A5021124424- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Tryptophan and brain disorders
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Neural dynamics and brain function
- Mental Health Research Topics
- Treatment of Major Depression
- Child and Adolescent Psychosocial and Emotional Development
- Pain Mechanisms and Treatments
- Stress Responses and Cortisol
- Obsessive-Compulsive Spectrum Disorders
- Attention Deficit Hyperactivity Disorder
- Neuroscience and Music Perception
- GABA and Rice Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Parkinson's Disease Mechanisms and Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Advanced NMR Techniques and Applications
- Pain Management and Placebo Effect
- Psychosomatic Disorders and Their Treatments
Instituto Nacional de Neurología y Neurocirugía
2015-2024
KU Leuven
2021
University of Calgary
2021
Churchill Hospital
2021
University of Oxford
2021
Douglas Mental Health University Institute
2021
Stanford University
2021
Taipei Medical University-Shuang Ho Hospital
2021
Universidad de Antioquia
2021
Instituto Nacional de Cancerología
2015
Increased glutamate levels in the right associative striatum have been described patients during a first episode of psychosis. Whether this increase would persist after effective antipsychotic treatment is unknown.To compare antipsychotic-naive with first-episode psychosis and cerebellar cortex using proton magnetic resonance spectroscopy before 4 weeks to these results normative data from sex-matched healthy control subjects.Before-after trial an inpatient psychiatric research unit among 24...
Glial disturbances are highly implicated in the pathophysiology of schizophrenia and may be linked with glutamatergic dysregulation. Myo-inositol (mI), a putative marker glial cells, choline (Cho), representative membrane turnover, both present larger concentrations within cells than neurons, their elevation is often interpreted to reflect activation. Proton magnetic resonance spectroscopy ( 1 H-MRS) allows for evaluation mI, Cho, glutamate, glutamate + glutamine (Glx), N -acetylaspartate...
Increased glutamate levels in the associative-striatum have been described subjects at ultra-high risk for psychosis (UHR); nevertheless, it is unclear whether this abnormality predicts conversion to psychosis. Nineteen UHR and 26 controls were studied using proton magnetic resonance spectroscopy. Subjects clinically followed 2 yr. Seven (37%) transitioned a psychotic disorder remaining 12 did not exhibit symptoms most recent follow-up. The transition group had higher compared both...
Background:Dysregulations of the major inhibitory and excitatory amino neurotransmitter systems γ-aminobutyric acid glutamate, respectively, have been described in patients with schizophrenia. However, it is unclear whether these abnormalities are present subjects at ultra-high risk for psychosis.
Heating of gradient coils and passive shim components is a common cause instability in the B0 field, especially when intensive sequences are used. The aim study was to set benchmark for typical drift encountered during MR spectroscopy (MRS) assess need real-time field-frequency locking on MRI scanners by comparing field data from large number sites. A standardized protocol developed 80 participating sites using 99 3T 3 major vendors. Phantom water signals were acquired before after an EPI...
Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical CHR-P state is largely undetermined. We aimed to quantify structural magnetic resonance imaging measures cortical surface area (SA), thickness (CT), subcortical volume (SV), intracranial (ICV) individuals compared with healthy controls (HC), relation subsequent transition a first episode psychosis. The ENIGMA consortium applied...
Abstract Background Cognition heavily relies on social determinants and genetic background. Latin America comprises approximately 8% of the global population faces unique challenges, many derived from specific demographic socioeconomic variables, such as violence inequality. While factors have been described to influence mental health outcomes, no large-scale studies with American carried out. Therefore, we aim describe cognitive performance a representative sample individuals schizophrenia...
Abstract Considerable evidence suggests that violent behavior observed in schizophrenic patients is motivated by psychotic symptomatology. The understanding of violence requires consideration psychiatric Objective: This study investigated the relationship between and symptomatology patients. Method: One hundred thirteen were recruited. Thirteen excluded due to concomitant substance abuse six months prior assessment. Diagnoses based on SCID‐I. Psychotic symptom severity was assessed with...