- Radiopharmaceutical Chemistry and Applications
- Various Chemistry Research Topics
- Cardiovascular and Diving-Related Complications
- Cancer, Hypoxia, and Metabolism
- Chemical Synthesis and Reactions
- Analytical Chemistry and Chromatography
- Lung Cancer Treatments and Mutations
- Congenital Heart Disease Studies
- Lymphoma Diagnosis and Treatment
- Bone health and treatments
- Liver Disease Diagnosis and Treatment
- Color perception and design
- Sulfur-Based Synthesis Techniques
- Takotsubo Cardiomyopathy and Associated Phenomena
- Synthesis and Biological Evaluation
- Heme Oxygenase-1 and Carbon Monoxide
- Liver physiology and pathology
- Nonlinear Optical Materials Research
- Trace Elements in Health
- Organoselenium and organotellurium chemistry
- PI3K/AKT/mTOR signaling in cancer
- Hepatitis B Virus Studies
- Surfactants and Colloidal Systems
- Chemical and Physical Properties in Aqueous Solutions
- Advanced Chemical Sensor Technologies
Tongji University
2014-2024
Beijing Hua Xin Hospital
2014
Qingdao University
2014
Affiliated Hospital of Qingdao University
2014
Anhui Medical University
2010
Central South University
2007-2010
Anhui Provincial Hospital
2010
Stony Brook University
2009
Northport VA Medical Center
2009
Peng Huanwu Center for Fundamental Theory
2006
Phosphoinositide 3-kinase (PI3K) p110alpha plays a key role in insulin action and tumorigenesis. Myocyte contraction is initiated by an inward Ca(2+) current (I(Ca,L)) through the voltage-dependent L-type channel (LTCC). The aim of this study was to evaluate whether also controls cardiac contractility regulating LTCC.Genetic ablation (also known as Pik3ca), but not p110beta Pik3cb), myocytes adult mice reduced I(Ca,L) blocked signaling heart. p110alpha-null had number LTCCs on cell surface...
Contraction of cardiac myocytes is initiated by Ca(2+) entry through the voltage-dependent L-type channel (LTCC). Previous studies have shown that phosphatidylinositol (PI) 3-kinase signaling modulates LTCC function. Because PI 3-kinases are key mediators insulin action, we investigated whether function affected in diabetic animals due to reduced signaling.We used whole-cell patch clamping and biochemical assays compare insulin-deficient mice heterozygous for Ins2(Akita) mutation versus...
Smartphone thermal cameras can be used to observe heat transfer or patterns in crystallization, evaporation, mixing of liquids, and chemical reactions. The experiments described this paper demonstrate that IR imaging provide students with rich learning exploring opportunities would otherwise infeasible too time-consuming. precision sensitivity smartphone are sufficient for use chemistry education. A accessory is worth introducing into the teaching laboratory.
The determination of the solid–liquid phase diagram a binary system is always used as an experiment in undergraduate physical chemistry laboratory courses. However, most diagrams investigated lab are simple eutectic ones, despite fact that complex more common. In this article, cooling curves phenol–t-butanol mixtures measured and found to give three points two congruent melting points. provides students practical way investigate with their own efforts teamwork spirit.
Coronary artery anomalies (CAAs) are present at birth, but usually asymptomatic and found during coronary angiography or multi-slice computed tomography (MSCT) examinations. Their prevalence is less than 1.3% based published series.1,2 The most common anomaly separate origin of the left anterior descending (LAD) circumflex (LCX) from sinus Valsalva. second LCX right (RCA) We two cases anomalies: one main (LMCA) arising proximal RCA, other LAD originating RCA. A 67-year-old man presented with...
A correction is made for the calculation equation of aggregation numbers SDS at various temperatures proposed by Marcolongo and Mirenda in their paper “Thermodynamics Sodium Dodecyl Sulfate (SDS) Micellization: An Undergraduate Laboratory Experiment”.
The variation in the transference number of H+ (aq) is investigated for different HCl solution concentrations. method scribing graduations on electromigration tubes modified to decrease error experimental measurements, and metallic copper used as anode reduce toxicity environmental impact reagents. For very dilute solutions, correlation between concentration theoretically described using equations derived from Debye–Hückel–Onsager equation ionic molar conductivity, Longsworth's applied...
To introduce peratrial device closure of secundum atrial septal defects (ASD) under the guidance transesophageal echocardiography (TEE) without cardiopulmonary bypass (CPB) in children, and to summarize clinical experiences.A total 115 children with ASD (the occlusion group) underwent through a small sternotomy TEE bypass. Children were followed up closely for 1-13 months. Another 59 had closed during same period. The differences operation duration, convalescence complication between 2...
In the presence of catalytic amount cesium hydroxide, hydroselenation terminal alkynes occurred in N,N-dimethylformamide (DMF) at room temperature under nitrogen atmosphere to afford (E)-1-organseleno-1-alkene high yields.The reaction mechanism is that selenols reacted with hydroxide give selenides, which underwent nucleophilic addition form selenium vinylic anion, hydrolyzed product (E)-1-organoselenovinylene and catalyst hydroxide.The method could provide a new expedient way for...
e17517 Background: The aim of this study was to evaluate the efficacy and safety apanitib in treatment patients with recurrent and/or metastatic head neck squamous cell carcinoma (HNSCC) who failed from one or more lines therapy. Methods: Patients HNSCC after failure at least line therapy were recruited open-label exploratory study. Subjects initially given apatinib 250mg qd until disease progression unacceptable toxicity. Dose reduction 125 mg allowed. Herein, we reported preliminary...