To design an ensemble learning based prediction model using different breast DCE-MR post-contrast sequence images to distinguish two kinds of cancer subtypes (luminal and non-luminal). We retrospectively studied preoperative dynamic contrast enhanced-magnetic resonance imaging molecular information 266 cases with either luminal subtype A B) or non-luminal (human epidermal growth factor receptor 2 triple negative). Then, multiple bounding boxes covering tumor lesions were acquired from three...

Background Spontaneous coronary artery dissection (SCAD) significantly contributes to myocardial infarction among young individuals. Despite the elusive nature of its etiology, empirical evidence indicates a substantial correlation between sociopsychological factors and disorder. This investigation endeavored discern genetic basis for personality traits influencing SCAD susceptibility. Methods Bidirectional univariate multivariate Mendelian randomization (MR) analyses were hereby conducted...

In the past, due to improper sludge treatment technology and absence of standards, some municipal was simply dewatered then sent landfills, occupying a significant amount land posing serious threat secondary pollution. To free up in landfill area for expansion large-scale wastewater plant (WWTP) Shanghai, this study, we conducted comprehensive pilot research on entire chain reprocessing resource utilization. Both combination polyferric silicate sulfate (PFSS) polyetheramine (PEA)...

Abstract To assess the role of protein-energy malnutrition on perioperative outcomes in patients with pancreatic cancer undergoing open pancreaticoduodenectomy. We conducted a retrospective observational cohort study and investigated ≥ 18 years old pancreaticoduodenectomy within National inpatient sample database during 2012–2014. The population was divided into two groups based presence malnutrition. In-hospital mortality, length stay, cost hospitalization, in-hospital complications were...

Background Use of inpatient brain magnetic resonance imaging (MRI) in patients with acute ischemic stroke is highly institution dependent and has been associated increased length cost hospital stay. We examined whether MRI improved clinical outcomes to justify its resource requirements. Methods Results The National Inpatient Sample database was queried retrospectively find 94 003 who were admitted for then received between 2012 2014. Multivariable regression analysis performed respect a...

Leukoaraiosis (LA) is strongly associated with impaired cognition and increased dementia risk. Determining effective robust methods of identifying LA patients mild cognitive impairment (LA-MCI) important for clinical intervention disease monitoring. In this study, an ensemble learning method that combines multiple magnetic resonance imaging (MRI) morphological features proposed to distinguish LA-MCI from lacking (LA-nCI). Multiple comprehensive measures (including gray matter volume (GMV),...

Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) is an effective treatment of acute ischemic stroke (AIS). The safety intravenous rtPA in patients thrombocytopenia unclear. This study sought to evaluate the impact on in-hospital outcomes AIS who received thrombolysis.This was a retrospective using 2012-2014 National Inpatient Sample (20% stratified sample US hospitals). identified adult admitted during hospitalization. admissions were into 2 cohorts based...

To investigate relationships between the severity of white matter hyperintensities (WMH), functional brain activity, and cognition in cerebral small vessel disease (CSVD) based on resting-state magnetic resonance imaging (rs-fMRI) data.A total 103 subjects with CSVD were included. The amplitude low frequency fluctuations (ALFF), regional homogeneity (ReHo), connectivity (FC) their graph properties applied to explore influence WMH burden activity. We also investigated whether there are...

Objective. This study aims to develop a three-dimensional convolutional neural network utilizing computer-aided diagnostic technology facilitate the detection of intracranial aneurysms and automatically assess their location extent, thereby enhancing efficiency radiologists, streamlining clinical workflows.Approach. A retrospective was conducted, proposing joint segmentation classification (JSCD-Net) that employs 3D time-of-flight magnetic resonance angiography images for preliminary...

The primary aim of this study was to explore the safety and feasibility minimally invasive surgical device closure perimembranous ventricular septal defects (PMVSDs) in children using echocardiography for preoperative assessment intraoperative guidance.We enrolled 942 diagnosed with PMVSDs from April 2010 October 2013. All underwent full evaluation by transthoracic (TTE) multiplane transesophageal (MTEE) determine sizes, types spatial positions their proximity adjacent tissues. were...

Objective Cardiovascular (CV) diseases are serious comorbidities in patients with granulomatosis polyangiitis (GPA). In a sample of hospitalized for GPA, we sought to examine trends the burden coronary artery disease (CAD) and its 2 manifestations, acute myocardial infarction (AMI) heart failure (HF). Methods We used National Inpatient Sample conduct retrospective cross-sectional analysis. Our consisted hospitalizations GPA between 2005 2014. examined proportion CAD, AMI, HF all compared...

While magnetic resonance imaging (MRI) has higher sensitivity than computed tomography for certain types of traumatic brain injury (TBI), it remains unknown whether the increased detection intracranial injuries leads to improved clinical outcomes in acute TBI patients, especially given resource requirements involved performing MRI. We leveraged a large national patient database examine associations between MRI utilization and inpatient hospitalized patients.The National Inpatient Sample was...

Inflammatory myofibroblastic tumors (IMTs), also known as inflammatory pseudotumor are rarely reported in the trachea. Although initially considered benign, with recent evidence of local recurrence after surgical resection, cases metastatic spread, and advance cytogenetic analysis, they now categorized malignant potential. Correct histological diagnosis is utmost importance, closely resemble other benign spindle cell myofibroblasts predominance. Treatment remains challenging taking into...

Abstract Background Accurate segmentation of lung nodules is great significance for early screening and diagnosis cancer. Purpose However, the heterogeneity similarities between them other tissues make it difficult to accurately segment these nodules. As regards use deep learning nodules, convolutional neural networks would gradually lead errors accumulating at network layer due presence multiple upsampling downsampling layers, resulting in poor results. Methods In this study, we developed a...

To introduce a new technique to create pulmonary valve biorifice for the reconstruction of right ventricular outflow tract in tetralogy Fallot (TOF), and summarize initial clinical experiment.The reconstructing with was used 53 cases TOF (the observation group). While conventional other 50 control The Data all reviewed retrospectively.The ages, weights, cardiopulmonary bypass time, cardiac arrest as well post operation ventilation support time were not different significantly between groups....

Atrial fibrillation (AF) has been suggested as a cause for pulmonary embolism (PE). We aimed to explore the prevalence and clinical impact of AF in patients with PE.Using 2012-2014 National (Nationwide) Inpatient Sample database, we identified "adult PE" principal discharge diagnosis. The admissions were stratified into two cohorts based on presence or absence AF. used multivariable regression models evaluate in-hospital mortality, length stay, nonhome discharge, complications.The among...

This study investigated the feasibility, timing and indications for closure of large muscular ventricular septal defects (VSDs) in infants without use a cardiopulmonary bypass.A total 9 with VSDs ranging size from 7 to 15 mm were treated by minimally invasive bypass between April 2010 February 2013.All surgeries successful resulting uncontrolled systemic infection, pulmonary hypertensive crisis or severely low cardiac output, an apparently shorter operation time postoperative tracheal...

To elucidate the preoperative, intraoperative, and postoperative utility of echocardiographic technology in occlusion ventricular septal defect (VSD) via small chest incision.We performed VSD incision 446 children. Before surgery, a multiple-section transthoracic echo-cardiogram (TTE) was employed to evaluate various parameters (including size, position, type) region as well condition neighboring tissues. During surgery we reassured size occluder, meanwhile, guiding placement occluder by...