A5010007501- Galaxies: Formation, Evolution, Phenomena
- Adaptive optics and wavefront sensing
- Cosmology and Gravitation Theories
- Astronomy and Astrophysical Research
- MicroRNA in disease regulation
- Advanced Welding Techniques Analysis
- Autophagy in Disease and Therapy
- Gamma-ray bursts and supernovae
- Ubiquitin and proteasome pathways
- PI3K/AKT/mTOR signaling in cancer
- Cancer Mechanisms and Therapy
- Relativity and Gravitational Theory
- Pancreatic function and diabetes
- Cancer-related Molecular Pathways
- Mechanisms of cancer metastasis
- Cancer, Hypoxia, and Metabolism
- Magnesium Oxide Properties and Applications
- Retinoids in leukemia and cellular processes
- Innovative concrete reinforcement materials
- Body Contouring and Surgery
- Protein Degradation and Inhibitors
- Surface Treatment and Residual Stress
- Dark Matter and Cosmic Phenomena
- Inflammatory Biomarkers in Disease Prognosis
- Concrete and Cement Materials Research
Shanghai Jiao Tong University
2006-2024
Shanghai Astronomical Observatory
2022-2024
Nanjing Medical University
2020
Shanghai Ninth People's Hospital
2014-2018
Tsinghua University
2007
We here evaluated the potential anti-colorectal cancer activity by erastin, a voltage-dependent anion channel (VDAC)-binding compound. Our in vitro studies showed that erastin exerted potent cytotoxic effects against multiple human colorectal cell lines, possibly via inducing oxidative stress and caspase-9 dependent apoptosis. Further, mitochondrial permeability transition pore (mPTP) opening was observed erastin-treated cells, which evidenced VDAC-1 cyclophilin-D (Cyp-D) association,...
ABSTRACT Calibrating the redshift distributions of photometric galaxy samples is essential in weak lensing studies. The self-calibration method combines angular auto- and cross-correlations between galaxies multiple (photo-z) bins to reconstruct scattering rates matrix bins. In this paper, we test a recently proposed algorithm using DECaLS Data Release 9 investigate what extent are determined. We first mitigate spurious correlations due imaging systematics by machine learning based method....
Abstract The gravitational potential decay rate (DR) is caused by the cosmic acceleration of Universe, providing a direct probe into existence dark energy (DE). We present measurements DR and explore its implications for DE models using DR9 galaxy catalog Dark Energy Spectroscopic Instrument (DESI) imaging surveys Planck microwave background maps. Our analysis includes six redshift bins within range 0.2 ≤ z < 1.4 achieves total significance 3.1 σ , extending to much higher compared Dong...
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and effective therapy for human remains a difficult clinical concern. Researchers have demonstrated that microRNAs play important roles tumorigenesis tumor progression cancer; therefore, regulation may be new strategy HCC therapy. MicroRNA-196a (miR-196a) has been reported to overexpressed many types cancers. However, regulatory effects miR-196a are not fully understood. In present study, we found was...
Purpose: Myeloid derived suppressor cells (MDSC) play an important role in tumor immune evasion and its level significantly increased patients with gastric cancer. Studies confirmed the associations between MDSC various cytokines peripheral blood. However, little is known about mechanism drawing into parenchyma. This study was to analyze correlation subsets CCR5 cancer.Materials methods: G-MDSC M-MDSC from blood parenchyma were analyzed by flow cytometry. ligand CCL5 detected ELISA....
ABSTRACT Weak gravitational lensing induces flux-dependent fluctuations in the observed galaxy number density distribution. This cosmic magnification (magnification bias) effect principle enables reconstruction alternative to shear and microwave background lensing. However, intrinsic clustering, which otherwise overwhelms signal, has hindered its application. Through a scaling relation found by principal component analysis of clustering multiband photometry space, we design minimum variance...
Abstract Non-Gaussianity of the cosmological matter density field can be largely reduced by a local Gaussianization transformation (and its approximations, such as logarithmic transformation). Such behavior recast Gaussian copula hypothesis (GCH), and has been verified to very high accuracy at two-point level. On other hand, statistically significant non-Gaussianities in Gaussianized have detected simulations. We point out that this apparent inconsistency is caused limited degrees freedom...
In situ TiB w and La 2 O 3 reinforced titanium matrix composites were successfully fusion welded by the gas tungsten arc welding (GTAW) process weldability feasibility for studied, uniform defect free welds produced with sound parameters. Microstructural observations showed that joint has a distinctly identified weld zone characteristic. addition, distribution size of in became much more homogeneous smaller. Moreover, joints exhibited good mechanical properties at ambient temperature...
We numerically investigate non-Gaussianities in the late-time cosmological density field Fourier space. explore various statistics, including two-point and three-point probability distribution function (PDF) of phase modulus, two \& correlation modulus. detect significant non-Gaussianity for certain configurations. compare simulation results with theoretical expansion series \citet{2007ApJS..170....1M}. find that $\mathcal{O}(V^{-1/2})$ order term alone is sufficiently accurate to describe...
The gravitational potential decay rate (DR) is caused by the cosmic acceleration of universe, providing a direct probe into existence dark energy (DE). We present measurements DR and explore its implications for DE models using Data Release 9 galaxy catalog DESI imaging surveys Planck microwave background maps. Our analysis includes six redshift bins within range $0.2\le z<1.4$ achieves total significance 3.1$\sigma$, extending to much higher comparing Dong et al. (2022), which focused on...
In this study, we explore the reconstruction of lensing convergence $\ensuremath{\kappa}$ map using cosmic magnification effect in DECaLS galaxies from DESI imaging surveys DR9. This complementary approach provides valuable insights into large scale structure Universe alongside traditional shear measurements. It is achieved by linearly weighing 12 maps galaxy number overdensity different magnitude bins $grz$ photometry bands. The weight designed to eliminate mean deterministic bias, minimize...
In \citep{Qin+}, we attempted to reconstruct the weak lensing convergence map $\hat{\kappa}$ from cosmic magnification by linearly weighting DECaLS galaxy overdensities in different magnitude bins of $grz$ photometry bands. The is correlated with shear at 20-$\sigma$ significance. However, low number density survey prohibits measurement auto-correlation. this paper, apply reconstruction method Dark Energy Survey Year 3 (DES Y3) galaxies DES Data Release 2 (DR2). With greater depth and higher...
Alternative to weak lensing measurements through cosmic shear, we present a convergence $\hat{\kappa}$ map reconstructed magnification effect in DECaLS galaxies of the DESI imaging surveys DR9. This is achieved by linearly weighing $12$ maps galaxy number overdensity different magnitude bins $grz$ photometry bands. The weight designed eliminate mean deterministic bias, minimize shot noise while maintaining signal. We also perform corrections systematics overdensity. has $8365$ deg$^2$ sky...
Objective: To observe the G protein-coupled receptor 48 (GPCR48) expression in hepatocellular carcinoma (HCC) cell lines with different metastatic potential and its characteristics effect on invasion metastasis of Huh7 hepatoma cells via epithelial-mesenchymal transition (EMT). Methods: Western blot was used to detect protein level GPCR48 HCC potential. The lentivirus vector expressing gene constructed. overexpressed cells. overexpression detected by real-time PCR blot. Transwell migration...
Weak gravitational lensing induces flux dependent fluctuations in the observed galaxy number density distribution. This cosmic magnification (magnification bias) effect principle enables reconstruction alternative to shear and CMB lensing. However, intrinsic clustering, which otherwise overwhelms signal, has hindered its application. Through a scaling relation found by principal component analysis of clustering multi-band photometry space, we design minimum variance linear estimator suppress...
To study the effect of histone deacetylase inhibitor to osteosarcoma by targeting specificity protein 1 and regulating Phospholipase D1. Human cell line MG63 cells were cultured in Dulbecco’s Modified Eagle’s medium containing penicillin (100 U/ml) 10 % fetal bovine serum at 37°. siRNA-specificity psiCHECK-Phospholipase-WT plasmid constructed transfected into cells. Dual luciferase reporter gene assay conducted verified combination site Phospholipase. treated with tumor-specific antigen (5...