Ariadna Sánchez

ORCID: 0000-0003-0409-1328
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About
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Research Areas
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Screening and Detection
  • Cancer Genomics and Diagnostics
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal disorders and treatments
  • Pancreatic and Hepatic Oncology Research
  • Speech Recognition and Synthesis
  • Colorectal and Anal Carcinomas
  • Helicobacter pylori-related gastroenterology studies
  • Multiple and Secondary Primary Cancers
  • Natural Language Processing Techniques
  • Topic Modeling
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Colorectal Cancer Treatments and Studies
  • Diverticular Disease and Complications
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Eosinophilic Disorders and Syndromes
  • Veterinary medicine and infectious diseases
  • Nail Diseases and Treatments
  • Microscopic Colitis
  • Colorectal Cancer Surgical Treatments
  • Pancreatitis Pathology and Treatment
  • Trigeminal Neuralgia and Treatments
  • Congenital gastrointestinal and neural anomalies
  • Magnesium in Health and Disease

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2016-2025

Hospital Clínic de Barcelona
2012-2025

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2016-2025

Universitat de Barcelona
2016-2025

Hospital General Universitario de Albacete
2025

Karolinska University Hospital
2023

Karolinska Institutet
2023

Vall d'Hebron Institut de Recerca
2023

Vall d'Hebron Hospital Universitari
2023

Amazon (United Kingdom)
2022

Mev Dominguez–Valentin Julian R. Sampson Toni T. Seppälä Sanne W. ten Broeke John‐Paul Plazzer and 83 more Sigve Nakken Christoph Engel Stefan Aretz Mark A. Jenkins Lone Sunde Inge Bernstein Gabriel Capellá Francesc Balaguer Huw Thomas D. Gareth Evans John Burn Marc S. Greenblatt Eivind Hovig Wouter H. de Vos tot Nederveen Cappel Rolf H. Sijmons Lucio Bertario Maria Grazia Tibiletti Giulia Martina Cavestro Annika Lindblom Adriana Della Valle Francisco López‐Köstner Nathan Gluck Lior H. Katz Karl Heinimann Carlos Vaccaro Reinhard Büttner Heike Görgens Elke Holinski‐Feder Monika Morak Stefanie Holzapfel Robert Hüneburg Magnus von Knebel Doeberitz Markus Loeffler Nils Rahner Hans K. Schackert Verena Steinke‐Lange Wolff Schmiegel Deepak Vangala Kirsi Pylvänäinen Laura Renkonen‐Sinisalo John L. Hopper Aung Ko Win Robert W. Haile Noralane M. Lindor Steven Gallinger Loı̈c Le Marchand Polly A. Newcomb Jane C. Figueiredo Stephen N. Thibodeau Karin Wadt Christina Therkildsen Henrik Okkels Zohreh Ketabi Leticia Moreira Ariadna Sánchez Miquel Serra‐Burriel Marta Pineda Matilde Navarro Ignacio Blanco Kate Green Fiona Lalloo Emma J. Crosbie James Hill Oliver G. Denton Ian M. Frayling Einar Andreas Rødland Hans F. A. Vasen Miriam Mints Florencia Neffa Patricia Esperón Karin Álvarez Revital Kariv Guy Rosner Tamara Alejandra Piñero María Laura González Pablo Kalfayan Douglas Tjandra Ingrid Winship Finlay Macrae Gabriela Möslein Jukka‐Pekka Mecklin Maartje Nielsen Pål Møller

Pathogenic variants affecting MLH1, MSH2, MSH6, and PMS2 cause Lynch syndrome result in different but imprecisely known cancer risks. This study aimed to provide age organ-specific risks according gene gender determine survival after cancer.We conducted an international, multicenter prospective observational using independent test validation cohorts of carriers class 4 or 5 variants. After the were merged providing 6350 participants 51,646 follow-up years.There 1808 prospectively observed...

10.1038/s41436-019-0596-9 article EN cc-by-nc-sa Genetics in Medicine 2019-07-23

Abstract Artificial Intelligence ( ai ) systems are precious support for decision-making, with many applications also in the medical domain. The interaction between md s and enjoys a renewed interest following increased possibilities of deep learning devices. However, we still have limited evidence-based knowledge context, design, psychological mechanisms that craft an optimal human– collaboration. In this multicentric study, 21 endoscopists reviewed 504 videos lesions prospectively acquired...

10.1038/s41598-022-18751-2 article EN cc-by Scientific Reports 2022-09-02
Mev Dominguez–Valentin Saskia Haupt Toni T. Seppälä Julian R. Sampson Lone Sunde and 95 more Inge Bernstein Mark A. Jenkins Christoph Engel Stefan Aretz Maartje Nielsen Gabriel Capellá Francesc Balaguer D. Gareth Evans John Burn Elke Holinski‐Feder Lucio Bertario Bernardo Bonanni Annika Lindblom Zohar Levi Finlay Macrae Ingrid Winship John‐Paul Plazzer Rolf H. Sijmons Luigi Laghi Adriana Della Valle Karl Heinimann Tadeusz Dębniak Robert Fruscio Francisco Lopez-Koestner Karin Alvarez-Valenzuela Lior H. Katz Ido Laish E Vainer Carlos Vaccaro Dirce Maria Carraro Kevin Monahan Elizabeth Half Áine Stakelum D. C. Winter Rory Kennelly Nathan Gluck Harsh Sheth Naim Abu‐Freha Marc S. Greenblatt Bernard Rossi Mábel Bohórquez Giulia Martina Cavestro Leonardo S. Lino‐Silva Karoline Horisberger Maria Grazia Tibiletti Ivana do Nascimento Huw Thomas Norma Rossi Leandro Apolinário da Silva Attila Zaránd Juan Ruiz‐Bañobre Vincent Heuveline Jukka‐Pekka Mecklin Kirsi Pylvänäinen Laura Renkonen‐Sinisalo Anna Lepistö Païvi Peltomäki Christina Therkildsen Mia Gebauer Madsen Stefan Kobbelgaard Burgdorf John L. Hopper Aung Ko Win Robert W. Haile Noralane M. Lindor Steven Gallinger Loı̈c Le Marchand Polly A. Newcomb Jane C. Figueiredo Daniel D. Buchanan Stephen N. Thibodeau Magnus von Knebel Doeberitz Markus Loeffler Nils Rahner Evelin Schröck Verena Steinke‐Lange Wolff Schmiegel Deepak Vangala Claudia Perne Robert Hüneburg Silke Redler Reinhard Büttner Jürgen Weitz Marta Pineda Núria Dueñas Joan Brunet Leticia Moreira Ariadna Sánchez Eivind Hovig Sigve Nakken Kate Green Fiona Lalloo James Hill Emma J. Crosbie Miriam Mints Yael Goldberg

10.1016/j.eclinm.2023.101909 article EN cc-by EClinicalMedicine 2023-03-20

Background and Study Aims: The aim of this study was to assess the safety usefulness capsule endoscopy (CE) in pediatric patients with a suspicion Crohn’s disease. Patients Methods: CE used 12 (four girls, eight boys; age - 16; weight range 43 87 kg). indication clinical disease not confirmed traditional methods. Gastroscopy, colonoscopy, small-bowel follow-through examinations were carried out all patients, without any diagnostic findings. Ileoscopy possible 50 % ileal mucosa biopsies normal cases.

10.1055/s-2004-825854 article EN Endoscopy 2004-09-28

Accurate in-vivo optical characterization of colorectal polyps is key to select the optimal treatment regimen during colonoscopy. However, reported accuracies vary widely among endoscopists. We developed a novel intelligent medical device able seamlessly operate in real-time using conventional white light (WL) endoscopy video stream without virtual chromoendoscopy (blue light, BL). In this work, we evaluated standalone performance computer-aided diagnosis (CADx) on prospectively acquired...

10.1038/s41746-022-00633-6 article EN cc-by npj Digital Medicine 2022-06-30

Colonoscopy is one of the methods choice for screening relatives patients with colorectal cancer.To evaluate rate adherence to colonoscopy in first-degree cancer and describe lesions found.A prospective, cross-sectional, multicentre, nationwide study was conducted. The population composed selected randomly from EPICOLON study. Seventy-four index were included. These had 342 living (parents, siblings children), whom 281 interviewed.The 38% (107/281). Adherence greater families a higher degree...

10.1136/gut.2007.120709 article EN Gut 2007-03-31

Background and study aims Serrated polyposis syndrome (SPS) is a high risk condition for colorectal cancer (CRC). Surveillance strategies patients with serrated lesions remain controversial. We aimed to evaluate diagnostic strategy detect SPS consistently during reassessment colonoscopy in proximal lesions. Methods This was retrospective of all individuals from fecal immunochemical test (FIT)-based CRC screening program (2010 - 2013) one or more ≥ 5 mm the sigmoid colon on baseline...

10.1055/s-0042-115640 article EN Endoscopy 2016-10-14

To establish the optimal time to start oral refeeding in mild and moderate acute pancreatitis (AP) reduce hospital length-of-stay (LOS) complications.

10.1097/sla.0000000000004596 article EN Annals of Surgery 2020-11-17

Abstract Background The incidence of early-onset colorectal cancer is increasing, but in Europe this growth shows a heterogeneous pattern different countries and regions. Methods Patients from six who participated the Global Early-Onset COlorectal Cancer DatabasE (GEOCODE)-Europe group were included. inclusion criteria patients with adenocarcinoma diagnosed between 18 49 years age, January 2010 December 2017, at least 3 follow-up. inherited syndromes excluded. Results A total 851 included...

10.1093/bjsopen/zraf024 article EN cc-by-nc BJS Open 2025-03-04
Kristina Zalevskaja K. Ojala А. Н. Петров Saskia Haupt Lone Sunde and 95 more Inge Bernstein Mark A. Jenkins Stefan Aretz Maartje Nielsen Gabriel Capellá Francesc Balaguer D. Gareth Evans John Burn Elke Holinski‐Feder Lucio Bertario Bernardo Bonanni Annika Lindblom Zohar Levi Finlay Macrae Ingrid Winship J-P Plazzer Rolf H. Sijmons Luigi Laghi Adriana Della Valle Karl Heinimann Tadeusz Dębniak Robert Fruscio Francisco Lopez-Koestner Karin Alvarez-Valenzuela Lior H. Katz Ido Laish E Vainer Carlos Vaccaro Dirce Maria Carraro Kevin Monahan Elizabeth Half Áine Stakelum D. C. Winter Rory Kennelly Nathan Gluck Harsh Sheth Naim Abu‐Freha Marc S. Greenblatt Bernard Rossi M Bohorquez Giulia Martina Cavestro Leonardo S. Lino‐Silva Karoline Horisberger Maria Grazia Tibiletti Ivana do Nascimento Huw Thomas Norma Rossi L A da Silva Attila Zaránd Juan Ruiz‐Bañobre Vincent Heuveline Lars Joachim Lindberg Ismail Gögenür John L. Hopper Aung Ko Win Robert W. Haile Noralane M. Lindor Steven Gallinger Loı̈c Le Marchand Polly A. Newcomb Jane C. Figueiredo Daniel D. Buchanan Stephen N. Thibodeau Magnus von Knebel Doeberitz Markus Loeffler Nils Rahner Evelin Schröck Verena Steinke‐Lange Wolff Schmiegel Deepak Vangala Claudia Perne Robert Hüneburg Silke Redler Reinhard Büttner Jürgen Weitz Marta Pineda Núria Dueñas Joan Brunet Leticia Moreira Ariadna Sánchez J Castillo-Iturra Eivind Hovig K Green Fiona Lalloo James Hill Emma J. Crosbie Miriam Mints Yael Goldberg Douglas Tjandra Sanne W. ten Broeke Revital Kariv Guy Rosner Avni Jain P Shah Mitul Shah

This first prospective observational study evaluates the impact of extended versus segmental colorectal surgery on risk metachronous cancer (CRC) in patients with Lynch syndrome, analyzing data from Prospective Syndrome Database version 5. Extended resection significantly reduced CRC path_MLH1, path_MSH2, and path_MSH6 carriers compared to resection.

10.1093/bjs/znaf061 article EN cc-by British journal of surgery 2025-03-28

Patients' psychological reactions to multigene cancer panel testing might differ compared with the single-gene because of complexity and uncertainty associated different possible results. Understanding patients' preferences impact is important adapt genetic counselling model.One hundred eighty-seven unrelated patients clinical suspicion hereditary undergoing a 25-gene test completed questionnaires after pretest at 1 week, 3 months, 12 months results elicit their regarding disclosure measure...

10.1002/pon.4686 article EN Psycho-Oncology 2018-03-02

Abstract Background Serrated polyposis syndrome (SPS) has been associated with an increased risk of colorectal cancer (CRC). Accordingly, intensive surveillance annual colonoscopy is advised. The aim this multicenter study was to describe the advanced lesions in SPS patients undergoing surveillance, and identify factors that could guide prevention strategy. Methods From March 2013 April 2015, 296 who fulfilled criteria I and/or III for were retrospectively recruited at 18 centers. We...

10.1055/a-0656-5557 article EN Endoscopy 2018-08-01

10.1016/j.cgh.2019.08.035 article EN Clinical Gastroenterology and Hepatology 2019-08-22

Early‐onset (<50 years‐old) nonpolyposis nonfamilial colorectal cancer (EO NP NF CRC) is a common clinical challenge. Although Lynch syndrome (LS) associated with EO CRC, the frequency of this in cases remains unknown. Besides, mismatch repair deficient (MMRd) CRCs negative MMR gene testing have recently been described up to 60% and termed “Lynch‐like syndrome” (LLS). Management counseling decisions these patients are complicated because unconfirmed suspicions hereditary cancer. To define...

10.1002/ijc.32160 article EN International Journal of Cancer 2019-01-29

Gastric adenocarcinoma (GC) is a common tumor with high morbidity and mortality. Only 7% of patients GC are diagnosed before age 50 (early onset gastric cancer (EOGC)), their characteristics have been poorly described. We aimed to describe clinical, molecular, genetic EOGC. A total 309 EOGC were retrospectively studied in four Spanish centers. Personal information, family history, information registered. Germinal analysis was performed who met current criteria hereditary syndrome at the time...

10.3390/cancers13133132 article EN Cancers 2021-06-23
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