- COVID-19 Clinical Research Studies
- Cardiac Imaging and Diagnostics
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Kawasaki Disease and Coronary Complications
- Orthopedic Infections and Treatments
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Emergency and Acute Care Studies
- Neonatal and Maternal Infections
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Maternal and Perinatal Health Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Vaccine Coverage and Hesitancy
- Maternal and fetal healthcare
- Respiratory viral infections research
- Viral-associated cancers and disorders
- Cancer Diagnosis and Treatment
Aga Khan University Nairobi
2021-2024
Aga Khan University Hospital Nairobi
2022-2023
PURPOSE Antiretroviral therapy (ART) has resulted in a higher life expectancy of persons living with HIV. This led to an aging population at risk for both non–AIDS-defining cancers (NADCs) and AIDS-defining (ADCs). HIV testing among patients cancer Kenya is not routinely performed, making its prevalence undefined. The aim our study was determine the spectrum malignancies HIV-positive HIV-negative attending tertiary hospital Nairobi, Kenya. MATERIALS AND METHODS We conducted cross-sectional...
Among therapeutic options for severe and critical COVID- 19 infection, dexamethasone six milligrams once daily ten days has demonstrated mortality benefit is guideline recommended at this dose. In practice, variable doses of steroids have been used, especially in care settings. Our study aimed to determine the pattern steroid dosing outcomes terms mortality, occurrence dysglycaemias, superadded infections patients with COVID-19.
The aim of our study was to outline the burden, risk factors, and outcomes for critical COVID-19 patients with coinfections or superinfections.This a retrospective descriptive adults who were admitted ≥ 24 hours. Data collected included demographic profiles other baseline characteristics, laboratory radiological investigations, medical interventions, clinical outcomes. Outcomes interest presence absence superinfections, in-hospital mortality. Differences between those without superinfections...
Abstract Background Lower respiratory tract infections continue to contribute significantly morbidity and mortality across all age groups globally. In sub-Saharan Africa, many studies of community acquired pneumonia in adults have focused on HIV-infected patients little attention has been given risk factors etiologic agents an urban area with a more moderate HIV prevalence. Methods We prospectively enrolled 77 admitted 280 bed teaching hospital Kenya radiographically confirmed from May 2019...
A 52 year old female presented with a one month history of progressive back pain radiating to the right lower limb. She reported unintentional weight loss seven kilograms over three months and drenching night sweats. There was no cough. Her physical examination unremarkable. HIV ELISA test positive. CD4 count 27 cells/mm3 viral load 1.8 million copies/ml. An MRI spine (A,B) evaluate revealed single spinal ring enhancing lesion at T12 minimal perilesional edema. chest CT scan in keeping...
Background Acute COVID-19-related myocardial, pulmonary, and vascular pathology how these relate to each other remain unclear. To our knowledge, no studies have used complementary imaging techniques, including molecular imaging, elucidate this. We multimodality biochemical sampling in vivo identify the pathobiology of acute COVID-19. Specifically, we investigated presence myocardial inflammation its association with coronary artery disease, systemic vasculitis, pneumonitis. Methods Results...
Intestinal tuberculosis (ITB) constitutes less than 5% of overall cases extrapulmonary disease and mostly affects the ileocecal region. The presentation radiologic findings in enteric can mimic Crohn's (CD). Case Presentation. We present a case report an African woman who presented to Kenyan hospital with lower gastrointestinal bleeding while on anticoagulation for valvular atrial fibrillation, was diagnosed intestinal after colonoscopy, biopsy, positive staining tuberculous...
Data on antimicrobial resistance (AMR) and association with outcomes in resource-variable intensive care units (ICU) are lacking. currently available limited to large, urban centers. We attempted understand this locally through a dual-purpose, retrospective study. Cohort A consisted of adult pediatric patients who had blood, urine, or cerebrospinal fluid cultures obtained from 2016 2020. total 3,013 isolates were used create the Kijabe Hospital's first antibiogram. Gram-negative organisms...
Importance: Acute COVID19 related myocardial, pulmonary and vascular pathology, how these relate to each other, remains unclear. No studies have used complementary imaging techniques, including molecular imaging, elucidate this. Objective: We multimodality biochemical sampling in vivo identify the pathobiology of acute COVID19. Design, Setting Participants: Consecutive patients presenting with were recruited during hospital admission a prospective cross sectional study. Imaging involved...