- Organ Transplantation Techniques and Outcomes
- Diabetes Management and Research
- Diabetes and associated disorders
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Pancreatic function and diabetes
- Renal Transplantation Outcomes and Treatments
- Pregnancy-related medical research
- Liver Disease and Transplantation
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- Trigeminal Neuralgia and Treatments
- Ferroptosis and cancer prognosis
- Liver physiology and pathology
- Botulinum Toxin and Related Neurological Disorders
- Respiratory Support and Mechanisms
- Facial Nerve Paralysis Treatment and Research
- Lipid metabolism and disorders
- Immune cells in cancer
- Traditional Chinese Medicine Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Metabolism, Diabetes, and Cancer
- Hemostasis and retained surgical items
- Gestational Diabetes Research and Management
- Menopause: Health Impacts and Treatments
First Hospital of China Medical University
2003-2024
China Medical University
2003-2024
Nanfang Hospital
2009-2023
Southern Medical University
2009-2023
Peking University People's Hospital
2018-2021
Peking University
2018-2021
Zhujiang Hospital
2019
Shanghai Maritime University
2017-2019
Second Affiliated Hospital of Nantong University
2013-2015
Nantong University
2013-2015
Diabetic peripheral neuropathy (DPN) is one of the most common microvascular complications diabetes. Glycemic variability could be an independent risk factor for diabetes in addition to average glucose. Type 2 with well-controlled glycosylated hemoglobin A1c (HbA1c) may have different terms glycemic and vascular complication consequences. The aim study investigate relationship between DPN type HbA1c (HbA1c < 7.0%).45 HbA1c(HbA1c 7.0%) (DM/DPN group) were recruited study, 45 without (DM/-DPN...
Glucose variability could be an independent risk factor for diabetes complications in addition to average glucose. The deficiency islet β cell secretion and insulin sensitivity, the two important pathophysiological mechanisms of diabetes, are responsible glycemic disorders. oral disposition index evaluated by product sensitivity is a useful marker function. aim study investigate relation subjects across range glucose tolerance from normal overt type 2 diabetes.75-g test (OGTT) was performed...
Cell division cycle-associated 8 (CDCA8) is involved in numerous signaling networks, and it serves a crucial modulatory function multiple malignant tumors. However, its significance prognosis immune infiltration hepatocellular carcinoma (HCC) remains unclear.Herein, we examined the CDCA8 levels tumor tissues, as well associated pathways correlation with infiltration. Additionally, further clarified prognostic of among HCC patients. patient information was recruited from The Cancer Genome...
Treatment with cisplatin (DDP) is one of the standard therapies used to treat non-small-cell lung cancer (NSCLC) and fundamentally causes resistance in cells, which eventually poses as an obstacle efficacy chemotherapy NSCLC. Efforts are on all over world explore a sensitizer NSCLC DDP. Here, we studied effect IL-7 chemotherapy. We observed that treatment significantly enhanced DDP-induced effects A549 A549/DDP cells (DDP-resistant cells), including decreased cell viability proliferation,...
Women with previous gestational diabetes mellitus (pGDM) and postpartum normal glucose tolerance (NGT) may carry impaired islet β cell secretion, insulin resistance subsequent altered homeostasis. And certain normoglycemic groups at risks of were presented elevated glycemic variability. The aim study was to investigate the variability in NGT women pGDM.Total 48 pGDM (pGDM group) age- BMI-matched without (control recruited study. Integrated function assessed Insulin Secretion-Sensitivity...
To investigate the effect of sivelestat sodium on survival, oxygenation index, and serum markers for infection in critically ill patients with COVID-19-associated acute respiratory distress syndrome (ARDS).This retrospectively study was performed among ARDS admitted intensive care unit (ICU) at Nanfang Hospital, Southern Medical University. We collected clinical data first day ICU admission discharge laboratory tests results interleukin-6 (IL-6), C-reactive protein (CRP) procalcitonin (PCT)...
Objective: To explore the clinical characteristics of patients with persistent or recurrent hemifacial spasm (HFS) and experience microvascular decompression (MVD) in treatment such to accumulate additional evidence for optimal protocols. Methods: We retrospectively analyzed data, surgical methods efficacies 176 HFS from January 2009 2018. Results: Missing compression zones was main reason symptom persistence (87.50%) recurrence (71.50%) after MVD HFS. divided area into three zones. Most...
Summary It is generally impossible to analytically solve the Hamilton‐Jacobi‐Bellman (HJB) equation of an optimal control system. With coming big‐data era, this paper first derives a new data‐driven and model‐free Hamilton function for HJB equation. Then, tracking differentiator method proposed function. Finally, simulation classic example shows that policy can be approximated with method. Thus, online approximate solution achieved. This only driven by measured system states. All other...
This study aimed to examine the correlation between alterations in serum sex hormones testosterone (T) and estradiol (E2) early stages after craniocerebral extracranial injuries, assess Injury Severity Score (ISS) Glasgow Coma Scale (GCS) score patients with multiple investigate significance of posttrauma changes ISS GCS as well their ratio.The levels T E(2) 95 injuries trauma (within 24 hours) were determined by radioimmune double-antibody method. All classified ISS, among them, those...
Oxidized cellulose is available in many forms, but manufactured using either a regenerated or non-regenerated process. In this study, we evaluated the effects of 2 different hemostatic agents for treatment local bleeding patients undergoing hepatic resection.This was monocentric, parallel-group, randomized, and controlled clinical trial to compare oxidized gauze (ORCG) with (ONRCG) hepatectomy. The primary endpoint time hemostasis at target site. secondary endpoints were postoperative...
Doublet or triplet chemotherapy plus minus targeted drugs can achieve a high objective response rate (ORR) and are currently considered to be the backbone of conventional therapy for liver metastatic colorectal cancer (mCRC). However, current biomarkers (such as UGT1A1 DPYD) limited prediction toxicity there no effective predict response. Therefore, personalized underpinned by genomic alterations in mCRC has received increasing attention. We present case 28-year-old female rectal patient...
Objective To investigate the significance of standard deviation blood glucose in continuous monitoring subjects across a range tolerance from normal to overt type 2 diabetes.Methods Totally 220 were recruited study,including 47 with regulation (NGR),52 impaired (IGT,20 isolated tolerance,and 32 IGT and fasting glucose),61 diabetes diagnosed by h plasma (DM2h),and 60 newly both (DM).All monitored using system for consecutive 72 hours.The multiple parameters glycemic variability included...
Objective To evaluate the effect of islet transplantation for patients with type 2diabetes mellitus (DM). Methods Since December 2007, 4 cases transplantations were performed on 3 2 DM and end-stage renal disease (ESRD). Two received simultaneous islet-kidney transplant from single-donor (SIK), one consecutive transplants 5 months following kidney transplantion (IAK). All recipients given insulin a dose percutaneous transhepatic portal catheterization. Anti-CD25 monoclonal antibody was used...
Objective To summarize our experience in the liver transplantation from donation after cardiac death (DCD).Methods The livers three DCD donors (2 cases of brain trauma and 1 case cerebral hemorrhage) were harvested according to Guidelines for Donation Cardiac Death China.These grafts orthotopically transplanted into recipients including 2 decompensative hepatic cirrhosis primary cancer.The warm ischemic time ranged 7.5 10 min cold was 4.5,8.2 6.5 h respectively.Postoperative...
Objective To summarize the clinical experience of harvesting and using kidneys from donation after cardiac death (DCD) donors.Methods Fourteen kidney transplantations were successfully performed on 14 patients with end-stage renal diseases.The harvested 7 volunteer donors (age 30~53 years) diagnosed death,who scored 19~23according to University Wisconsin evaluation.Primary diseases cerebral hemorrhage,brain injury,ischemic vascular disease brain tumor.Warm ischemia time ranged 5 45 min,and...
Objective: Hemorrhagic transformation (HT) is common complication after mechanical thrombectory (MT) for acute ischemic stroke (AIS). To our knowledge, there has been no study on the correlation between baseline red blood cell distribution width (RDW) to platelet ratio (RPR) and HT MT. Methods: This recruited 126 AIS patients with anterior or posterior circulation large-vessel occlusion who underwent MT therapy at Department of Neurology, Taizhou Hospital, Zhejiang province September 2019...