A5100332372- Luminescence Properties of Advanced Materials
- Inorganic Chemistry and Materials
- Nanoparticle-Based Drug Delivery
- Micro and Nano Robotics
- Luminescence and Fluorescent Materials
- Advanced Polymer Synthesis and Characterization
- Advanced Photocatalysis Techniques
- Nanoplatforms for cancer theranostics
- Genomics and Phylogenetic Studies
- Catalytic C–H Functionalization Methods
- Cancer-related molecular mechanisms research
- Molecular Communication and Nanonetworks
- MXene and MAX Phase Materials
- Advanced Drug Delivery Systems
- Crystallization and Solubility Studies
- RNA Research and Splicing
- RNA Interference and Gene Delivery
- Analytical Chemistry and Chromatography
- Microbial Natural Products and Biosynthesis
- Advanced Materials and Mechanics
- Electrohydrodynamics and Fluid Dynamics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Molecular Sensors and Ion Detection
- X-ray Diffraction in Crystallography
- Pickering emulsions and particle stabilization
Eindhoven University of Technology
2003-2025
Chinese Academy of Sciences
2022-2025
Xinjiang Technical Institute of Physics & Chemistry
2024-2025
Institute of Macromolecular Chemistry
2025
East China University of Science and Technology
2021-2024
Beihang University
2024
Lanzhou Institute of Chemical Physics
2022-2024
Danish National Research Foundation
2024
Technical University of Denmark
2024
The Velux Foundations
2024
The luminescence properties of Eu2+-activated alkaline-earth silicon-oxynitrides have been studied. In the BaO−SiO2−Si3N4 system, a new BaSi2O2N2 compound was obtained having monoclinic structure with lattice parameters = 14.070(4) Å, b 7.276(2) c 13.181(3) β 107.74(6)°. All MSi2O2-δN2+2/3δ:Eu2+ (M Ca, Sr, Ba) materials can be efficiently excited in UV to visible region (370−460 nm), making them attractive as conversion phosphors for LED applications. A blue-green emission at 490−500 is...
The crystal structure and photoluminescence properties of undoped Ce3+-doped CaAlSiN3 as well the application white-light LEDs are reported. CaAlSiN3:Ce3+ have been synthesized, starting from Ca3N2, AlN, Si3N4, CeN or CeO2 with without Li3N, by a solid state reaction at 1700 °C for 4 h under high purity nitrogen atmosphere. Instead an ideal CaAlSiN3, more appropriate formula is proposed to be CaAl1−4δ/3Si1+δN3 (δ ≈ 0.3−0.4) Al/Si ratio about 1:2 on basis bond valence sum calculations, in...
Abstract Cyclin D1 is one of the most important oncoproteins that drives cancer cell proliferation and associates with tamoxifen resistance in breast cancer. Here, we identify a lncRNA, DILA1, which interacts overexpressed tamoxifen-resistant cells. Mechanistically, DILA1 inhibits phosphorylation at Thr286 by directly interacting blocking its subsequent degradation, leading to protein Knocking down decreases expression, growth restores sensitivity both vitro vivo. High expression associated...
Various autonomous or assisted driving strategies have been facilitated through the accurate and reliable perception of environment around a vehicle. Among commonly used sensors, radar has usually considered as robust cost-effective solution even in adverse scenarios, e.g., weak/strong lighting bad weather. Instead considering to fuse unreliable information from all available pure data becomes valuable alternative that is worth exploring. In this paper, we propose deep object detection...
Divalent europium-activated β-sialon (, ) phosphors with dopant concentration varying in the range of were synthesized by firing powder mixture , AlN, and at for under a nitrogen-gas pressure . The phase purity, microstructure, luminescence spectra, thermal quenching fired investigated. samples lower values showed higher finer more uniform particle size, emission. Green was achieved β-sialons upon near-ultraviolet (NUV) or blue-light excitations. Furthermore, had small quenching, emission...
Zika virus (ZIKV) infection is an emerging pandemic threat to humans that can be fatal in newborns. Advances digital health systems and nanoparticles facilitate the development of sensitive portable detection technologies for timely management viral infections. Here we report a nanomotor-based bead-motion cellphone (NBC) system immunological ZIKV. The presence testing sample results accumulation platinum (Pt)-nanomotors on surface beads, causing their motion H2O2 solution. Then concentration...
A convenient visible-light-induced method for the synthesis of thiocarbamates from isocyanides, thiols, and water has been developed under mild reaction conditions. The present protocol offers a cost-effective operationally straightforward approach to various in moderate good yields by simple use cheap Rose Bengal as photocatalyst reagent well an environmentally benign cosolvent.
Abstract Synthetic micro/nanomotors have been extensively exploited over the past decade to achieve active transportation. This interest is a result of their broad range potential applications, from environmental remediation nanomedicine. Nevertheless, it still remains challenge build fast-moving biodegradable polymeric nanomotor. Here we present light-propelled nanomotor by introducing gold nanoparticles (Au NP) onto bowl-shaped polymersomes (stomatocytes) via electrostatic and hydrogen...
Abstract Precise and timely recognition of hazardous chemical substances is great significance for safeguarding human health, ecological environment, public security, etc., especially crucial adopting appropriate disposition measures. Up to now, there remains a practical challenge sensitively detect differentiate organic amines with similar structures intuitive analysis outcomes. Here, unique optical probe two electrophilic sites rapid ultra‐sensitive ratiometric fluorescence detection...
The cytoskeleton is a crucial determinant of mammalian cell structure and function, providing mechanical resilience, supporting the membrane orchestrating essential processes such as division motility. Because its fundamental role in living cells, developing reconstituted or artificial major interest. Here we present an approach to construct that imparts support regulates dynamics. Our system involves amylose-based coacervates stabilized by terpolymer membrane, with formed from...
The morphology of nanodrugs is utmost importance in photothermal therapy because it directly influences their physicochemical behavior and biological responses. However, clarifying the inherent relationship between resultant properties remains challenging, mainly due to limitations flexible morphological regulation nanodrugs. Herein, we created a range morphologically controlled nanoassemblies based on poly(ethylene glycol)-block-poly(d,l-lactide) (PEG–PLA) block copolymer building blocks,...
Abstract The development of nanomedicines for autonomous motion‐promoted deep tumor treatment without the generation inflammatory damage to normal tissues remains an extreme challenge. Herein, design oxygen/heat dual‐driven stomatocyte nanomotor is showcased by integrating gold (Au) nanoparticles (NPs) and cerium oxide (CeO 2‐x ) NPs into artificial stomatocytes (Ce/Au‐Stomatocytes) that are further coated with cancer cell membranes (CM). prepared Ce/Au‐Stomatocytes anisotropic morphology...
The RNA-binding protein Lin28 is known to promote malignancy by inhibiting the biogenesis of let-7, which functions as a tumor suppressor. However, role Lin28/let-7 axis in epithelial-to-mesenchymal transition (EMT) and stemness breast cancer has not been clearly expatiated. In our previous study, we demonstrated that let-7 regulates self-renewal tumorigenicity stem cells. present was highly expressed mesenchymal (M) type cells (MDA-MB-231 SK-3rd), but it barely detectable epithelial (E)...
A method for Pd-catalyzed aerobic oxidative reaction of quinazolinones and alkynes has been developed sequential [4 + 2] [3 cycloadditions to assemble a novel fused-polycyclic system containing tetrahydropyridine dihydrofuran rings. The process involves C–H N–H bond functionalization the formation an oxygen radical cyclization ring. This atom- step-economical synthesis is highly efficient good substrate tolerance, which provides new approach construction polycyclic molecules with potential...
Many patients with breast cancer still relapse after curative treatment. How to identify the ones high risk remains a critical problem. Circulating tumor DNA (ctDNA) has recently become promising marker monitor burden. Whether ctDNA can be used predict response and prognosis in receiving neoadjuvant chemotherapy (NAC) is unknown. Our study aimed evaluate clinical value of presence dynamic change treated NAC.Fifty-two early who underwent NAC were prospectively enrolled. Serial plasma samples...
Abstract Regulating innate immunity is an emerging approach to improve cancer immunotherapy. Such regulation requires engaging myeloid cells by delivering immunomodulatory compounds hematopoietic organs, including the spleen. Here we present a polymersome-based nanocarrier with splenic avidity and propensity for red pulp cell uptake. We characterized in vivo behaviour of four chemically identical yet topologically different polymersomes positron emission tomography imaging innovative flow...
Abstract Ensuring precise drug release at target sites is crucial for effective treatment. Here, pH‐responsive nanoparticles oral administration of mycophenolate mofetil, an alternative therapy patients with inflammatory bowel disease unresponsive to conventional treatments developed. However, its presents challenges due low solubility in the small intestine and high absorption stomach. Therefore, this aim design a delivery system capable maintaining compared free while delaying from stomach...
The luminescence properties of Ce3+,Na+-codoped MSi2O2−δN2+2/3δ (M = Ca, Sr, Ba) are reported. undoped and powders were prepared by a solid-state reaction at temperatures between 1300–1400 °C under N2–H2 (10%) atmosphere in the system MO–SiO2–Si3N4 Ba). crystallizes monoclinic with different crystal structures. For excitation 300–360 nm range, MSi2O2−δN2+2/3δ:Ce3+ shows typical broad emission bands peaking about 392, 473 396 for M Sr Ba, respectively. In particular, CaSi2O2−δN2+2/3δ:Ce3+ an...
Zika virus (ZIKV) is a reemerging flavivirus causing an ongoing pandemic and public health emergency worldwide. We developed nanoparticle-enhanced sensing of lysate for electrical detection ZIKV on paper microchip.
Bacterial cellulose (BC) and its bacterial producers have been employed in valuable applications the biomaterial, biomedicine food industries. In this study, three novel strains were isolated from traditional rice vinegar confirmed to be capable of producing BC, among which Acetobacter pasteurianus MGC-N8819 exhibited a relative high BC yield 6.6 g/L Hestrin-Schramm (HS) medium. Furthermore, agricultural lotus rhizome byproducts investigated as an alternative source for synthesis by strain....
Functionalized polymer vesicles have been proven to be highly promising in biomedical applications due their good biocompatibility, easy processability, and multifunctional responsive capacities. However, photothermal-responsive triggered by near-infrared (NIR) light not widely reported until now. Herein, we propose a new strategy for designing NIR light-mediated photothermal vesicles. A small molecule (PTA) with NIR-triggered features was synthesized combining D-D′-A-D′-D configuration...