Kamlesh Kumar Harsh

ORCID: 0000-0003-0424-0258
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About
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Research Areas
  • Head and Neck Cancer Studies
  • Advanced Radiotherapy Techniques
  • Endometrial and Cervical Cancer Treatments
  • Colorectal and Anal Carcinomas
  • Cervical Cancer and HPV Research
  • Cancer Treatment and Pharmacology
  • Head and Neck Surgical Oncology
  • Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Cancer Risks and Factors
  • Cancer survivorship and care
  • Effects of Radiation Exposure
  • Lung Cancer Research Studies
  • Liver Disease Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Oral health in cancer treatment
  • Radiation Therapy and Dosimetry
  • Management of metastatic bone disease
  • Esophageal and GI Pathology
  • Ovarian cancer diagnosis and treatment
  • Biosimilars and Bioanalytical Methods
  • Sarcoma Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer and Skin Lesions
  • Colorectal Cancer Screening and Detection

Sardar Patel Medical College
2015-2024

Creative Commons
2018-2023

Sarojini Naidu Medical College
2023

Government Medical College
2018

Introduction: Advancements in radiation oncology improve the outlook for patients with head and neck cancer which allowed to escalate dose of tumours while minimizing surrounding healthy tissues. This study aims comparison radiotherapy treatment planning 3 DCRT VMAT cancer.Methods: Prospective conducted on fifty 25 were treated VMAT. Both plans evaluated compare efficiency dosimetrically terms PTV volume, homogeneity index, conformity index doses organs at risk. Results: Dose D98% PTV66 was...

10.31557/apjcc.2024.9.1.49-53 article EN cc-by Asian Pacific Journal of Cancer Care 2024-02-10

Chronic rhino-sinusitis (CRS) is a significant health problem whose incidence and prevalence rising. An emphasis has been placed on diseasespecific quality of life (QoL as the predominant measure for most current outcome studies. Therefore validated health-related QoL in sinonasal disease needed. The present prospective observational study was conducted 50 patients Department ENT at Govt. Medical College Rajindra Hospital Patiala, Punjab, India. primary outcomes were following: (1) chance...

10.4103/njcp.njcp_429_17 article EN Nigerian Journal of Clinical Practice 2018-01-01

Ovarian cancer is a leading cause of death from gynecological in the world and India. This study aims to evaluate efficacy toxicity profile oral metronomic chemotherapy (MCT) form etoposide, cyclophosphamide, tamoxifen recurrent metastatic ovarian cancer.

10.4103/ijc.ijc_143_20 article EN PubMed 2023-08-02

Head-and-neck cancer is the most common in developing countries of Southeast Asia. Most patients present to hospital advanced stage and have a poor prognosis. This study aims evaluate efficacy toxicity profile oral metronomic chemotherapy (MCT) form methotrexate celecoxib locally advanced, recurrent metastatic head-and-neck cancers.This was single-arm retrospective observational that included posttreatment with disease year 2016 (January 1, December 31, 2016). A total 84 warranting...

10.4103/jcrt.jcrt_702_18 article EN Journal of Cancer Research and Therapeutics 2020-01-01

Ranjith K.The objective of this study was to compare the efficacy, safety, pharmacokinetics, and immunogenicity a proposed bevacizumab biosimilar (DRL_BZ) with innovator Avastin (reference medicinal product [RMP]) in patients nonresectable metastatic colorectal cancer (mCRC) over period 9 months advanced nonsquamous non-small cell lung (NSCLC) 6 months. The planned as randomized, double-blind trial. In part A, total 117 mCRC were intended receive 5 mg/kg every 2 weeks along mFOLFOX6...

10.1055/s-0043-1774403 article EN cc-by-nc-nd South Asian Journal of Cancer 2023-10-13

The benefit of definitive chemoradiotherapy (CRT) in elderly patients with locally advanced esophageal cancer is not well established. We perform a single institutional retrospective study CRT terms toxicity (age more than 60 years) as compared young cohort <60 nonmetastatic cancer.A total 145 patients, 79 age (Group A) and 66 elder B) Stage II III squamous cell carcinoma the esophagus ECOG PS 0-1, who had undergone at our institute from January 2015 to November 2018 were selected for this...

10.4103/jcrt.jcrt_878_18 article EN Journal of Cancer Research and Therapeutics 2020-01-01

Background: Overall, the incidence of colorectal cancer appears to be stable or diminishing.However, based on our regional institute's datas, we have observed increasing in patients ≤40 age.The aim this study was verify rising trend, clinico-pathological features and survival ≤40,in comparison >40 age. Materials methods:A retrospective conducted review all patients≤ 40 age more than year separatly with a diagnosis from January 2004 December 2012.Results: Young were 24.17% total 1096 cases.In...

10.9790/0853-1601040105 article EN IOSR Journal of Dental and Medical Sciences 2017-01-01

Purpose: Linear-Quadratic (LQ) model has been widely used for describing radiobiological effectiveness of various fractionation schedules on tumour as well normal tissues. This study estimates α/β acute tissue reactions using Fe-plot method. Methods: 50 cases locally advanced head and neck squamous cell carcinoma (stage III IV) treated with external beam radiotherapy were included in this study. Patients randomly distributed into Hyper-fractionation (HF) arm (1.2 Gy/fraction, twice daily, 6...

10.14319/ijcto.44.9 article EN International Journal of Cancer Therapy and Oncology 2016-12-28

Purpose: The purpose of this study was to compare treatment response and toxicity profile among two groups unresectable locally advanced head neck malignancies receiving concurrent chemo-radiotherapy versus radiotherapy alone after completing neoadjuvant chemotherapy. Material methods: Total 50 patients received chemotherapy (inj. paclitaxel 175 mg/m2 D1, Cisplatin 80mg/m2 divided in 2 days &amp; inj 5FU 1gm/m2 iv d1&amp;d2). Then randomly allotted into above receive 66 Gy fractionated RT...

10.31557/apjcc.2024.9.3.443-446 article EN cc-by Asian Pacific Journal of Cancer Care 2024-07-20

The American Brachytherapy (BT) Society recommends that BT must be included as a component of the definitive radiation therapy for cervical carcinoma because recurrences and complications are decreased when is used in addition to external beam radiotherapy. aim this study quantify interfraction dose variations (VARacts) during high rate (HDR) BT, effect variation terms excess "unrecognized" OAR conclude reason reference applicator position/geometry versus deformation organ at risk (OAR)...

10.4103/jcrt.jcrt_797_21 article EN Journal of Cancer Research and Therapeutics 2023-07-01

&#x0D; Aim: The purpose of this study is to evaluate the late toxicities in hypo fractionated radiation schedule breast cancer patients with regional nodal irradiation (RNI), limited axilla and supraclavicular regions. Late effects on arm shoulder were noted as follows: skin edema (lymphedema), restricted movements (brachial plexus injury) localised pain.Material Methods: In we randomly enrolled 100 post mastectomy cases year 2018. All previously asymptomatic after surgery. They...

10.31557/apjcc.2021.6.3.311-315 article EN cc-by Asian Pacific Journal of Cancer Care 2021-08-27
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