Copper nanoparticles used as a dietary supplement for poultry could affect the absorption of mineral elements. Hence aim study was to determine effect administration copper chickens in drinking water on intestinal iron, zinc, and calcium. The experiment carried out 126 chicks assigned seven experimental groups 18 birds each (3 replications 6 individuals each). control group (G-C) did not receive nanoparticles. Groups: Cu-5(7), Cu-10(7), Cu-15(7) received gold their amounts 5 mg/L 10 15...

Abstract The aim of this experiment was to determine what dosage copper (Cu) nanoparticles, added a standard dietary supplementation with sulfate, would improve antioxidant and immune defense in chickens. conducted 126 broiler chickens assigned seven treatments three pens per treatment six pen. basal‐diet did not receive Cu nanoparticles (nano‐Cu) as shown by analyses it Cu‐deficient (−29% vs. National Research Council ( NRC) recommendations; 5.7 8 mg/kg). Broiler received nano‐Cu (0.5, 1.0...

The aim of the study was to investigate effect two forms (CuCO3 (CuS); and Cu nanoparticles (CuNP)) dosages (standard 6.5 mg/kg (H), half standard (L)) additional dietary administered growing rats on gastrointestinal hepatic function morphology. Copper in form CuNP vs CuS caused lower faecal/urinal excretion increased accumulation brain tissue. Hepatic high-grade hydropic degeneration necrotic lesions were observed only CuNP-H animals. In gut, application stifled bacterial enzymatic activity...

Due to exposure of animals numerous stress-inducing factors and a high level cellular metabolism resulting from the conditions manner in which they are raised, destabilisation redox balance towards excessive activity free radical species is common phenomenon. Enhancing antioxidant status animal organism by optimising quality feeding, especially supplementation with exogenous antioxidants, may be one essential highly effective means improving health thus productivity animals. Natural plant...

The aim of the study was to analyze how per os application hydrocolloids silver nanoparticles (22 nm) and lipid-coated (5 affect immune, redox, lipid status blood broiler chickens. experiment conducted on 60 first group control (Group C). chickens in Group II received a nanoparticle hydrocolloid (Ag-nano) at dose 5 mg/kg body weight (BW) day. III (AgL-nano) BW Blood for analysis collected from 24- 38-day-old several parameters were determined. increase phagocytosis metabolic activity...

Introduction The study aimed to determine the effect of manganese (Mn) exclusion from mineral mixture added rat diet and replacing recommended level MnCO 3 (65 mg Mn/kg diet) with Mn 2 O nanoparticles (Mn NPs) in on blood hematology selected immunological indices blood, jejunum, brain. Methods experiment was conducted twenty-four, Wistar rats divided into equal groups. control (K) group received a containing 65 mg/kg additional originating mixture), B (negative control) fed deprived mixture,...

Abstract The aim of the study was to analyse how per os application hydrocolloids silver nanoparticles (22 nm) and lipid-coated nanosilver (5 affect microbiological status morphology jejunum broiler chickens their growth performance. experiment conducted on 60 chickens. first group control. in II received a nanoparticle hydrocolloid (Ag-nano) at dose 5 mg/kg b.w./day. III (AgL-nano) Samples digesta were taken from during dissection total numbers fungi, aerobic bacteria coli determined...

The aim of the study was to determine how a high-fat diet supplemented with various forms chromium affects hematological and immune parameters blood rats. rats received standard or at 0.3 mg/kg body weight (BW) in form chromium(III) picolinate, chromium(III)-methionine nano-sized chromium. Selected were determined rats, including total white cell (WBC) count, leukogram, red (RBC) hemoglobin level (HGB), hematocrit (HCT), platelet count (PLT) percentage (PCT), as well parameters: levels...

The study on Wistar rats was conducted to investigate the effects of a pharmacologically relevant dose 0.3 mg/kg body weight chromium supplementation (commonly used picolinate or novel form as nanoparticles) and switching away from obesogenic dietary habits parameters lipid metabolism, inflammation, oxidative stress in liver plasma. Favorable related changes diet were considerably enhanced when supplemented with nanoparticles. This combination exerted strongest fat content cholesterol...

Abstract The aim of the study was to evaluate effects a diet containing different levels Cu in two chemical forms (carbonate and nanoparticles) on redox reactions epigenetic changes rat model. For 4 weeks, five experimental groups (eight rats each) were fed diets with dosages added (standard—6.5 mg/kg or half standard dosage—3.25 mg/kg, as negative control no additional mineral mixture) (standard—CuCO 3 copper nanoparticles). Addition nanoparticles resulted higher Cp (ceruloplasmin) activity...

Schizophrenia is a severe and chronic mental illness usually diagnosed in adolescents young adults. Many studies indicate that oxidative stress causes membrane dysfunction cell damage, which implicated the pathophysiology of schizophrenia. The purpose our study was to evaluate markers (the main primary products lipid peroxidation, hydroperoxides (LOOH), end malondialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH), Ferric Reducing Ability Plasma (FRAP)) plasma patients with first...

The aim of the study was to investigate effect returning a balanced diet combined with chromium picolinate (CrPic) or nanoparticles (CrNPs) supplementation at pharmacologically relevant dose 0.3 mg/kg body weight on expression level selected genes and bone turnover markers in blood bones rats fed an obese diet. results showed that chronic intake high-fat obesogenic negatively affects by impairing processes both synthesis degradation bones. switch healthy proved insufficient regulate...

Abstract The aim of the study was to determine effect recommended (6.5 mg/kg) or enhanced (13 level CuNPs in diet combination with different types dietary fibre – cellulose (control), inulin, pectin, psyllium on Cu biodistribution and selected minerals parameters blood rats. Rats were randomly divided into 10 groups. first two groups fed control diets containing a mineral mixture standard content CuCO 3 . Experimental supplemented 13 combined (cellulose, psyllium). After feeding period...

The aim of the study was to verify hypothesis regarding effect recommended (6.5 mg/kg) or enhanced (13 level CuNPs in diet combination with different types dietary fibre-cellulose (control), inulin, pectin psyllium-on selected biological parameters intestinal integrity rats. Rats were randomly divided into 10 groups. first two groups fed a control that contained cellulose, and mineral mixture standard content CuCO3. Experimental supplemented 13 combined fibre (cellulose, pectin, inulin...

The aim of this experiment was to test the effect partial or complete replacement traditional CuCO3 in diet rats with copper nanoparticles (CuNPs) on biochemical parameters, redox status, and histomorphometry their tissues. Normotensive male Wistar–Kyoto (WKY) were allocated three groups. Three analogous groups spontaneously hypertensive (SHR) also formed. WKY SHR received a standard daily dose—6.5 mg/kg CuNPs (100% replacement) 3.25 plus (50% replacement)—for 8 weeks. Next, blood, heart,...

The amount of berry polyphenols required to exert health-promoting effects seems be difficult achieve by fresh fruit ingestion, so polyphenol-rich extracts could considered a dietary alternative. In the present study, laboratory rats were fed high-fat diets supplemented with 0.1 or 0.3% raspberry from pomace, former dose reflecting consumed glass raspberries. It was hypothesized that beneficial changes in blood and hepatic tissue related lipid metabolism would accompany both treatments, but...

It was assumed that early administration of enrofloxacin or doxycycline may impair immune function and alter the morphology organs system in turkeys, diets containing coccidiostat monensin, an ionophore antibiotic, can exert similar effects. The aim this study to determine whether antibiotic feeding a diet affect young turkeys. experiment had completely randomized design, with eight groups (a total 3080 one-day-old turkeys), seven replicate pens per group 55 birds pen. two-factorial four...

Abstract It was postulated that administration of a probiotic to chickens can stimulate their antioxidant status while at the same time inhibiting oxidation processes. The objective study determine whether and how different levels durations application preparation containing live cultures Enterococcus faecium enriched with cholecalciferol ascorbic acid influences indicators lipid redox reaction in blood broiler chickens. Four hundred day-old Ross 308 were raised until 42nd day age. animals...

Abstract It was postulated that naturally occurring phenolic compounds obtained from various plant species may have potential use as feed additives for poultry. Therefore the aim of study to compare extracts hesperidin, diosmin, quercetin and resveratrol in terms their health-promoting (particularly immunostimulatory) effect on turkeys at different ages. The experiment conducted 720 Big 6 turkey hens assigned experimental groups 120 individuals (6 repetitions with 20 birds each). group G-C...

The aim of the study was to determine how feeding rats a high-fat diet supplemented with various forms chromium affects DNA methylation and oxidation reactions as well histology heart brain tissue. received standard or at 0.3 mg/kg body weight (BW) in form (III) picolinate, (III)-methionine, nano-sized chromium. content malondialdehyde (MDA), protein carbonyl (PC), 8-hydroxydeoxyguanosine (8-OHDG), level global activity selected repair enzymes were determined blood. In heart, MDA, PC,...

Previous studies showed that chromium nanoparticles (Cr-NPs) might be used as dietary compounds against some obesity-related disorders; however, there is little information on how these influence the gut microenvironment. The aim of this study was to investigate whether negative effects a high-fat diet in large intestine rats mitigated by switching low-fat and supplementation with Cr-NPs. Microbiota sequencing analysis revealed main action Cr-NPs focused changing microbiota's activity....

We aimed to analyze how supplementation with a standard (recommended, 6.5 mg/kg) or enhanced (two-times higher, 13 dose of copper (Cu), in the form nanoparticles (NPs) along dietary intervention via implementation diverse types fiber, affects cardiovascular system rats. Nine-week-old male Wistar Han rats (n/group = 10) received, for an additional 6 weeks, controlled diet cellulose as fiber and ionic Cu (in carbonate salt). The experimental groups received cellulose, pectin, inulin, psyllium...

The present study assessed the changes in faecal microbial activity obese Wistar rats fed high-fat or low-fat diets supplemented with various forms of chromium (picolinate nanoparticles). 18-week was divided into two phases: an introductory period (9 weeks; obesity status induction via a diet) and experimental maintained on diet switched to Cr supplementation). During (10–18 weeks feeding), samples fresh faeces were collected chosen days. bacterial enzymatic short-chain fatty acids (SCFAs)...