A5080772941- Pancreatic and Hepatic Oncology Research
- Esophageal Cancer Research and Treatment
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Cancer Genomics and Diagnostics
- Neuroendocrine Tumor Research Advances
- Radiomics and Machine Learning in Medical Imaging
- Tracheal and airway disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Medical Imaging and Pathology Studies
- Family Support in Illness
- Cancer Research and Treatments
- Organ Transplantation Techniques and Outcomes
- Cardiovascular Effects of Exercise
- Immune Cell Function and Interaction
- Cancer survivorship and care
- Ion channel regulation and function
- Renal Transplantation Outcomes and Treatments
- Genetics and Physical Performance
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Semantic Web and Ontologies
University of Pittsburgh
2019-2024
The Ohio State University Wexner Medical Center
2008-2019
The Ohio State University
2008-2019
VA Pittsburgh Healthcare System
2019
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2012-2015
City Of Hope National Medical Center
2012
Scripps Green Hospital
2012
City of Hope
2012
Ohio University
1996-2008
Canadian Pacific Railway (Canada)
2003
<b>Background and aims:</b> Endoscopic ultrasound (EUS)-guided needle-based Confocal Laser Endomicroscopy (nCLE) characteristics of pancreatic cystic lesions (PCLs) have been identified in studies where the gold standard surgical histopathology was available a minority patients. There are diverging reports interobserver agreement (IOA) paucity intraobserver reliability (IOR). Thus, we sought to validate current EUS-nCLE criteria PCLs larger consecutive series <b>Methods:</b> A retrospective...
Our objective was to delineate predictive factors differentiating groove pancreatitis (GP) from other lesions involving the head of pancreas (HOP).A case-control study patients older than 10 years performed comparing with GP those surgically resected HOP lesions.Thirteen (mean ± SD age, 51.9 10.5 years; 11 males [84.6%]), all a history smoking (mean, 37.54 17.8 pack-years), were identified. Twelve (92.3%) had heavy alcohol drinking (heavy [EtOH]). The mean lesion size 2.6 1.1 cm, and CA 19-9...
275 Background: FOLFIRINOX exhibits a meaningful improvement in outcome measures metastatic pancreatic cancer, making it an interesting regimen for BRPC and LAURPC. However, its use remains prohibitive due to toxicity. In this study, we examine the outcomes of mFOLFIRINOX as neoadjuvant strategy patients with Methods: This is retrospective analysis prospectively maintained database who received or LAURPC at Ohio State University. follows: irinotecan 165 mg/m 2 ; oxaliplatin 85 5-fluorouracil...
Solid pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor presenting in adolescent and young adult females. A previously healthy 13 year-old female presented to our institution with abdominal pain emesis. Imaging revealed pancreatic cystic mass. Endoscopic ultrasound (EUS) fine needle biopsy suggested SPN. Pathologic evaluation following resection immunohistochemical (IHC) staining positive for β-catenin α-1-antitrypsin despite extensive necrosis. We discuss this patient as well...
Blockade of the vascular endothelial growth factor (VEGF) pathway shows evidence activity in gastro-oesophageal (GE) and oesophageal cancer. We investigated efficacy sunitinib, a multikinase VEGF inhibitor, patients with relapsed/refractory GE/oesophageal This was single-stage Fleming phase II study. The primary end point progression-free survival (PFS) at 24 weeks. If five or more out total 25 were free progressive disease weeks, sunitinib would be recommended for further Patients received...
Pancreatic adenocarcinoma is an aggressive disease that has poor outcomes despite maximal traditional therapies. Thus, treatment of this cancer demands innovative strategies to be used in addition standing therapies order provide new avenues care. Here, we describe the technique using endoscopic ultrasound directly inject both novel and conventional into pancreatic tumors. We detail rationale behind strategy many benefits it provides. then our detail, including experience injecting AdV-tk...
As novel acute allograft rejection mechanisms are being discovered, determining the conditions that promote or subvert these distinct pathways is important to interpret clinical relevance of for specific recipient groups as well tissue and organ transplants. We have employed a versatile hepatocellular model analyze how host immune repertoire locale influences phenotype pathway. In addition, we investigated peripheral monitoring cellular humoral parameters correlates with activity Complete...
The aim of this study is to determine the diagnostic accuracy preoperative evaluation detect main pancreatic duct involvement in cystic lesions thus differentiating mixed intraductal papillary mucinous neoplasm (IPMN) from branch (BD)-IPMN.The pathology database resections 2000 2014 was reviewed. Main duct-IPMNs and IPMNs with intracystic mass/nodules were excluded. test characteristics analyzed using surgical histopathology as "gold standard."Sixty BD-IPMNs 23 mixed-IPMNs identified....