A5001833667- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Blood donation and transfusion practices
- Extracellular vesicles in disease
- Hemoglobinopathies and Related Disorders
- HIV, Drug Use, Sexual Risk
- Platelet Disorders and Treatments
- MicroRNA in disease regulation
- COVID-19 Clinical Research Studies
- Blood transfusion and management
- Blood properties and coagulation
- Blood groups and transfusion
- SARS-CoV-2 and COVID-19 Research
- Health and Well-being Studies
- COVID-19 epidemiological studies
- Animal Disease Management and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- RNA Interference and Gene Delivery
- T-cell and Retrovirus Studies
- Iron Metabolism and Disorders
- Viral-associated cancers and disorders
- Healthcare and Environmental Waste Management
- Liver Disease and Transplantation
- Microbial Inactivation Methods
High Institute for Education and Research in Transfusion Medicine
2016-2025
Iranian Legal Medicine Organization
2005-2023
Baqiyatallah University of Medical Sciences
2012
Imam Khomeini Hospital
2012
Hospital Universitario Son Dureta
2002
Hôpital Cochin
2001
Withington Community Hospital
1998
ObjectiveEarly studies on blood donors point to a seroprevalence of approximately 0.25% for hepatitis C virus (HCV) infection in Iran. However, the true prevalence general population is unknown. The objective this study was determine HCV Iran.MethodsWe randomly selected 6583 subjects from three provinces Iran inclusion study. Subjects were aged between 18 and 65 years. Anti-hepatitis antibody tested by third-generation ELISA test. A recombinant immunoblot assay (RIBA) test used confirm...
Evaluation and monitoring the prevalence of transfusion-transmissible viral infections in blood donors is a valuable index donor selection safety. This study analyzed trends blood-borne among Iranian donations during 4 years.Viral screening results 6,499,851 allogeneic from 2004 through 2007 were analyzed. All screened for hepatitis B virus (HBV), C (HCV), human immunodeficiency (HIV), syphilis. The HBV, HCV, HIV per 100,000 95% confidence interval was calculated. p value estimated by...
Background: Blood donor selection is a crucial stage in reducing the risk of transfusion-transmissible infections (TTIs) and ensuring safety blood components. The objective this study to evaluate impact each question regarding deferral reasons on TTIs. Methods: This was conducted twenty transfusion centers between March 1, 2018, September 30, 2019, including high-risk deferred volunteers from seven different groups. All samples were screened for HBsAg, anti-HCV, HIVAg/Ab. Negative pooled...
summary . Assessment of the quality donor selection and safety blood supply can be estimated by monitoring prevalence serologic markers infectious disease in screening tests. In present study, changes rates hepatitis B virus (HBV) infection are studied period 1998–2007 Iranian Blood Transfusion Organization (IBTO). Prevalence serological marker HBV [hepatitis surface antigen (HBsAg)] was evaluated donations Iran as well for Fars province representing a low prevalence, Sistan‐Baluchestan...
Microvesicles are released by different cell types and shuttle mRNAs microRNAs which have the possibility to transfer genetic information a target alter its function. Acute myeloid leukemia is malignant disorder, leukemic cells occupy all bone marrow microenvironment. In this study, we investigate effect of microvesicles on healthy umbilical cord blood hematopoietic stem find evidence transferring. Leukemia were isolated from acute patients co-incubated with cells. After 7 days, count,...
Treatment guidelines contraindicate ribavirin for treatment of hepatitis C virus (HCV) infection in thalassemia major patients. Nevertheless, the current evidence suggests that might be tolerated by these patients.Despite this evidence, low dose combination therapy has not been compared with peginterferon monotherapy patients so far.Two hundred eighty detectable HCV-RNA PCR (≥ 50 IU/mL) and liver histology consistent chronic HCV were self-assigned to receive alfa-2a (n = 81) or its...
COVID-19 first appeared in Iran on 19 February 2020, and then spread rapidly over the country. In this article, we review action plan of Iranian Blood Transfusion Organization with respect to disease.We collected data blood donations RBC inventory for 8 weeks outbreak. We also evaluated trend compared them past year. include a summary actions taken by National Committee Management outbreak.Blood decreased from 33 275 23 465 units during 2 outbreak corresponding decrease inventory. But after...
Background: hepatitis B virus (HBV) infection is a major public health problem that affects billions of people worldwide. The lack information on HBV prevalence among the general population an obstacle to formulate effective policies reduce burden viral hepatitis. Objectives: This based serological survey was conducted in Kermanshah province determine local and risk factors infection. Patients Methods: 1979 healthy subjects were selected from all districts (in west Iran) using random cluster...
Microvesicles can transfer their contents, proteins and RNA, to target cells thereby transform them. This may induce apoptosis or survival depending on cell origin the cell. In this study, we investigate effect of leukemic microvesicles umbilical cord blood hematopoietic stem seek evidence survival. were isolated from both healthy donor bone marrow samples Jurkat by ultra-centrifugation added sorted magnetic associated sorting (MACS) technique. After 7 days, count, viability, flow cytometry...