Lisa Whisker
A5047909909- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Breast Cancer Treatment Studies
- COVID-19 and healthcare impacts
- Breast Lesions and Carcinomas
- Reconstructive Facial Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Cancer Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Body Contouring and Surgery
- Advances in Oncology and Radiotherapy
- Digital Imaging in Medicine
- BRCA gene mutations in cancer
- Cancer Treatment and Pharmacology
- Cancer and Skin Lesions
- Trauma and Emergency Care Studies
- Clinical practice guidelines implementation
- Innovations in Medical Education
- Salivary Gland Tumors Diagnosis and Treatment
- Diversity and Career in Medicine
- Surgical Sutures and Adhesives
- Advanced Breast Cancer Therapies
- Health and Medical Research Impacts
Nottingham University Hospitals NHS Trust
2015-2024
Worcestershire Acute Hospitals NHS Trust
2010-2024
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2020-2022
Breast Center
2021-2022
University of Edinburgh
2022
NIHR Bristol Biomedical Research Centre
2022
North Bristol NHS Trust
2022
Southmead Hospital
2022
Nottingham City Hospital
2013-2022
University of Birmingham
2020-2021
BackgroundUse of biological or synthetic mesh might improve outcomes immediate implant-based breast reconstruction—breast reconstruction with implants expanders at the time mastectomy—but there is a lack high-quality evidence to support safety effectiveness technique. We aimed establish short-term performed and without mesh, inform feasibility undertaking future randomised clinical trial comparing different techniques.MethodsIn this prospective, multicentre cohort study, we consecutively...
Abstract Introduction Prepectoral techniques are becoming standard of care for implant-based breast reconstruction due to reduced impact on chest wall function and improved patient satisfaction. Evidence support these benefits, however, is lacking. Here, patient-reported outcomes (PROs) prepectoral (PPBR) in the Pre-BRA cohort reported. Methods Women undergoing PPBR after mastectomy cancer or risk reduction between July 2019 December 2020 were recruited. Participants completed BREAST-Q...
Ensuring that doctors in training acquire sufficient knowledge, experience and understanding of medical research is a universal longstanding issue which has been brought into sharper focus by the growth evidence based medicine. All healthcare systems preparing for practice have to balance acquisition specific clinical attitudes, knowledge skills with wider need ensure are equipped remain professionally competent as science advances. Most professional bodies acknowledge this requires trainee...
Abstract Background Therapeutic mammaplasty (TM) may be an alternative to mastectomy, but few well designed studies have evaluated the success of this approach or compared short-term outcomes TM with mastectomy without immediate breast reconstruction (IBR). Data from national iBRA-2 and TeaM were combined compare safety IBR. Methods The subgroup patients in study who underwent avoid identified, data on demographics, complications, oncology adjuvant treatment those undergoing IBR study....
Abstract Background Therapeutic mammaplasty, which combines breast reduction and mastopexy techniques with tumour excision, may extend the boundaries of breast-conserving surgery improve outcomes for patients, but current practice is unknown high-quality outcome data are lacking. This prospective multicentre cohort study aimed to explore short-term technique. Methods Consecutive patients undergoing therapeutic mammaplasty at participating centres between 1 September 2016 30 June 2017 were...
The introduction of biological and synthetic meshes has revolutionised the practice implant-based breast reconstruction (IBBR) but evidence for effectiveness is lacking. iBRA (implant Breast Reconstruction evAluation) study a national trainee-led project that aims to explore outcomes IBBR inform design future trial. We report results National Practice Questionnaire (NPQ) which aimed comprehensively describe provision across UK. A questionnaire investigating local service developed by...
Abstract Background Biological and synthetic meshes may improve the outcomes of immediate implant-based breast reconstruction (IBBR) by facilitating single-stage procedures improving cosmesis. Supporting evidence is, however, limited. The aim this study was to explore impact biological mesh on patient-reported (PROs) IBBR 18 months after surgery. Methods Consecutive women undergoing between February 2014 June 2016 were recruited study. Demographic, operative, oncological 3-month complication...
Abstract Background Oncoplastic breast-conserving surgery may allow women with early breast cancer to avoid a mastectomy, but many undergo more extensive surgery, even when options are offered. The aim of the ANTHEM qualitative study was explore factors influencing women’s surgical decision-making for and against oncoplastic surgery. Methods Semi-structured interviews were conducted purposive sample who had received either or mastectomy without immediate reconstruction their rationale...
Abstract Background Oncoplastic breast-conserving surgery may be a better option than mastectomy, but high-quality comparative evidence is lacking. The aim of the ANTHEM study (ISRCTN18238549) was to explore clinical and patient-reported outcomes in multicentre cohort women offered oncoplastic as an alternative mastectomy with or without immediate breast reconstruction. Methods Women invasive/pre-invasive cancer who were volume replacement displacement techniques avoid recruited...
Implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure in UK. The introduction of techniques to augment subpectoral pocket has revolutionised procedure, but there a lack high-quality outcome data describe safety or effectiveness these techniques. Randomised controlled trials (RCTs) are best way comparing treatments, surgical RCTs challenging. iBRA (implant evaluation) study aims determine feasibility, design and conduct pragmatic RCT examine...
Abstract Background Immediate implant-based breast reconstruction (IBBR) is the most commonly performed reconstructive procedure in UK, but almost one ten women experience implant loss and failure after this technique. Little known about how impacts on patients' quality of life. The first phase Loss Breast Reconstruction (LiBRA) study aimed to use qualitative methods explore women's experiences develop recommendations improve care. Methods Semistructured interviews were conducted with a...
Abstract Background Breast angiosarcomas are rare tumours of vascular origin. Secondary angiosarcoma occurs following radiotherapy for breast cancer. Angiosarcomas have high recurrence and poor survival rates. This is concerning owing to the increasing use adjuvant treatment invasive cancer ductal in situ (DCIS), which could explain rising incidence angiosarcoma. Outcome data limited provide a evidence base treatment. paper presents national, trainee-led, retrospective, multicentre study...
IntroductionThe 2008 National Mastectomy and Breast Reconstruction Audit demonstrated marked variation in the practice outcomes of breast reconstruction UK. To standardise improve for patients, British professional associations developed best-practice guidelines with specific guidance newer mesh-assisted implant-based techniques. We explored degree uptake within units performing (IBBR) as first phase implant Evaluation (iBRA) study.MethodsA questionnaire by iBRA Steering Group was completed...
A recent Association of Breast Surgery summary statement on fibroadenoma management recommends excision only for cellular fibroepithelial lesions and rapidly growing with a core biopsy diagnosis fibroadenoma; persistent pain is relative indication excision.This retrospective study looked at the impact this approach would have phyllodes tumours.From 2014 to 2018, there were 1,058 diagnoses 112 excised, which 98 fibroadenomas, 4 hamartomas 10 tumours. In group, an tumour was associated size...
Prepectoral breast reconstruction (PPBR) has recently been introduced to reduce postoperative pain and improve cosmetic outcomes in women having implant-based procedures. High-quality evidence support the practice of PPBR, however, is lacking. Pre-BRA an IDEAL stage 2a/2b study that aimed establish safety, effectiveness, stability PPBR before definitive evaluation RCT. The short-term safety endpoints at 3 months after surgery are reported here.Consecutive patients electing undergo immediate...
Abstract Purpose Up to 40% of the 56,000 women diagnosed with breast cancer each year in UK undergo mastectomy. Seroma formation following surgery is common, may delay wound healing, and be uncomfortable or start adjuvant treatment. Multiple strategies reduce seroma include surgical drains, flap fixation external compression exist but evidence support best practice lacking. We aimed survey surgeons determine current inform feasibility undertaking a future trial. Methods An online was...
David Bartlett and colleagues explain why joining a research collaborative can help your career
Outcome reporting in research studies of breast reconstruction is inconsistent and lacks standardisation. The results individual therefore cannot be meaningfully compared or combined limiting their value. A core outcome set (COS) has been developed to address these issues identified 11 key outcomes measured reported all future audit reconstructive surgery (RBS). COS represents what should measured. next step determine how when this done. aim study develop a measurement (CMS) for use...
To explore the impact of PMRT on PROs IBBR performed with and without mesh.