A5043619925- Advancements in Transdermal Drug Delivery
- Endodontics and Root Canal Treatments
- Osteoarthritis Treatment and Mechanisms
- Proteoglycans and glycosaminoglycans research
- Advanced Drug Delivery Systems
- Laser Applications in Dentistry and Medicine
- Drug Solubulity and Delivery Systems
- Dental Anxiety and Anesthesia Techniques
- Essential Oils and Antimicrobial Activity
- Medical and Biological Ozone Research
- Skin Protection and Aging
- Antimicrobial Peptides and Activities
- Nanoplatforms for cancer theranostics
- Inflammatory mediators and NSAID effects
- Glaucoma and retinal disorders
- thermodynamics and calorimetric analyses
- Plant-based Medicinal Research
- Analytical Methods in Pharmaceuticals
Misr University for Science and Technology
2019-2024
Abstract The majority of conventional osteoarthritis (OA) treatments are based on molecular adjustment certain signaling pathways associated with pathogenesis, however there is a significant need to search for more effective and safe treatments. This study centers around formulating Aceclofenac (ACF) high bioavailability in combination Citronellol oil collagen. optimal concentrations oil/D-Limonene oil, Tween 80, Transcutol HP were determined using pseudoternary phase diagram. formulated...
Introduction and aim: Chlorhexidine Hydrochloride [Chx.HCl] has a broad-spectrum antibacterial effect, sustained action low toxicity so it been recommended as potential root canal irrigant. The aim of this study was to improve the penetration ability, cleansing effect Chx.HCl using newly formulated nanoemulsion use Methods: nanoemulsions were prepared two different oils; Oleic acid Labrafil M1944CS, surfactants; Tween 20 80 co-surfactant; Propylene Glycol. Pseudoternary phase diagrams...
This study aims at preparing propranolol-loaded trehalosomes (a trehalose-coated liposome) to be used as an antiproliferative agent for treating skin cancer. A factorial design was select the optimum formula, where trehalose, lecithin, and Tween 80 levels were studied. total of 24 runs prepared characterized according size, charge, entrapment efficiency, release after 3 h formula. The optimized formula investigated using TEM, DSC, FTIR. Cell studies carried out against human melanoma cell...
Enalapril (EN) is an antihypertensive drug that sparingly soluble in water with limited oral bioavailability. Successfully prepared self-nanoemulsifying systems (SNES) loaded EN were developed. The solubility of different oils, surfactants, and cosurfactants was tested. Pseudoternary phase diagrams developed, various SNES formulations evaluated regarding content uniformity, emulsification time, droplet size (DS), zeta potential (ZP). selected system examined using transmission electron...
Aceclofenac (ACF) is a widely used non-steroidal anti-inflammatory drug (NSAID) known for its effectiveness in treating pain and inflammation. Recent studies have demonstrated that ACF possesses antiproliferative properties, inhibiting the growth of cancer cells various cell lines. Citronellol, monoterpenoid alcohol found essential oils, exhibits antioxidant properties activities such as acetylcholinesterase inhibition. In this study, objective was to formulate evaluate an...
Introduction and Aim: Sodium hypochlorite (NaOCl) has proven to be the chosen irrigator in modern practice due its high tissue solution power, antibacterial, lubricant properties.This study aimed use a Lipid-Free Nanoemulsion (LF/NE) improve penetration efficiency, antibacterial effect, dissolving, cleansing ability of NaOCl.Moreover, masking NaOCl taste when used as root canal irrigant.Methods: LF/NE were comprised mixture surfactants (Tween20 Tween 80) cosolvents (Transcutol HP propylene...