A5027132270- Genomics and Phylogenetic Studies
- Single-cell and spatial transcriptomics
- Cell Image Analysis Techniques
- Immune cells in cancer
- Microbial Community Ecology and Physiology
- Cancer Genomics and Diagnostics
- Retinal Development and Disorders
- Genetic diversity and population structure
- Diverse Education Studies and Reforms
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Psychosocial Factors Impacting Youth
- Identification and Quantification in Food
- Mycobacterium research and diagnosis
- Developmental Biology and Gene Regulation
- Parental Involvement in Education
- Neurogenesis and neuroplasticity mechanisms
- Circular RNAs in diseases
- Pluripotent Stem Cells Research
- Aquaculture Nutrition and Growth
University of Hong Kong
2022-2024
Laboratory of Data Discovery for Health
2024
Chinese University of Hong Kong
2023
Hong Kong Science and Technology Parks Corporation
2023
Walter and Eliza Hall Institute of Medical Research
2016
The University of Melbourne
2015
Understanding the emergence of human notochordal cells (NC) is essential for development regenerative approaches. We present a comprehensive investigation into specification and generation
This study examines the experiences of five Kansan parents who took on a key role in their children’s home education during pandemic. The author uses online interviews to investigate how parental agency is manifested through parents’ actions regarding and health. Drawing inspiration from Bandura’s theory human agency, applies four core properties agency: intentionality, forethought, self-reactiveness, self-reflectiveness. discussion connects findings broader literature offering insights into...
MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that regulate gene expression by post-transcriptional repression mRNAs. Recently, several miRNAs have been confirmed to execute directly or indirectly osmoregulatory functions in fish via translational control. In order clarify whether play relevant roles the osmoregulation Anguilla marmorata, three sRNA libraries A. marmorata during adjusting various salinities were sequenced Illumina deep sequencing methods. Totally...
Reduced representation bisulfite sequencing (RRBS) provides an efficient method for measuring DNA methylation at single base resolution in regions of high CpG density. This technique has been extensively tested on the HiSeq2500, which uses a 4-colour detection method, however it is unclear if will also work NextSeq500 platform, employs 2-colour system. We created RRBS library and sequenced both HiSeq2500 NextSeq500, found no significant difference composition reads derived from either...
Abstract The rapidly growing collection of public single-cell sequencing data has become a valuable resource for molecular, cellular, and microbial discovery. Previous studies mostly overlooked detecting pathogens in human data. Moreover, existing bioinformatics tools lack the scalability to deal with big We introduce Vulture, scalable cloud-based pipeline that performs calling RNA (scRNA-seq) data, enabling meta-analysis host–microbial from domain. In our benchmarking experiments, Vulture...
Abstract The rapidly growing collection of public single-cell sequencing data have become a valuable resource for molecular, cellular and microbial discovery. Previous studies mostly overlooked detecting pathogens in human data. Moreover, existing bioinformatics tools lack the scalability to deal with big We introduce Vulture, scalable cloud-based pipeline that performs calling RNA (scRNA-seq) data, enabling meta-analysis host-microbial from domain. In our benchmarking experiments, Vulture...
In this study, the mitochondrial genome of Oxyeleotris lineolatus was first determined. The length entire mtDNA sequence 16,522 bp with (A + T) content 53.81%, and it contained 13 protein-coding genes, two rRNAs, 22 tRNAs, a control region. gene order orientation are similar to some typical fish species. data will provide useful molecular information for phylogenetic studies concerning O. its related
Abstract Summary With the recent advancement in single-cell RNA-sequencing technologies and increased availability of integrative tools, challenges arise easy fast access to large collections cell atlas. Existing atlas portals rarely are open sourced adaptable, do not support meta-analysis at level. Here, we present an source, highly optimised scalable architecture, named Scope+, allow quick access, cell-level selection data. We applied this architecture our well-curated 5 million COVID-19...
Abstract With the recent advancement in single-cell technologies and increased availability of integrative tools, challenges arise easy fast access to large collections cell atlas. Existing atlas portals rarely are open sourced adaptable, do not support meta-analysis at level. Here, we present an source, highly optimised scalable architecture, named Scope+, allow quick access, cell-level selection data. We applied this architecture our well-curated 5 million Covid-19 blood immune cells, as a...
Understanding the emergence of human notochordal cells (NC) is essential for development regenerative approaches. We present a comprehensive investigation into specification and generation bona fide NC using straightforward pluripotent stem cell (PSC)-based system benchmarked with fetal notochord. By integrating in vitro vivo transcriptomic data at single-cell resolution, we establish an extended molecular signature overcome limitations associated studying lineage early developmental stages....