A5019503556- Animal Nutrition and Physiology
- Cancer-related molecular mechanisms research
- Research in Cotton Cultivation
- Genetic and phenotypic traits in livestock
- Plant Stress Responses and Tolerance
- Environmental Toxicology and Ecotoxicology
- Growth Hormone and Insulin-like Growth Factors
- Soil Carbon and Nitrogen Dynamics
- Microbial Metabolic Engineering and Bioproduction
- Gut microbiota and health
- Biofuel production and bioconversion
- Dengue and Mosquito Control Research
- Ecology and Vegetation Dynamics Studies
- Genomics and Chromatin Dynamics
- Circular RNAs in diseases
- Tannin, Tannase and Anticancer Activities
- Heat shock proteins research
- Tea Polyphenols and Effects
- Mycorrhizal Fungi and Plant Interactions
- Livestock and Poultry Management
- Curcumin's Biomedical Applications
- Bee Products Chemical Analysis
- Bone fractures and treatments
- Genetic Associations and Epidemiology
- Cholesterol and Lipid Metabolism
Xinjiang Agricultural University
2020-2024
Central South University of Forestry and Technology
2012-2024
Central South University
2012-2024
Huazhong Agricultural University
2022-2024
Nanjing University
2022-2023
Cotton Research Institute
2023
Chinese Academy of Agricultural Sciences
2023
Henan Agricultural University
2018-2022
Tianjin University of Traditional Chinese Medicine
2021
Sichuan Agricultural University
2017-2020
Gallic acid (GA), a plant phenol found in fruits and vegetables, has been recently reported to attenuate ulcerative colitis (UC). However, the mechanism of GA UC remains unknown. In this study, we investigated therapeutic effects on from perspective gut microbiota supervised metabolic alterations vivo with 1H NMR-based metabolomics, which can provide holistic view understand functions UC. Rats dextra sulfate sodium (DSS)-induced were rectally administrated (6 mg kg-1) for 8 consecutive days....
Abstract The rice rhizosphere microbiota is crucial for crop yields and nutrient use efficiency. However, little known about how co‐occurrence patterns, keystone taxa functional gene assemblages relate to soil pH in the soils. Using shotgun metagenome analysis, microbiome was investigated across 28 fields east‐central China. At higher sites, taxonomic network of soils more complex compact, as defined by average degree, graph density complexity. Network stability greatest at medium (6.5 <...
The large economic losses caused by leg disorders have raised concerns in the broiler industry. Several types of broilers been identified, such as tibial dyschondroplasia (TD), femoral head necrosis (FHN), and valgus-varus deformity (VVD). In this study, phenotypic changes associated with VVD were examined using clinical diagnosis, anatomical examination, measured growth performance, bone traits, serum indicators. incidence among chicken population at a commercial facility Tangshan China was...
In addition to offering methionine, 2-hydroxy-4-methylthiobutyric acid (HMTBa) is also an organic and shows excellent bacteriostasis. Therefore, 3 experiments were conducted determine the influence of drinking water supplemented HMTBa in combination with acidifier on performance, intestinal development, microflora broilers. The different concentration (0.02-0.20%) blend other acids significantly reduced pH exerted antimicrobial activity dose-dependent manner vitro. outcomes from animal trial...
For lack of evidence to the contrary, it is now believed that FSH-suppressing actions follistatin are due its ability bind endogenous pituitary activin. Recent data have demonstrated a role for activin-B in mediating FSH hypersecretion after ovariectomy (OVX) and during secondary surge on estrus. Therefore, given produced within anterior tissue, considering potentially important function modulate activin bioactivity, we sought gain insights into regulation gene expression gland adult female...
Pigs are the most important source of meat and valuable biomedical models. However, porcine immune system, especially heterogeneity CD8 T cell subtypes, has not been fully characterized. Here, using single-cell RNA sequencing, we identified 14 major types from peripheral blood circulating cells pigs observed remarkable among types. Upon re-clustering CD8+ cells, defined four subtypes revealed their potential differentiation trajectories transcriptomic differences them. Additionally,...
Previous studies have revealed a significant association between SNPs found within the heparan sulfate 6-O-sulfotransferase 3 (HS6ST3) gene and obesity. This study identified novel 43-bp indel polymorphism in intron 1 of HS6ST3 1963 chickens from nine different breeds, three genotypes, designated II, ID DD, were observed. The frequency 'I' (0.62–0.87) allele was higher than that 'D' (0.13–0.38) allele. A total 777 individuals Gushi-Anka F2 resource population used for analysis associations...
Bone abnormality and leg disease in commercial broiler flocks are increasingly prominent, causing serious economic losses to the breeding industry. Valgus-varus deformity (VVD) is a common of long bone broilers that manifests as an outward or inward deviation tibiotarsus tarsometatarsus. There paucity studies on molecular mechanisms VVD.In this study, 6 cDNA libraries were constructed from spleen samples VVD birds normal birds. A total 1951 annotated lncRNAs, 7943 novel lncRNAs 30252 mRNAs...
Although large-scale and accurate identification of cis-regulatory elements on pig protein-coding long non-coding genes has been reported, similar study miRNAs is still lacking. Here, we systematically characterized the in muscle fat by adopting miRNAomes, ChIP-seq, ATAC-seq, RNA-seq Hi-C data. In total, 257 (85.95%) expressed including 226 known 31 novel were identified. Especially, associated with super-enhancers, active promoters, "A" compartment significantly higher than those typical...
Gossypium barbadense possesses a superior fiber quality because of its length and strength. An in-depth analysis the underlying genetic mechanism could aid in filling gap research regarding strength provide helpful information for breeding. Three quantitative trait loci related to were identified from recombinant inbred line (PimaS-7 × 5917) further analysis. RNA sequencing was performed tissues PimaS-7 5917 0-35 days postanthesis. Four specific modules closely secondary wall-thickening...
Drought stress significantly affects the growth, development, and yield of cotton, triggering response multiple genes. Among them, ascorbate peroxidase (APX) is one important antioxidant enzymes in metabolism reactive oxygen species plants, APX enhances ability plants to resist oxidation, thus increasing plant tolerance. Therefore, enhancing activity cells crucial improving resistance. Previous studies have isolated differentially expressed proteins under drought (
Lipid metabolism disorder caused by the upregulation of lipogenic genes is a typical feature prostate cancer. The synthesis fatty acids enhanced to accelerate development cancer and considered as potential therapeutic target. Epicatechin gallate, an active compound green tea, has been reported modulate lipid metabolism. In this research, role epicatechin gallate in cells was evaluated. results indicated that downregulates expression acetyl-CoA carboxylase, ATP citrate lyase, acid synthase...
The introduction of activated N-ras cDNA Into normal diploid human skin fibroblast cell cultures using the retroviral vector pZIPneo results in a spectrum morphologies ranging from near to, rare instances, dense piled-up colonies morphologically transformed cells. However, none clones isolated were as assessed by growth on agar or tumorigenicity nude mice. Introduction both c-myc and oncogene cDNAs into fibroblasts failed to produce transformation mice, although infection alone conferred...
Abstract Carboxyl ester lipase (CEL) encodes a cholesterol hydrolase that is secreted into the duodenum as component of pancreatic juice. The objective this study was to characterize CEL gene, investigate association between promoter variants and chicken phenotypic traits, explore gene regulatory mechanism. An insertion/deletion (indel) caused by 99-bp insertion fragment shown for first time in promoter, large differences allelic frequency were found among commercial breeds, indigenous feral...