Qin Chen

ORCID: 0000-0003-1821-2776
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About
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Research Areas
  • Plant Disease Resistance and Genetics
  • Chromosomal and Genetic Variations
  • Research in Cotton Cultivation
  • Plant Virus Research Studies
  • Photosynthetic Processes and Mechanisms
  • Wheat and Barley Genetics and Pathology
  • Plant-Microbe Interactions and Immunity
  • Plant Molecular Biology Research
  • Plant Gene Expression Analysis
  • Plant Stress Responses and Tolerance
  • Plant Pathogens and Resistance
  • Flame retardant materials and properties
  • Genomics and Phylogenetic Studies
  • Cancer-related molecular mechanisms research
  • Molecular Biology Techniques and Applications
  • Plant and Fungal Interactions Research
  • Fire dynamics and safety research
  • Gene expression and cancer classification
  • Epigenetics and DNA Methylation
  • Plant tissue culture and regeneration
  • Hemiptera Insect Studies
  • Plant nutrient uptake and metabolism
  • Plant biochemistry and biosynthesis
  • Legume Nitrogen Fixing Symbiosis
  • Rice Cultivation and Yield Improvement

Northwest A&F University
2017-2025

Chinese Academy of Sciences
2018-2025

Chengdu Institute of Biology
2021-2025

Xinjiang Agricultural University
2019-2025

Zhejiang A & F University
2025

Shanghai University
2025

The University of Texas MD Anderson Cancer Center
2023-2024

Anhui Agricultural University
2024

Second Affiliated Hospital of Zhejiang University
2024

Heilongjiang University of Chinese Medicine
2024

Current biofuel production relies on limited arable lands the earth, and is impossible to meet demands.  Oil producing algae are alternative feedstock with potential world's ambitious goal replace fossil fuels.  This review provides an overview of biological engineering aspects in processing technologies recent advances research development fuels approach.  The article covers biology, selection genetic modification species strains, systems design, culture media light management, harvest...

10.25165/ijabe.v2i4.200 article EN 2010-01-13

Genomic in situ hybridization (GISH) using genomic DNA probes from Thinopyrum elongatum (Host) D.R. Dewey (genome E, 2n = 14), bessarabicum (Savul. & Rayss) Á. Löve J, and Pseudoroegneria strigosa (M. Bieb.) S, was used to examine the constitution of intermedium Barkworth (2n 6x 42) ponticum (Podp.) 10x 70). Evidence GISH indicated that hexaploid Th. contained J s , S genomes, which genome related E bessarabicum. The homologous Ps. strigosa, while referred modified J- or E-type...

10.1139/g98-055 article EN Genome 1998-08-01

Periodontitis is an immune inflammatory disease that leads to progressive destruction of bone and connective tissue, accompanied by the dysfunction even loss periodontal ligament stem cells (PDLSCs). Pyroptosis mediated gasdermin-D (GSDMD) participates in pathogenesis diseases. However, whether pyroptosis mediates PDLSC loss, inflammation triggered involved pathological progression periodontitis remain unclear. Here, we found PDLSCs suffered GSDMD-dependent release interleukin-1β (IL-1β)...

10.3389/fcell.2021.663037 article EN cc-by Frontiers in Cell and Developmental Biology 2021-04-01

Phenylalanine ammonia-lyase is one of the most widely studied enzymes in plant kingdom. It a crucial pathway from primary metabolism to significant secondary phenylpropanoid plants, and plays an essential role growth, development, stress defense. Although PAL has been many actual only report reported on potato, five staple foods world. In this study, 14 StPAL genes were identified potato for first time using genome-wide bioinformatics analysis, expression patterns these further investigated...

10.3390/ijms23126833 article EN International Journal of Molecular Sciences 2022-06-20

Maintenance of genomic methylation patterns at DNA replication forks by DNMT1 is the key to faithful mitotic inheritance. often overexpressed in cancer cells and hypomethylating agents azacytidine decitabine are currently used treatment hematologic malignancies. However, toxicity these cytidine analogs their ineffectiveness treating solid tumors have limited wider clinical use. GSK-3484862 a newly-developed, dicyanopyridine containing, non-nucleoside DNMT1-selective inhibitor with low...

10.1093/narcan/zcad022 article EN cc-by-nc NAR Cancer 2023-03-11

The environmentally friendly, non-toxic, non-isocyanate polyurethane (NIPU) adhesives derived from CO 2 and green resources were synthesized.

10.1039/d4gc05323k article EN Green Chemistry 2025-01-01

Phenylalanine (Phe), an aromatic amino acid, is a key precursor of flavonoids, which are crucial for plant growth and development. Arogenate dehydratase (ADT) catalyzes the final step in Phe biosynthesis. This study identified eleven ADT genes G. hirsutum, twelve barbadense, six arboreum, raimondii. Among them, GhADT5 exhibited highest upregulation under alkali stress. Silencing using virus-induced gene silencing (VIGS) reduced cotton tolerance to also led decreased phenylalanine content,...

10.1186/s12870-025-06204-7 article EN cc-by-nc-nd BMC Plant Biology 2025-02-19

The ciliary body in the eye secretes aqueous humor and glycoproteins of vitreous maintains intraocular pressure. muscle controls shape lens through zonules to focus image onto retina. During embryonic development, epithelium is derived from optic vesicle, but molecular signals that control morphogenesis are unknown. We report lens-specific expression a transgenic protein, Noggin, can block BMP signaling mouse result failure formation processes. Co-expression BMP7 restores normal development...

10.1242/dev.129.19.4435 article EN Development 2002-10-01

Arabinogalactan proteins (AGPs) are a family of extracellular glycoproteins implicated in plant growth and development. With rapid the number genomes sequenced many species, members AGPs can now be predicted to facilitate functional investigation. Building upon previous advances identifying Arabidopsis AGPs, an integrated strategy systematical AGP screening for "classical" "chimeric" is proposed this study. A Python script named Finding-AGP compiled find AGP-like sequences filter candidates...

10.3389/fpls.2017.00066 article EN cc-by Frontiers in Plant Science 2017-01-25

Hypertension, sleep disorders, and depression are highly prevalent in the elderly population all associated with cognitive impairment, but role that quality play association between hypertension impairment is unclear. The aim of this study was to investigate whether have a mediating impairment.A cross-sectional conducted collect data from Tongji Hospital Comprehensive Geriatric Assessment Database. Sleep quality, function were measured by Pittsburgh Quality Index (PSQI), Depression Scale...

10.3389/fnagi.2023.1051298 article EN cc-by Frontiers in Aging Neuroscience 2023-02-07

4-coumarate: CoA ligase (4CL) is not only involved in the biosynthetic processes of flavonoids and lignin plants but also closely related to plant tolerance abiotic stress. UV irradiation can activate expression 4CL genes plants, changed significantly response different phytohormone treatments. Although gene has been cloned potatoes, there have fewer studies family on potato genome-wide scale. In this study, a total 10 were identified whole genome. Through multiple sequence alignment,...

10.3390/ijms24021642 article EN International Journal of Molecular Sciences 2023-01-13

Grb2 (Growth factor receptor-bound protein 2) is a key adaptor in maintaining the ERK activity via linking Sos1 (Son of sevenless homolog 1) or other proteins to activated RTKs, such as EGFR. Currently, little knowledge available concerning post-translational modification (PTM) except for its phosphorylation. Since emerging evidences have highlighted importance SUMOylation (Small ubiquitin-related modifier), reversible PTM, modulating functions, we wondered if could be SUMOylated and thereby...

10.1186/1476-4598-13-95 article EN cc-by Molecular Cancer 2014-04-29

Late blight, caused by the pathogen Phytophthora infestans, is one of most devastating diseases potato. Here, we describe a new single dominant resistance gene, Rpi2, from Mexican diploid wild species Solanum pinnatisectum that confers high level and broad spectrum to late blight. The Rpi2 locus full complex isolates P. for which race specificity has not yet been demonstrated. This flanked RFLP-derived marker SpT1756 AFLP-derived SpAFLP2 with minimal genetic distance 0.8 cM, was mapped...

10.3389/fpls.2017.01729 article EN cc-by Frontiers in Plant Science 2017-10-04

Endothelial cells (ECs) are mechanosensitive undergoing morphological and functional changes in space. Ground-based study has provided a body of evidences about how ECs can respond to the effect simulated microgravity, however, these results need be confirmed by spaceflight experiments real microgravity. In this work, we cultured EA.hy926 on board SJ-10 Recoverable Scientific Satellite for 3 10 days, analyzed effects space microgravity ECs. Space suppressed glucose metabolism, modulated...

10.3389/fphys.2018.01025 article EN cc-by Frontiers in Physiology 2018-07-31

Abstract Ciclopirox (CPX) modulates multiple cellular pathways involved in the growth of a variety tumor cell types. However, effects CPX on colorectal cancer (CRC) and underlying mechanisms for its antitumor activity remain unclear. Herein, we report that exhibited strong antitumorigenic properties CRC by inducing cycle arrest, repressing migration, invasion affecting N-cadherin, Snail, E-cadherin, MMP-2, MMP-9 expression, disruption bioenergetics contributed to CPX-associated inhibition...

10.1038/s41419-020-02779-1 article EN cc-by Cell Death and Disease 2020-07-27
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