A5100401900- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Treatment of Major Depression
- Resilience and Mental Health
- Posttraumatic Stress Disorder Research
- Attention Deficit Hyperactivity Disorder
- Functional Brain Connectivity Studies
- Stress Responses and Cortisol
- Transcranial Magnetic Stimulation Studies
- Genetic Neurodegenerative Diseases
- Migration, Health and Trauma
- Neuroscience and Neural Engineering
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Advanced MRI Techniques and Applications
- Mental Health Research Topics
- Neuroinflammation and Neurodegeneration Mechanisms
- Maternal Mental Health During Pregnancy and Postpartum
- Sirtuins and Resveratrol in Medicine
- Metabolomics and Mass Spectrometry Studies
- Advanced Neuroimaging Techniques and Applications
- Disaster Response and Management
- Diet and metabolism studies
- Child Abuse and Trauma
Dalian Medical University
2018-2025
Chongqing Medical University
2016-2025
Second Affiliated Hospital of Chongqing Medical University
2018-2025
Capital Medical University
2014-2025
Northwest A&F University
2025
Institute of Soil and Water Conservation
2025
Heze University
2025
The University of Melbourne
2025
Tsinghua University
2025
Nanjing University of Information Science and Technology
2024
Major depressive disorder (MDD) is a debilitating mental disease with pronounced impact on the quality of life many people; however, it still difficult to diagnose MDD accurately. In this study, nontargeted metabolomics approach based ultra-high-performance liquid chromatography equipped quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was used find differential metabolites in plasma samples from patients and healthy controls. Furthermore, validation analysis focusing performed...
Major depressive disorder (MDD) in children and adolescents is a recurrent disabling condition globally but its pathophysiology remains poorly elucidated there are limited effective treatments available. We performed metabolic profiling of plasma samples based on ultra-high-performance liquid chromatography equipped with quadrupole time-offlight mass spectrometry to explore the potential biomarkers depression MDD. identified several perturbed pathways, including fatty acid...
This study investigated the psychological reactions of survivors 512 Wenchuan earthquake in China and risk factors associated with those reactions. The Impact Event Scale-Revised (IES-R), Type D Scale-14 (DS14), a self-developed trauma experience questionniare, demographic questionnaire were administered to 956 (389 males 567 females) Mianzhu, one cities most affected by earthquake. results showed that postraumatic stress disorder (PTSD) symptoms 84.8% two months after Significant PTSD...
Background: An increasing number of studies are reporting that ketamine could be treated as a novel antidepressant for major depressive disorder (MDD). Therefore, we performed this meta-analysis to comprehensively and systematically assess the efficacy treating patients with MDD. Method: Randomized, double-blind, placebo-controlled on versus placebo MDD were searched up April 2016 in medical databases (PubMed, CCTR, Web Science, Embase, CBM-disc, CNKI). Three treatment time points (24 72 h,...
Abstract Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in single stress-induced depression model, which limited the identification MDD. depressive-like behaviors were induced by four well-validated stress models rats, including chronic unpredictable mild stress, learned helplessness restraint social...
To investigate the prevalence of and personal professional characteristics associated with burnout, psychological morbidity, job stress, satisfaction in Chinese neurologists.The China Neurologist Association conducted a national cross-sectional study from September 2014 to March 2015. A questionnaire including Maslach Burnout Inventory, 12-item General Health Questionnaire, Consultants' Mental questions assessing characteristics, career satisfaction, current doctor-patient relationships was...
Anxiety disorders are common in children and adolescents, uncertainty remains regarding the optimal strategy of psychotherapies this population.To compare rank different types ways delivering psychological treatments for anxiety adolescents.PubMed, Cochrane Central Register Controlled Trials, EMBASE, PsycINFO, Web Science, CINAHL (Cumulative Index to Nursing Allied Health Literature), ProQuest Dissertations, LILACS (Literatura Latino Americana em Ciências da Saúde), international trial...
Major depressive disorder (MDD) is a heterogeneous and multi-factorial disorder, the underlying molecular mechanisms remain largely unknown. However, many studies have indicated that depression in response to different stress may differ. After screening, 28-30 rats were included each model of (chronic unpredictable mild (CUMS); learned helplessness (LH); chronic restraint (CRS); or social defeat (SD)). Non-targeted gas chromatography-mass spectrometry was used profile metabolic changes...
Abstract Background With the increasing aging population, dementia has become a significant socioeconomic burden. However, effects of albumin on delayed recall (DR) impairment remain unclear, and there are limited reports sex race differences in this relationship. This study aimed to investigate association between levels DR older adults. Methods A total 1507 normal cognitive function 553 from National Health Nutrition Examination Survey (NHANES) 2011–2014 were included cross‐sectional...
Posttraumatic stress disorder (PTSD) and posttraumatic growth (PTG) are two different outcomes that may occur after experiencing traumatic events. Resilience rumination important factors determine the development of these trauma. We investigated association between factors, PTSD PTG, among Chinese survivors in an earthquake. With a convenience sample 318 from earthquake, we measured trauma exposure, PTSD, resilience, (Impact Event Scale-Revised, Growth Inventory, 10 item Connor-Davidson...
Major depressive disorder is a serious mental with high morbidity and mortality. The role of social stress in the development depression remains unclear. Here, we used defeat paradigm to induce depression-like behavior rats, then evaluated rats measured metabolic changes prefrontal cortex using gas chromatography-mass spectrometry. Within first week after procedure, sucrose preference test (SPT), open field (OFT), elevated plus maze (EPM) forced swim (FST) were conducted examine...