The field of multimodal medical image fusion has made huge progress in the past decade. However, previous methods always suffer from color distortion, blurring, and noise. To address these problems, we propose a novel Laplacian redecomposition (LRD) framework tailored to this article. proposed LRD two technical innovations. First, present decision graph decomposition scheme with enhancement obtain complementary information, redundant low-frequency subband images. Second, considering...

// Huihong Jiang 1, * , Huaguang Li 2, Ajian 3 Erjiang Tang 2 Dan Xu Yin Chen Yong Zhang Min Zhiyong 4 Xiaxing Deng 1 Moubin Lin Department of General Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School Medicine, Shanghai, China Center for Translational Yangpu Tongji Zhuji People's Zhejiang Province, Zhejiang, These authors have contributed equally this work Correspondence to: Lin, email: lmbin@hotmail.com Deng, xiaxingdeng@126.com Keywords: colorectal cancer, HALP,...

Abstract Background Colorectal cancer (CRC) is one of the most malignant tumors with high incidence, yet its molecular mechanism not fully understood, hindering development targeted therapy. Metabolic abnormalities are a hallmark cancer. Targeting dysregulated metabolic features has become an important direction for modern anticancer In this study, we aimed to identify new enzyme that promotes proliferation CRC and examine related mechanisms. Methods We performed RNA sequencing tissue...

Multi-focus image fusion (MFIF) is a fundamental task in processing. It generates an all-in-focus through multiple partly focused source images. There are common schemes that based on region detection and activity-level measurement, rule. We found it difficult to directly map between images focus maps. In this paper, we investigate the use of U-shape networks for end-to-end modeling MFIF. The novelty our framework two-fold. First, uses U-shaped network as feature extractor captures...

Abstract Lung cancer stem cell ( LCSC ) is critical in initiation, progression, drug resistance and relapse. Disadvantages showed conventional lung therapy probably because of its existence. In this study, line A549 cells propagated as spheroid bodies (named sphere cells) growth factors‐defined serum‐free medium. displayed CSC properties, including chemo‐resistance, increased proportion G0/G1 cells, slower proliferation rate, ability differentiation enhanced tumour formation vivo . Oncolytic...

BACKGROUNDLymphovascular invasion (LVI) is suggested to be an early and important step in tumor progression toward metastasis, but its prognostic value genetic mechanisms colorectal cancer (CRC) have not been well investigated. AIMTo investigate the of LVI CRC identify associated genomic alterations. METHODSWe performed a retrospective analysis 1219 patients evaluated for overall survival by Kaplan-Meier method multivariate Cox regression analysis.We also array-based comparative...

A comprehensive numerical study is conducted to explore the dynamic behaviors of a flame stabilized by triangular bluff body in straight chamber. The formulation accommodates complete set conservation equations with turbulence closure achieved large eddy simulation (LES) technique. G-equation-based level-set flamelet approach employed model interactions between premixed combustion and turbulence. Both non-reacting reacting flows are treated, special attention given effect inlet boundary...

BACKGROUND:Chronic constipation (CC) is a major public health problem worldwide, especially in elderly women. This study aimed to investigate the prevalence and risk factors of CC among women aged 50 years older Shanghai, China. MATERIAL AND METHODS:A cross-sectional survey was conducted on 1950 older, randomly sampled Yangpu District Shanghai from April October 2015. Information demographic characteristics, lifestyle habits, medical history, defecation situation collected through in-person...

Abstract This study presents a novel model for accurately estimating the densities of 48 refrigerant systems, categorized into five groups: Hydrofluoroethers (HFEs), Hydrochlorofluorocarbons (HCFCs), Perfluoroalkylalkanes (PFAAs), Hydrofluorocarbons (HFCs), and Perfluoroalkanes (PFAs). Input variables, including pressure, temperature, molecular weight, structural groups, were systematically considered. The explores efficacy both multilayer perceptron artificial neural network (MLP-ANN)...

In recent years, deep learning has made significant advancements in skin cancer diagnosis. However, most methods prioritize high prediction accuracy without considering the limitations of computational resources, making them impractical for wearable devices. this case, knowledge distillation emerged as an effective method, capable significantly reducing a model's reliance on and storage resources. Nonetheless, previous research suffers from two limitations: 1) student model can only...

The objective of pan-sharpening is to effectively fuse high-resolution panchromatic (PAN) images with limited spectral information and low-resolution multispectral (LR-MS) images, thereby generating a fused image high spatial resolution rich information. However, current fusion techniques face significant challenges, including insufficient edge detail, distortion, increased noise, robustness. To address these we propose multi-frequency spectral–spatial interaction enhancement network...

To investigate the predictive value of PIK3CA and TP53 mutation status in colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy.In this study, a total 315 histologically proven CRC were enrolled from Yangpu Hospital affiliated to Shanghai Tongji University between 2007 2011. Of these patients, 241 stage II/III received adjuvant chemotherapy. Formalin-fixed paraffin-embedded lesion samples curatively resected collected. Next-generation sequencing was performed...

Abstract In order to improve the therapeutic effects of mesenchymal stem cell (MSC)-based therapies for a number intractable neurological disorders, more favorable strategy regulate outcome bone marrow MSCs (bMSCs) was examined in present study. view wide range neurotrophic and neuroprotective effects, Tetramethylpyrazine (TMP), biologically active alkaloid isolated from herbal medicine Ligusticum wallichii, used. It revealed that treatment with 30–50 mg/l TMP 4 days significantly increased...

Optical coherence tomography (OCT) is a new intravascular imaging technique with high resolution and could provide accurate morphological infor￾mation for plaques in coronary arteries. However, its segmentation still co... | Find, read cite all the research you need on Tech Science Press

// Huihong Jiang 1, * , Erjiang Tang 2, Dan Xu 2 Ying Chen Yong Zhang 3 Min Yihua Xiao Zhiyong 4 Xiaxing Deng 1 Huaguang Li Moubin Lin Department of General Surgery, Ruijin Hospital Affiliated to Shanghai Jiaotong University School Medicine, Shanghai, China Center for Translational Yangpu Hospital, Tongji Zhuji People's Zhejiang Province, Zhejiang, These authors have contributed equally this work Correspondence to: Lin, email: lmbin@hotmail.com Li, yzxhgli@126.com Keywords: colorectal...

BACKGROUND:Intestinal complications are a major cause of morbidity after colorectal cancer surgery. This study aimed to develop an effective nomogram for predicting risk intestinal following MATERIAL AND METHODS:We retrospectively analyzed 1876 patients who underwent surgery at Yangpu and Zhuji hospitals from January 2013 October 2018. Intestinal were defined as obstruction, leakage or bleeding, peritonitis within 30 days A logistic regression model was used identify the factors associated...

p62/SQSTM1 (sequestosome-1) is a key protein involved in multiple cellular bioprocesses including autophagy, nutrient sensing, cell growth, death, and survival. Therefore, it implicated human diseases such as obesity cancer. Here, we show that the CUL5–ASB6 complex ubiquitin E3 ligase mediating p62 ubiquitination degradation. Depletion of CUL5 or ASB6 induced accumulation, overexpression promoted degradation p62. Functionally, can inhibit proliferation MEF hepatocellular carcinoma cells by...

Defocus blur estimation requires high-precision detection between the homogeneous region and transition edge. This paper develops a novel progressive design that effectively addresses this challenge. Our multi-interactive scheme could gradually learn characteristics of degraded input divide complex defocus into more manageable subnetworks. Specifically, we equally degrade source inputs combine them with complementary information In first two stages, feature interactive modules are introduced...

// Moubin Lin 1,3,* , Yajie Zhang 2,* Ajian Li 2 Erjiang Tang 1 Jian Peng 3 Wenxian Yong Liang Lu Yihua Xiao Qing Wei 4 Yin and Huaguang Center for Translational Medicine, Yangpu Hospital, Tongji University School of Shanghai, China Department General Surgery, RuiJin Hospital Affiliated to Shanghai Jiaotong Pathology, The Tenth People's * These authors have contributed equally this work Correspondence to: Lin, email: Li, Keywords : colorectal cancer, RNAi screening, chemotherapy, recurrence,...