- Neurobiology of Language and Bilingualism
- Neural and Behavioral Psychology Studies
- Reading and Literacy Development
- Neonatal and fetal brain pathology
- Multisensory perception and integration
- Functional Brain Connectivity Studies
- Infant Development and Preterm Care
- Wireless Body Area Networks
- Retinopathy of Prematurity Studies
- Advanced Neuroimaging Techniques and Applications
- Visual perception and processing mechanisms
- Language Development and Disorders
- Memory and Neural Mechanisms
- Stroke Rehabilitation and Recovery
- Children's Physical and Motor Development
- Acute Ischemic Stroke Management
- Neuroscience and Music Perception
- Neurological Disorders and Treatments
- Electromagnetic Fields and Biological Effects
- Ultrasound and Hyperthermia Applications
- Cerebral Venous Sinus Thrombosis
- Health, Environment, Cognitive Aging
- Human-Animal Interaction Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Behavioral Health and Interventions
University of Turku
2008-2024
Turku University Hospital
2020-2022
Federal Medical-Biological Agency
2018-2019
Institute of the Human Brain
2003-2006
University of Helsinki
2003-2004
We measured brain activation with functional magnetic resonance imaging (fMRI) while Finnish–Norwegian bilinguals silently translated sentences from Finnish into Norwegian and decided whether a later presented probe sentence was correct translation of the original sentence. The control task included silent reading decision within single language, Finnish. minus contrast activated left inferior frontal gyrus (Brodmann's area 47) basal ganglia. appears to be related active semantic retrieval...
Background: Cognitive decline and fatigue are typical in multiple sclerosis (MS). However, there is no official medication for either of these symptoms. Objective: The purpose this study was to estimate the effects a single dose rivastigmine on processing speed associated brain activity patients with MS subjective cognitive fatigue. Methods: Fifteen 13 healthy controls (HCs) matched age, gender education performed neuropsychological assessment functional (f)MRI. A modified version Paced...
We investigated the effects of mobile phone radiation on cerebral glucose metabolism using high-resolution positron emission tomography (PET) with 18 F-deoxyglucose (FDG) tracer. A long half-life (109 minutes) F isotope allowed a long, natural exposure condition outside PET scanner. Thirteen young right-handed male subjects were exposed to pulse-modulated 902.4 MHz Global System for Mobile Communications signal 33 minutes, while performing simple visual vigilance task. Temperature was also...
Increased propensity for risky behavior in adolescents, particularly peer groups, is thought to reflect maturational imbalance between reward processing and cognitive control systems that affect decision-making. We used functional magnetic resonance imaging (fMRI) investigate brain correlates of risk-taking effects influence 18-19-year-old male adolescents. The subjects were divided into low high groups using either personality tests or rates a simulated driving task. fMRI data analyzed...
Adolescents are characterized by impulsive risky behavior, particularly in the presence of peers. We discriminated high and low risk-taking male adolescents aged 18-19 years assessing their propensity for behavior vulnerability to peer influence with personality tests, compared structural differences gray white matter brain voxel-based morphometry (VBM) diffusion tensor imaging (DTI), respectively. also structures according participants' actual a simulated driving task two different social...
To study rehabilitation outcome in a chronic visual field defect patient using positron emission tomography (PET) imaging, clinical, and neurophysiological measures.A with was rehabilitated computer program over three-month period. Evaluations of effects were done before after training, follow-up perimetry, evoked potentials (VEP), subjective questionnaire, PET activation studies regional cerebral blood flow (rCBF).In the increased during also experienced improvement. In VEP, previously...
Abstract The present study investigated the effects of 902.4 MHz Global System for Mobile Communications (GSM) mobile phone radiation on cerebral blood flow using positron emission tomography (PET) with 15 O‐water tracer. Fifteen young, healthy, right‐handed male subjects were exposed to from three different locations (left ear, right forehead) and sham exposure test possible brain regions close source. Whole‐brain [ O]H 2 O–PET images acquired 12 times, 3 each condition, in a...
The multidisciplinary assessment of health problems after stroke should take into account not only motor, speech disorders, disability, but also postural balance, type and level mental degree working hand dysfunctions, cortical motor neuron functional indicators, risk factors for recurrent stroke.To develop a methodology the integrated effectiveness stage rehabilitation in patients ischemic (IS) stroke.Examinations were made 101 (mean age 59.78±8.63 years) IS middle cerebral arterial bed...
Using positron emission tomography (PET), we explored the neural correlates of an executive function, dual tasking, in patients with amnestic mild cognitive impairment (aMCI) and elderly controls. The experiment employed simple auditory visual tasks that were presented both isolation simultaneously to create a task condition requiring enhanced attentional control. Behaviorally, groups performed well, albeit made more errors on task. PET analysis focused at prefrontal regions where group...
Abstract Background Changes in brain structural connections appear to be important the pathophysiology of substance use disorders, but their role behavioral addictions, such as gambling disorder (GD), is unclear. GD also offers a model study addiction mechanisms without pharmacological confounding factors. Here, we used multimodal MRI data examine integrity white matter individuals with GD. We hypothesized that affected areas would fronto-striatal-thalamic circuit. Methods Twenty (mean age:...
Abstract Objectives: Impairments in visual perception are among the most common developmental difficulties related to being born prematurely, and they often accompanied by problems other domains. Neural activation participants prematurely full-term during tasks that assess several areas of has not been studied. To better understand neural substrates perceptual impairments, we compared behavioral performance brain activations adolescents very preterm (birth weight ≤1500 g or gestational age...
BackgroundFine motor and coordination problems are frequently reported among adolescents born preterm. We aimed to assess performance in hand tasks compare concurrent brain activation between very preterm at term 13 years.MethodsA total of 34 right-handed (gestational age less than 32 weeks/birth weight ≤1500 grams) 37 controls during 2003 2006 Turku University Hospital, Finland, were recruited. At years, finger opposition diadochokinesis assessed, functional magnetic resonance imaging data...
Adolescents born very preterm have an increased risk for anxiety, social difficulties and inattentiveness, i.e. the 'preterm behavioural phenotype'. The extreme end of these traits comprises core diagnostic features attention hyperactivity disorders autism spectrum disorder, which been reported to show aberrant dynamic resting-state functional network connectivity. This study aimed compare this dynamism between adolescents controls. A magnetic resonance imaging was performed on 24...