A5101970066- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Schizophrenia research and treatment
- Neonatal Respiratory Health Research
- Social and Educational Sciences
- Mental Health and Psychiatry
- Children's Physical and Motor Development
- Research in Social Sciences
- Psychosomatic Disorders and Their Treatments
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Cerebral Palsy and Movement Disorders
- Attention Deficit Hyperactivity Disorder
- Retinopathy of Prematurity Studies
- Pregnancy and preeclampsia studies
- Child Nutrition and Feeding Issues
- Infectious Encephalopathies and Encephalitis
- Psychiatric care and mental health services
- Behavioral and Psychological Studies
- Social and Cultural Dynamics
- Advanced MRI Techniques and Applications
- Preterm Birth and Chorioamnionitis
- Childhood Cancer Survivors' Quality of Life
- Ethics in Clinical Research
- Genetic Associations and Epidemiology
University of Turku
2010-2024
Turku University Hospital
2016-2024
Kainuun keskussairaala
2018
Lund University
1983-1991
ABSTRACT– Prediction of 5–8 year outcome from presenting symptoms and background data was attempted in a sample 110 firstadmitted schizophrenics. Correlations between criteria single predictors as well factor analytically derived clusters were studied. A rather consistent pattern symptom variables personality social found to be predictive outcome. ‘Atypical’ associated with good prognosis while longitudinal indicative ‘high‐risk personality', or duration severity illness, related bad...
Of 110 consecutive, young schizophrenic patients, 18 (16.4%) died during a follow-up period of 14-17 years from first admission. Fifteen them met with sudden death. Definite suicide was proven in 10 cases (9%). Suicide associated chronicity course, social dependency, and lowered efficiency. Some type warning present all cases. The frequency thoughts attempts high the whole material. were protracted non-regressive symptomatology, readmission to hospital, intervention, female sex. disparity...
Prediction of 14‐ to 17‐year outcome from symptoms present at admission and psychosocial personality data was attempted among the 92 survivors a group 110 first‐admitted schizophrenic patients. Three different criteria were used correlations between these varied low high. Using discriminant analytical approach where all 107 predictor variables predict combination criteria, 23% variance could be explained, which should compared with 49% in previous 5‐ 9‐year study on same material. At least...
Abstract Amphetamine added to maintenance therapy with neuroleptic drugs was accompanied by relief of complaints in 32 48 chronic schizophrenic patients a long‐standing incapacity for work. In 22 cases this followed increased work efficiency. These gains were lost at experimental withdrawal amphetamine. The response amphetamine varied type symptomatology. All current regressive symptoms meant worsening spite concomitant treatment, accordance the dopamine hypothesis. Non‐regressive subjects...
Aim To study the association between Hammersmith Infant Neurological Examination (HINE) at age 2 years and neurocognition 11 in children born very preterm. We hypothesized that HINE would be associated with neurocognition, is, neurological, motor, cognitive outcomes years. Method A total of 174 (mean gestational 29.0wks, SD 2.7; minimum 23.0, maximum 35.9; 95 [55%] males, 79 [45%] females) preterm (birthweight ≤1500g/gestational <32wks), were included a prospective cohort recruited from...
Two series of first adissions ‐ mental hospital patients from the years 1964–67 have been followed up after 5–8 year with regard to social prognosis, and (in male index cases) heredity. One group was, according case records stay, diagnosed as surfering classical, regressive schizophrenia ( n = 56), all seemingly atypical cases excluded. A second 54) had exhibited picture non‐regressive (pseudoneurotic) schizophrenia. detailed account syptomatology is presented, special emphasis laid on...
To evaluate the rate of developmental coordination disorder (DCD) and its correlation to cognition self-experienced health-related quality life (HRQoL) in children born very preterm.Prospective follow-up study.Regional population preterm Turku University Hospital, Finland, 2001-2006.A total 170 were followed up until 11 years age.Motor cognitive outcomes evaluated using Movement Assessment Battery for Children - Second Edition (Movement ABC-2) Wechsler Intelligence Scale Fourth Edition,...
A total of 154 patients admitted for the first time to hospital a psychotic or affective disorder in 1925 were rediagnosed accordance with DSM-III and Leonhard's diagnostic system. Symptoms rated rating protocol containing 33 items based on descriptions cycloid psychoses. The followed up through parish registers records. Of 42 cases considered be psychosis at index admission, 34 prognostically verified. symptom ratings analysed by K-means cluster analysis test whether psychoses would...
State of health, work and social relations functioning as outcome measures in 95 survivors out 110 schizophrenic probands proved to be only moderately intercorrelated at follow-up 6-9 years after first hospital admission. Total sick-leave time was the treatment measure mirroring combined outcome, while variables were connected working self-supporting ability. Among competence data, living partnership, producing children falling ill associated with a favourable outcome. Self-reports simple...
The aim of the study was to examine how goal-setting skills children with attention-deficit/hyperactivity disorder (ADHD) can be predicted elements working memory. involved 30 an ADHD diagnosis and healthy volunteers. IQ participants assessed, symptoms were evaluated by parents. Each memory assessed two measures as well skills. In tests central executive in one visuospatial sketch pad, performed more poorly than did controls but not phonological loop. Children on mastery scores Strategy...
Background: Children with encephalitis have increased risk for long-term neurological sequelae. We investigated minor dysfunction (MND) and cognitive performance as a measurement outcome of in childhood. Materials Methods: ( n = 98) treated Turku University Hospital during the years 1995–2016 were retrospectively identified. included patients without severe developmental delay before recorded disability caused by encephalitis. MND was assessed using Touwen examination. Age-appropriate...
We compared cognitive profile and neuropsychological performance in 9-year-old offspring of mothers who were treated with metformin or insulin for gestational diabetes mellitus (GDM).A total 172 children whose randomly assigned to receive either GDM studied at the age 9 years. Of these children, 127 from Turku, Finland (63 64 insulin), 45 Oulu, (19 26 insulin). Clinical demographic background characteristics obtained enrolment, birth, 9-year follow-up. Cognitive profiles examined years...
Children born very preterm (<32 gestational weeks and/or birth weight ≤1500 g) are at elevated risk for reading difficulties. This study aimed to investigate fluency and comprehension 11 analyze the associations between literacy skills 7 in 134 Finnish-speaking children. At 11, were evaluated. 7, pre-reading skills, decoding, writing assessed. Results showed that there more children with weak compared a normative test population. Reading was age appropriate. Additionally, 62% 68% of had...
The aims of this study were to 1) assess the predictive value psychological assessment at five years age on need for educational support in very preterm children, and 2) report neuropsychological profile children eleven risk factors poorer functions. A cohort 167 was included (birth weight ≤ 1500 g and/or gestational < 32 weeks). At age, intellectual functioning assessed with Wechsler Preschool Primary Scale Intelligence-Revised performance NEPSY II. functions using II data services...
A 14-17 year follow-up study of a first admission sample nonregressive schizophrenic cases revealed phenomenological and diagnostic consistency over time. Some improved adapted well in society but considerable proportion developed into chronic syndromes. Schizophrenic deterioration was also manifested among those who adhered to course without ever revealing frank psychotic decompensation. Treatment consumption disability were high. Prognosis outcome were, the main, similar parallel series...
The aim of this study is to investigate the working memory (WM) very-low-birthweight (VLBW, ≤ 1500 g) children at age 11 years using Baddeley's WM model. A regional cohort 95 VLBW was assessed for domains model (central executive [CE], visuospatial sketchpad [VS], and phonological loop [PL]) subtests from Working Memory Test Battery Children (WMTB-C) Wechsler Intelligence Scale – Fourth Edition (WISC-IV). were categorized into three groups according their degree brain pathology (normal,...
This Finnish regional birth-cohort study compared the school performance of very preterm and full-term children when they reached 11 years age.Teachers rated educational abilities 123 133 controls at age as well support services received. The were all born in Turku University Hospital between 2001 2005. In group, neurosensory impairments confirmed two corrected age, full-scale intelligence quotient (IQ) was assessed using Wechsler Intelligence Scale, Fourth Edition.Educational abilities,...
Working memory (WM) difficulties are often observed in children born preterm. We examined whether performance-based measures of WM components associated with parent- and teacher-rated the everyday life very preterm and/or at low birth weight (VPT/VLBW) 11 years (
ABSTRACT: Objective: Executive function (EF) problems of children born at very low birth weight (VLBW; ≤1500 g) or gestational age (VLGA; <32 weeks) may present differently school compared to the home environment. Ecological assessment EF including parent- and teacher-rated profiles associated risk factors 11-year-old VLBW VLGA was evaluated. Methods: A total 125 132 controls were assessed using Behavior Rating Inventory EF, which includes 8 subscales that form Behavioral Regulation...
Prematurity has been shown to affect social competence in children and adults. Our aim was evaluate profiles of self-reported behaviours loneliness preterm- term-born adolescents.Preterm (≤1500 g and, or, <32 gestational weeks)- infants were recruited Turku University Hospital from 2001 2006. The Multisource Assessment Children's Social Competence Scale the Peer Network Dyadic Loneliness completed at age 11. Profiles labelled as low, average or high.A total 172 preterm-born 134 adolescents...
Abstract Aim To investigate how the aetiology of very preterm birth/very low birth weight is associated with mortality and later neurodevelopmental outcomes. Methods Very preterm/very low‐birth singletons were categorised based on birth: spontaneous ( n = 47, 28.1%), premature rupture membranes 56, 33.5%) or placental vascular pathology 64, 38.3%). Mortality, cerebral palsy, severe cognitive impairment by 11 years age (<2SD) mean full‐scale intelligence quotient at studied in association...
Preterm birth affects the academic development of children, especially in mathematics. Remarkably, only a few studies have measured specific effects preterm on mathematical skills primary school. The aim this study was to compare 11-year-old with an IQ above 70, born very (N = 64) and full-term 72) variety 5th grade cognitive abilities important for learning. measures were spontaneous focusing numerosity (SFON), quantitative relations (SFOR), arithmetic fluency, mathematics achievement,...
ABSTRACT Regressive course during a 14–17 year follow‐up in 54 non‐regressive (pseudoneurotic, borderline, latent) schizophrenic subjects was predicted from about 100 variables studied on first admission. A significant prediction could not be achieved. This finding lends additional support to our previous interpretation that patients with syndrome are schizophrenics. large number of them will run typical course, but we unable predict initial data who do so. The few possibly predictive seemed...