A5101532003- Insect-Plant Interactions and Control
- Blood properties and coagulation
- Skin and Cellular Biology Research
- Bee Products Chemical Analysis
- Plant Virus Research Studies
- Healthcare and Venom Research
- Weed Control and Herbicide Applications
- Insect and Pesticide Research
- Advanced Drug Delivery Systems
- Hemiptera Insect Studies
- Insect Resistance and Genetics
- Drug Solubulity and Delivery Systems
- Pharmaceutical studies and practices
- Phytochemicals and Antioxidant Activities
- Tendon Structure and Treatment
- Orthoptera Research and Taxonomy
- Turfgrass Adaptation and Management
- Biological Control of Invasive Species
- Proteins in Food Systems
- Genetics and Plant Breeding
- Lipid metabolism and biosynthesis
- Cellular Mechanics and Interactions
- Hippo pathway signaling and YAP/TAZ
- Transgenic Plants and Applications
- Biological Activity of Diterpenoids and Biflavonoids
Kathmandu University
2021-2025
Wichita State University
2025
University of Southern California
2023
RIKEN
2017-2023
Infant
2022
RIKEN Center for Biosystems Dynamics Research
2015
Arkansas Agricultural Experiment Station
2006-2007
ABSTRACT The development of permanent superhydrophobic surfaces has attracted significant attention due to their usage in many applications, particularly environmental and biomedical remediations. Among the various fabrication techniques, electrospinning emerged as an advantageous flexible method for fabricating nanofibers with tailored surface characteristics. In this study, we explore enhancement properties by incorporating Teflon particles into matrices polystyrene (PS) polyvinyl chloride...
A functional response study of the eight most common arthropod predators cotton bollworm, Helicoverpa zea (Boddie), eggs was conducted in laboratory. Predators were starved for 24 h, and single exposed to different prey density treatments. Predation observed at 6, 12, h after feeding trials began. At highest (150 per predator), Hippodamia convergens Guerin-Meneville Collops quadrimaculatus (F.) adults Chrysopa oculata Say larvae showed consumption rates (116, 85, 119 eggs/24 respectively),...
The present study is focused on the availability of microbial sources capable producing xylanase, a hemicelluloses-degrading enzyme with multiple modes action along specificity, and their real-world applications. For accumulation suitable data, article surfing was carried out using search engines viz. Hinari PubMed; irrelevant duplicate articles were discarded summarized in narrative way herein. This review written aiming to bridge recent research activities commercial xylanase going around...
Abstract Nuclear accumulation of transglutaminase 2 (TG2) is an important step in TG2-dependent cell death. However, the underlying molecular mechanisms for nuclear translocation TG2 are still poorly understood. In this study, we demonstrated that acyclic retinoid (ACR) induced JHH-7 cells, a hepatocellular carcinoma (HCC) leading to their apoptosis. We further mechanism nuclear-cytoplasmic trafficking and effect ACR on it. identified novel 14-amino acid localization signal (NLS) 466...
Abstract Hepatocellular carcinoma (HCC) is the 3 rd most deadly malignancy. Activated hepatic stellate cells (aHSC) give rise to cancer-associated fibroblasts in HCC and are considered a potential therapeutic target. Here we report that selective ablation of stearoyl CoA desaturase-2 ( Scd2 ) aHSC globally suppresses nuclear CTNNB1 YAP1 tumors tumor microenvironment prevents liver tumorigenesis male mice. Tumor suppression associated with reduced leukotriene B4 receptor 2 (LTB4R2) its high...
A 2-yr field study was conducted to examine the effectiveness of two sampling methods (visual and plant washing techniques) for western flower thrips, Frankliniella occidentalis (Pergande), five (visual, beat bucket, drop cloth, sweep net, vacuum) cotton fleahopper, Pseudatomoscelis seriatus (Reuter), in Texas cotton, Gossypium hirsutum (L.), develop sequential plans each pest. The technique gave similar results visual method detecting adult but detected significantly higher number thrips...
Abstract Thrips (Thysanoptera: Thripidae( and cotton fleahoppers, Pseudatomoscelis seriatus (Reuter( (Hemiptera: Miridae(, are considered to be significant economic pests of in Texas, USA. A 2-year field study evaluated the influence planting date, tillage practice, Bt on seasonal abundance patterns thrips fleahoppers their within-plant distribution cotton. were sampled visually while both with a 'beat bucket' at weekly intervals throughout growing season. infestations had two distinct...
Abstract Transglutaminase 2 (TG2) is a multifunctional protein that promotes or suppresses tumorigenesis, depending on intracellular location and conformational structure. Acyclic retinoid (ACR) an orally administered vitamin A derivative prevents hepatocellular carcinoma (HCC) recurrence by targeting liver cancer stem cells (CSCs). In this study, we examined the subcellular location-dependent effects of ACR TG2 activity at structural level characterized functional role its downstream...
A 2-year field study was conducted in the southern High Plains region of Texas to evaluate effect tillage system and cotton planting date window on seasonal abundance activity patterns predacious ground beetles. The experiment deployed a split-plot randomized block design with as main-plot factor subplot factor. There were two levels for each systems conservation (30% or more soil surface is covered crop residue) conventional tillage. treatments early May (normal planting) June (late...
We previously reported the importance of induced nuclear transglutaminase (TG) 2 activity, which results in hepatic cell death, ethanol-induced liver injury. Here, we show that co-incubation either human cells or mouse primary hepatocytes derived from wild-type but not TG2
This study explores the formulation and assessment of herbal antioxidant tablets derived from Urtica dioica (stinging nettle) extracts for arthritis osteoarthritis treatment. Various extraction methods were compared, revealing that 100% dehydrated ethanol at 45 degrees Celsius four hours in a Soxhlet apparatus resulted an 89% phenolic extraction. Although ethyl acetate yielded highest extract (187%), its toxicity led to selection further The Folin-Ciocalteu method determined total content....
Three planting-date windows [early — 3 weeks before (i.e., 26–29 April) the recommended optimum planting window; timely commonly window of 16–19 May; and late after 6–9 June) window] three patterns (Solid solidrow stand; Skip 2×1 two rows planted, one row skipped; 2×2 skipped) were evaluated to determine their influence on abundance population dynamics arthropods during years in cotton, Gossypium hirsutum L., Texas Rolling Plains. Arthropod species sampled included thrips, Frankliniella...
Abstract A microsatellite‐enriched partial genomic DNA library of Lygus hesperus was generated and screened by sequencing. Ten polymorphic microsatellite marker loci were characterized genotyping 92 insect samples. The observed number alleles ranged from three to seven with an average 4.5 (SE ± 0.45), while the effective 1.21 3.02 2.14 0.20). Significant deviations Hardy–Weinberg expectations detected at loci. linkage disequilibrium also between LhMS2‐54 LhMS3‐32. Seven L. markers could be...
Abstract Population abundance and species composition of rice green leafhoppers was monitored by sweepnetsampling or lighttrapping from more than 116 growing locations in different altitudinal regions Nepal 1992 to 1994. Three leafhopper Nephotettix virescens, N. nigropictus Recilia dorsalis, were found most samples, a few similar malayanus occasionally observed. virescens predominant (80%) samples low altitude fields ( <500 m), its population high >1000 m) negligible absent. nigropictus,...
Objective: This study aims to prepare the taste-masked granules of Mirtazapine by mass extrusion technique and formulate it into an oral dispersible tablet using different super disintegrates. Methods: Taste masked mirtazapine were prepared Eudragit EPO in ratios. The drug-polymer ratio was optimized based on percent drug release SSF SGF. masking efficacy complex determined developing bitterness threshold value Mirtazapine. selected formulated oro-dispersible direct compression method. A...
Honey is a natural sweet substance produced by Apis sp. from floral nectar or other plant parts which are gathered, modified and stored in the honeycombs honeybees. The current research was aimed to analyze quality parameters of locally available honey. samples laboriosa mellifera were collected during spring 2019 & 2021 autumn Bagmati province, Nepal. Samples analyzed their physicochemical phytochemical properties. result shows that, pH ranged between [4.467 0.0306 - 5.05 0.02],...
Propolis is a waxy material obtained from honey bee hives. The physical and chemical property of this product variable based on the source hive, plant biodiversity where honeybee feed, season collection, geographical origin etc. has several useful compounds, among them polyphenols are mainly contributing for their broad spectrum medicinal quality such as antimicrobial, antifungal, antibacterial, anti-inflammatory activities well antioxidant properties. present study aims to analyze ethanolic...
Topical therapy with emulgel -type of products allows efficient delivery bioactive compounds additional benefits to patients. This research aimed design, optimize, formulate, and evaluate in vitro parameters between gels loaded a microemulsion extracted capsaicin their standard. A crude form was from capsicum. Using Box Behnken 15 different microemulsions were made by ultrasonication optimized varying three independent variables (amount olive oil, Hydrophilic-lipophilic balance value...
Objectives: We aimed to formulate and optimize bilayer tablets of metoprolol tartrate consisting both immediate sustained release layer. Methods: A 23 factorial design was employed in formulating the GFDDS which parameters, such as amount HPMC (X1), sodium bicarbonate + citric acid (X2), crospovidone (X3) were characterized independent variables, whereas percent at 30 min (Y1), 4 hr (Y2), 8 (Y3), floating lag time (Y4), total (Y5) considered dependent variables. Findings: The formulations...